Research progress on the application of magnesium phosphate bone cement in bone defect repair: A review
CONCLUSION: MPC stands out as an artificial bone substitute with appropriate mechanical strength, rapid degradation, non-toxicity, and good biocompatibility, facilitating bone repair and regeneration. Modification agents can enhance its clinical versatility. Future research should delve into its mechanical properties and formulations, expanding clinical applications to create higher-performing and more medically valuable alternatives in bone defect repair.PMID:38728179 | DOI:10.3233/BME-230164 (Source: Bio-Medical Materials and Engineering)
Source: Bio-Medical Materials and Engineering - May 10, 2024 Category: Materials Science Authors: Yongzheng Tian Ruilong Sun Yunfei Li Peng Liu Bo Fan Yun Xue Source Type: research
Bystander Acknowledgment Mitigates the Psychological and Physiological Pain of Racial Discrimination for Black Young Adults: A Randomized Controlled Trial
In this study we examined whether White bystanders can act to mitigate racism ’s pain sensitizing effects. To simulate racial exclusion in the laboratory, Black young adults (age 18-30; N = 92) were randomly assigned to be included or excluded by White players in a ball-tossing game (Cyberball). For half of excluded participants, White bystanders acknowledged and apologized for the racial exclusion. (Source: The Journal of Pain)
Source: The Journal of Pain - May 10, 2024 Category: Materials Science Authors: Katarina E. AuBuchon, Michelle L. Stock, Vani A Mathur, Brianna Attey, Lisa Bowleg Tags: Original Reports Source Type: research
Catalog of topological phonon materials | Science
Phonons play a crucial role in many properties of solid-state systems, and it is expected that topological phonons may lead to rich and unconventional physics. On the basis of the existing phonon materials databases, we have compiled a catalog of ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 9, 2024 Category: Science Source Type: research
Measurement error, minimal detectable change, and minimal clinically important difference of the Short Form-36 Health Survey, Hospital Anxiety and Depression Scale, and Pain Numeric Rating Scale in patients with chronic pain
This study estimated the standard error of measurement (SEM), one-year minimal detectable change, and one-year minimal clinically important difference (MCID) for the Short Form-36 Health Survey physical component summary (SF-36 PCS) and mental (SF36 MCS), the Hospital Anxiety and Depression Scale anxiety symptoms (HADS-A) and depression symptoms (HADS-D) subscales, and the Numeric Rating Scale (NRS) for past-week average pain intensity. (Source: The Journal of Pain)
Source: The Journal of Pain - May 9, 2024 Category: Materials Science Authors: Rode Gr önkvist, Linda Vixner, Björn Äng, Anna Grimby-Ekman Tags: Original Reports Source Type: research
Serum vitamin D and chronic musculoskeletal pain: a cross-sectional study of 349,221 adults in the UK
Insufficient and deficient vitamin D may be associated with chronic musculoskeletal pain, but study findings are conflicting, and few account for important confounding factors. This cross-sectional study explored the association between serum vitamin D status and chronic musculoskeletal pain in various body sites, adjusting for a wide range and number of potential confounding factors. Data collected at the baseline assessments of 349,221 UK Biobank participants between 2006 and 2010 were analysed. (Source: The Journal of Pain)
Source: The Journal of Pain - May 9, 2024 Category: Materials Science Authors: Yanfei Xie, Scott F Farrell, Nigel Armfield, Michele Sterling Source Type: research
Two-dimensional carbon/boron nitrides: modification, machine learning and beyond
J. Mater. Chem. A, 2024, Accepted Manuscript DOI: 10.1039/D4TA02059F, Review ArticleQi Wu, Yangrui Lin, Yangwenting Ou, changhua wang, Rui Wang, He Ma, Yuanyuan Li, Xintong Zhang The exploration and functionalization of two-dimensional (2D) materials have opened new horizons in the fields of catalysis and materials science. Therein, 2D non-metallic nitrides have attracted significant attention due to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)
Source: RSC - J. Mater. Chem. latest articles - May 8, 2024 Category: Chemistry Authors: Qi Wu Source Type: research
