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Nanopore sequencing in distinguishing between wild-type and vaccine strains of Varicella-Zoster virus
CONCLUSION: This study validates that nanopore sequencing is a reliable method for differentiating between the wild-type and vaccine strains of VZV. Its ability to produce long-read sequences is remarkable, allowing simultaneous confirmation of known SNPs and the detection of new mutations. Nanopore sequencing can serve as a valuable tool for the swift and precise identification of wild-type and vaccine strains and has potential applications in future VZV surveillance.PMID:38548526 | DOI:10.1016/j.vaccine.2024.03.046 (Source: Vaccine)
Source: Vaccine - March 28, 2024 Category: Allergy & Immunology Authors: Yuto Fukuda Takako Suzuki Ken-Ichi Iwata Kazunori Haruta Makoto Yamaguchi Yuka Torii Atsushi Narita Hideki Muramatsu Yoshiyuki Takahashi Jun-Ichi Kawada Source Type: research

Nanopore sequencing in distinguishing between wild-type and vaccine strains of Varicella-Zoster virus
CONCLUSION: This study validates that nanopore sequencing is a reliable method for differentiating between the wild-type and vaccine strains of VZV. Its ability to produce long-read sequences is remarkable, allowing simultaneous confirmation of known SNPs and the detection of new mutations. Nanopore sequencing can serve as a valuable tool for the swift and precise identification of wild-type and vaccine strains and has potential applications in future VZV surveillance.PMID:38548526 | DOI:10.1016/j.vaccine.2024.03.046 (Source: Herpes)
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Yuto Fukuda Takako Suzuki Ken-Ichi Iwata Kazunori Haruta Makoto Yamaguchi Yuka Torii Atsushi Narita Hideki Muramatsu Yoshiyuki Takahashi Jun-Ichi Kawada Source Type: research

A Specific Pattern of Routine Cerebrospinal Fluid Parameters Might Help to Identify Cases of West Nile Virus Neuroinvasive Disease
CONCLUSIONS: Cases with WNV ME showed a specific pattern of routine CSF parameters and demographic data that allowed for their identification with good accuracy. These findings might help to guide the diagnostic workup in cases with viral ME, in particular allowing the timely identification of cases with ME due to WNV.PMID:38543707 | PMC:PMC10974314 | DOI:10.3390/v16030341 (Source: Herpes)
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Johann Otto Pelz Christoph M ühlberg Isabel Friedrich Lorenz Weidhase Silke Zimmermann Melanie Maier Corinna Pietsch Source Type: research

Safety and efficacy of magnesium-rich artificial cerebrospinal fluid for subarachnoid hemorrhage
ConclusionUsing MACSF as an irrigation fluid for aneurysm clipping can significantly improve the 90-day prognosis of patients with aSAH, which may be related to the reduced incidence of CVS.Clinical trial registrationhttps://www.clinicaltrials.gov, identifier NCT04358445. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research

Microvascular imaging findings in infants with bacterial meningitis: a case series
AbstractBacterial meningitis is a severe and life-threatening disease that rapidly progresses in neonates and infants; prompt diagnosis and appropriate treatment are lifesaving. Magnetic resonance imaging remains the primary imaging technique for diagnosing meningitis; however, due to its limited availability and cost, ultrasound is often used for initial screening. Microvascular imaging ultrasound (MVI) is an emerging technique that offers insight into the brain microvasculature beyond conventional ultrasound. Here we present three patients with confirmed bacterial meningitis and associated cerebral microvascular findings...
Source: Journal of Ultrasound - March 28, 2024 Category: Radiology Source Type: research

Rapid diagnosis of a case of post-surgical meningitis with BioFire ® Joint Infection Panel
Rev Esp Quimioter. 2024 Mar 27:cuadrado27mar2024. doi: 10.37201/req/009.2024. Online ahead of print.NO ABSTRACTPMID:38533781 | DOI:10.37201/req/009.2024 (Source: Revista Espanola de Quimioterapia)
Source: Revista Espanola de Quimioterapia - March 27, 2024 Category: Drugs & Pharmacology Authors: B Cuadrado Garc ía A Madue ño Alonso A Mart ín Bermúdez L Romero-Acevedo P P érez Orán M Lecuona Fern ández Source Type: research