Computational quality-by-design strategy to validate high-performance liquid chromatography method for the estimation of meloxicam in bulk dosage forms and milk samples
In conclusion, the optimized and validated RP-HPLC method of meloxicam may further be used for the analysis of drug content in pharmaceutical dosage forms in addition to biological fluids.PMID:37882956 | DOI:10.1007/s44211-023-00448-9 (Source: Anal Sci)
Source: Anal Sci - October 26, 2023 Category: Chemistry Authors: Vaskuri G S Sainaga Jyothi Harithasree Veerabomma Chantibabu Katta Jitender Madan Source Type: research
Computational quality-by-design strategy to validate high-performance liquid chromatography method for the estimation of meloxicam in bulk dosage forms and milk samples
In conclusion, the optimized and validated RP-HPLC method of meloxicam may further be used for the analysis of drug content in pharmaceutical dosage forms in addition to biological fluids.PMID:37882956 | DOI:10.1007/s44211-023-00448-9 (Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry)
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - October 26, 2023 Category: Chemistry Authors: Vaskuri G S Sainaga Jyothi Harithasree Veerabomma Chantibabu Katta Jitender Madan Source Type: research
Computational quality-by-design strategy to validate high-performance liquid chromatography method for the estimation of meloxicam in bulk dosage forms and milk samples
In conclusion, the optimized and validated RP-HPLC method of meloxicam may further be used for the analysis of drug content in pharmaceutical dosage forms in addition to biological fluids.PMID:37882956 | DOI:10.1007/s44211-023-00448-9 (Source: Anal Sci)
Source: Anal Sci - October 26, 2023 Category: Chemistry Authors: Vaskuri G S Sainaga Jyothi Harithasree Veerabomma Chantibabu Katta Jitender Madan Source Type: research
Computational quality-by-design strategy to validate high-performance liquid chromatography method for the estimation of meloxicam in bulk dosage forms and milk samples
In conclusion, the optimized and validated RP-HPLC method of meloxicam may further be used for the analysis of drug content in pharmaceutical dosage forms in addition to biological fluids.PMID:37882956 | DOI:10.1007/s44211-023-00448-9 (Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry)
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - October 26, 2023 Category: Chemistry Authors: Vaskuri G S Sainaga Jyothi Harithasree Veerabomma Chantibabu Katta Jitender Madan Source Type: research
Computational quality-by-design strategy to validate high-performance liquid chromatography method for the estimation of meloxicam in bulk dosage forms and milk samples
In conclusion, the optimized and validated RP-HPLC method of meloxicam may further be used for the analysis of drug content in pharmaceutical dosage forms in addition to biological fluids.PMID:37882956 | DOI:10.1007/s44211-023-00448-9 (Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry)
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - October 26, 2023 Category: Chemistry Authors: Vaskuri G S Sainaga Jyothi Harithasree Veerabomma Chantibabu Katta Jitender Madan Source Type: research
Computational quality-by-design strategy to validate high-performance liquid chromatography method for the estimation of meloxicam in bulk dosage forms and milk samples
In conclusion, the optimized and validated RP-HPLC method of meloxicam may further be used for the analysis of drug content in pharmaceutical dosage forms in addition to biological fluids.PMID:37882956 | DOI:10.1007/s44211-023-00448-9 (Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry)
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - October 26, 2023 Category: Chemistry Authors: Vaskuri G S Sainaga Jyothi Harithasree Veerabomma Chantibabu Katta Jitender Madan Source Type: research
Seasonal distribution of repeat breeder cows and evaluation of modified protocols for post AI treatment during summer
In this study, one farm in Northern Greece was chosen on the basis of subfertility. First, the available reproductive data of the previous year were evaluated; then, the farmer was advised to use the most common treatments for RB [GnRH with the third artificial insemination (AI+GnRH) or ovsynch in cows found empty after the second AI], and their efficacy was monitored throughout the year. Cows (n = 147) 2.5 to 4.5 years old were included. During the next year, post AI treatments (meta-ovsynch and meta-AI) were used during summer; GnRH (100 μg of gonadorelin) alone or in combination with meloxicam (0.5 mg/kg BW) was used d...