Effect of gastric acids on the mechanical properties of conventional and CAD/CAM resin composites - An in-vitro study
CONCLUSION: Conventional RBCs might show greater reduction in mechanical properties compared to CAD/CAM RBCs when exposed to gastric acid attack. Thus, CAD/CAM composites may represent a suitable choice for the treatment of patients presenting erosive issues.PMID:38718723 | DOI:10.1016/j.jmbbm.2024.106565 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 8, 2024 Category: Materials Science Authors: Alexandra Gil-Pozo Daniela Astudillo-Rubio Álvaro Ferrando Cascales Francesco Inchingolo Ronaldo Hirata Salvatore Sauro Andr és Delgado-Gaete Source Type: research
Co-delivery of Plinabulin and Tirapazamine boosts anti-tumor efficacy by simultaneously destroying tumor blood vessels and killing tumor cells
In this study, we employed methoxy poly(ethylene glycol)-b-poly(D,L-lactide) (mPEG-b-PDLLA) to co-deliver Plinabulin and TPZ to the tumor site, concurrently disrupting blood vessels and eliminating tumor cells, addressing both symptoms and the root cause of tumor progression. Plinabulin was converted into a prodrug with esterase response (PSM), and TPZ was synthesized into a hexyl chain-containing derivative (TPZHex) for effective co-delivery. PSM and TPZHex were co-encapsulated with mPEG-b-PDLLA, forming nanodrugs (PT-NPs). At the tumor site, PT-NPs responded to esterase overexpression, releasing Plinabulin, disrupting bl...
Source: Biomaterials - May 8, 2024 Category: Materials Science Authors: Jianlin Lv Yajun Xu Ya Liu Kazuo Sakurai Haiyang Yu Zhaohui Tang Source Type: research
3D-Printed proangiogenic patches of photo-crosslinked gelatin and polyurethane hydrogels laden with vascular cells for treating vascular ischemic diseases
Biomaterials. 2024 Apr 30;309:122600. doi: 10.1016/j.biomaterials.2024.122600. Online ahead of print.ABSTRACTEngineering vascularized tissues remains a promising approach for treating ischemic cardiovascular diseases. The availability of 3D-bioprinted vascular grafts that induce therapeutic angiogenesis can help avoid necrosis and excision of ischemic tissues. Here, using a combination of living cells and biodegradable hydrogels, we fabricated 3D-printed biocompatible proangiogenic patches from endothelial cell-laden photo-crosslinked gelatin (EC-PCG) bioink and smooth muscle cell-encapsulated polyurethane (SMC-PU) bioink....
Source: Biomaterials - May 8, 2024 Category: Materials Science Authors: Yu-Tsung Shih Kun-Chih Cheng Yi-Ju Ko Chia-Yu Lin Mei-Cun Wang Chih-I Lee Pei-Ling Lee Rong Qi Jeng-Jiann Chiu Shan-Hui Hsu Source Type: research
Co-delivery of Plinabulin and Tirapazamine boosts anti-tumor efficacy by simultaneously destroying tumor blood vessels and killing tumor cells
In this study, we employed methoxy poly(ethylene glycol)-b-poly(D,L-lactide) (mPEG-b-PDLLA) to co-deliver Plinabulin and TPZ to the tumor site, concurrently disrupting blood vessels and eliminating tumor cells, addressing both symptoms and the root cause of tumor progression. Plinabulin was converted into a prodrug with esterase response (PSM), and TPZ was synthesized into a hexyl chain-containing derivative (TPZHex) for effective co-delivery. PSM and TPZHex were co-encapsulated with mPEG-b-PDLLA, forming nanodrugs (PT-NPs). At the tumor site, PT-NPs responded to esterase overexpression, releasing Plinabulin, disrupting bl...
Source: Biomaterials - May 8, 2024 Category: Materials Science Authors: Jianlin Lv Yajun Xu Ya Liu Kazuo Sakurai Haiyang Yu Zhaohui Tang Source Type: research
3D-Printed proangiogenic patches of photo-crosslinked gelatin and polyurethane hydrogels laden with vascular cells for treating vascular ischemic diseases
Biomaterials. 2024 Apr 30;309:122600. doi: 10.1016/j.biomaterials.2024.122600. Online ahead of print.ABSTRACTEngineering vascularized tissues remains a promising approach for treating ischemic cardiovascular diseases. The availability of 3D-bioprinted vascular grafts that induce therapeutic angiogenesis can help avoid necrosis and excision of ischemic tissues. Here, using a combination of living cells and biodegradable hydrogels, we fabricated 3D-printed biocompatible proangiogenic patches from endothelial cell-laden photo-crosslinked gelatin (EC-PCG) bioink and smooth muscle cell-encapsulated polyurethane (SMC-PU) bioink....
Source: Biomaterials - May 8, 2024 Category: Materials Science Authors: Yu-Tsung Shih Kun-Chih Cheng Yi-Ju Ko Chia-Yu Lin Mei-Cun Wang Chih-I Lee Pei-Ling Lee Rong Qi Jeng-Jiann Chiu Shan-Hui Hsu Source Type: research
Effect of gastric acids on the mechanical properties of conventional and CAD/CAM resin composites - An in-vitro study
CONCLUSION: Conventional RBCs might show greater reduction in mechanical properties compared to CAD/CAM RBCs when exposed to gastric acid attack. Thus, CAD/CAM composites may represent a suitable choice for the treatment of patients presenting erosive issues.PMID:38718723 | DOI:10.1016/j.jmbbm.2024.106565 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 8, 2024 Category: Materials Science Authors: Alexandra Gil-Pozo Daniela Astudillo-Rubio Álvaro Ferrando Cascales Francesco Inchingolo Ronaldo Hirata Salvatore Sauro Andr és Delgado-Gaete Source Type: research
Effect of gastric acids on the mechanical properties of conventional and CAD/CAM resin composites - An in-vitro study
CONCLUSION: Conventional RBCs might show greater reduction in mechanical properties compared to CAD/CAM RBCs when exposed to gastric acid attack. Thus, CAD/CAM composites may represent a suitable choice for the treatment of patients presenting erosive issues.PMID:38718723 | DOI:10.1016/j.jmbbm.2024.106565 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - May 8, 2024 Category: Materials Science Authors: Alexandra Gil-Pozo Daniela Astudillo-Rubio Álvaro Ferrando Cascales Francesco Inchingolo Ronaldo Hirata Salvatore Sauro Andr és Delgado-Gaete Source Type: research
Co-delivery of Plinabulin and Tirapazamine boosts anti-tumor efficacy by simultaneously destroying tumor blood vessels and killing tumor cells
In this study, we employed methoxy poly(ethylene glycol)-b-poly(D,L-lactide) (mPEG-b-PDLLA) to co-deliver Plinabulin and TPZ to the tumor site, concurrently disrupting blood vessels and eliminating tumor cells, addressing both symptoms and the root cause of tumor progression. Plinabulin was converted into a prodrug with esterase response (PSM), and TPZ was synthesized into a hexyl chain-containing derivative (TPZHex) for effective co-delivery. PSM and TPZHex were co-encapsulated with mPEG-b-PDLLA, forming nanodrugs (PT-NPs). At the tumor site, PT-NPs responded to esterase overexpression, releasing Plinabulin, disrupting bl...
Source: Biomaterials - May 8, 2024 Category: Materials Science Authors: Jianlin Lv Yajun Xu Ya Liu Kazuo Sakurai Haiyang Yu Zhaohui Tang Source Type: research
3D-Printed proangiogenic patches of photo-crosslinked gelatin and polyurethane hydrogels laden with vascular cells for treating vascular ischemic diseases
Biomaterials. 2024 Apr 30;309:122600. doi: 10.1016/j.biomaterials.2024.122600. Online ahead of print.ABSTRACTEngineering vascularized tissues remains a promising approach for treating ischemic cardiovascular diseases. The availability of 3D-bioprinted vascular grafts that induce therapeutic angiogenesis can help avoid necrosis and excision of ischemic tissues. Here, using a combination of living cells and biodegradable hydrogels, we fabricated 3D-printed biocompatible proangiogenic patches from endothelial cell-laden photo-crosslinked gelatin (EC-PCG) bioink and smooth muscle cell-encapsulated polyurethane (SMC-PU) bioink....
Source: Biomaterials - May 8, 2024 Category: Materials Science Authors: Yu-Tsung Shih Kun-Chih Cheng Yi-Ju Ko Chia-Yu Lin Mei-Cun Wang Chih-I Lee Pei-Ling Lee Rong Qi Jeng-Jiann Chiu Shan-Hui Hsu Source Type: research