Source: Tropical Animal Health and Production - October 10, 2023 Category: Veterinary Research Source Type: research
Photocatalysis-PMS oxidation system based on CQDs-doped carbon nitride nanosheets for degradation of residual drugs in water
This study provides valid residual drugs degradation under the dual conditions of visible light catalytic oxidation and persulfate oxidation, which will be a novel perspective for advanced oxidation technology to effectively remove organic pollutants from water.PMID:37752394 | DOI:10.1007/s11356-023-30005-w (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - September 26, 2023 Category: Environmental Health Authors: Yongqiang Wang Yibo Bai Che Han Zaimei Li Xiaowen Lun Conglu Zhang Source Type: research
Preemptive QP001, a fast-acting meloxicam formulation, provides analgesia and reduces opioid consumption following abdominal surgery: a randomized controlled trial
ConclusionPreoperative/preemptive QP001 provides analgesia and reduces opioid consumption in patients with moderate to severe pain following abdominal surgery, while maintaining a favorable safety profile. (Source: Inflammopharmacology)
Source: Inflammopharmacology - August 30, 2023 Category: Drugs & Pharmacology Source Type: research
Vaccination against Extracellular Vimentin for Treatment of Urothelial Cancer of the Bladder in Client-Owned Dogs
Cancers (Basel). 2023 Aug 3;15(15):3958. doi: 10.3390/cancers15153958.ABSTRACTIt was recently shown that targeting extracellular vimentin (eVim) is safe and effective in preclinical models. Here, we report the safety and efficacy in client-owned dogs with spontaneous bladder cancer of CVx1, an iBoost technology-based vaccine targeting eVim in combination with COX-2 inhibition. This was a single-arm prospective phase 1/2 study with CVx1 in 20 client-owned dogs with spontaneous UC which involved four subcutaneous vaccinations with CVx1 at 2-week intervals for induction of antibody titers, followed by maintenance vaccinations...
Source: Cancer Control - August 12, 2023 Category: Cancer & Oncology Authors: Diederik J M Engbersen Judy R van Beijnum Arno Roos Marit van Beelen Jan David de Haan Guy C M Grinwis Jack A Schalken J Alfred Witjes Arjan W Griffioen Elisabeth J M Huijbers Source Type: research
An eco-friendly fluorometric assay for high-sensitive meloxicam quantitation in biological matrices
Analyst, 2023, Accepted Manuscript DOI: 10.1039/D3AN01211E, PaperZhong-Xia Wang, Kai-Qi Liu, Xiang-Ying Meng, Feng Li, Heng-Ye Li, Hang Gao, Wei Wang Meloxicam (Mel), as a powerful and effective anti-inflammatory drug, is commonly employed for the treatment of various inflammatory diseases, however, the use of Mel at high-doses or for extended periods... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Analyst latest articles)
Source: RSC - Analyst latest articles - August 3, 2023 Category: Chemistry Authors: Zhong-Xia Wang Source Type: research
Cancers, Vol. 15, Pages 3958: Vaccination against Extracellular Vimentin for Treatment of Urothelial Cancer of the Bladder in Client-Owned Dogs
beth J. M. Huijbers
It was recently shown that targeting extracellular vimentin (eVim) is safe and effective in preclinical models. Here, we report the safety and efficacy in client-owned dogs with spontaneous bladder cancer of CVx1, an iBoost technology-based vaccine targeting eVim in combination with COX-2 inhibition. This was a single-arm prospective phase 1/2 study with CVx1 in 20 client-owned dogs with spontaneous UC which involved four subcutaneous vaccinations with CVx1 at 2-week intervals for induction of antibody titers, followed by maintenance vaccinations at 2-month intervals. Additionally, daily cyclooxygen...
Source: Cancers - August 3, 2023 Category: Cancer & Oncology Authors: Diederik J. M. Engbersen Judy R. van Beijnum Arno Roos Marit van Beelen Jan David de Haan Guy C. M. Grinwis Jack A. Schalken J. Alfred Witjes Arjan W. Griffioen Elisabeth J. M. Huijbers Tags: Article Source Type: research
Development of Prediction Model Using Machine-Learning Algorithms for Nonsteroidal Anti-inflammatory Drug-Induced Gastric Ulcer in Osteoarthritis Patients: Retrospective Cohort Study of a Nationwide South Korean Cohort
CONCLUSIONS: We obtained a prediction model for NSAID-induced gastric ulcers using the GBM method. Since personal prescription period and the severity of comorbidities were considered numerically, individual patients' risk could be well reflected. The prediction model showed high performance and interpretability, so it is meaningful to both clinicians and NSAID users.PMID:37529187 | PMC:PMC10375806 | DOI:10.4055/cios22240 (Source: Clinics in Orthopedic Surgery)
Source: Clinics in Orthopedic Surgery - August 2, 2023 Category: Orthopaedics Authors: Jaehan Jeong Hyein Han Du Hyun Ro Hyuk-Soo Han Sungho Won Source Type: research
