Interferon- γ and infectious diseases: Lessons and prospects | Science
Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from these diseases would benefit not just from new medicines and vaccines but also from a better understanding of what constitutes protective immunity. Among the ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Phage predation, disease severity, and pathogen genetic diversity in cholera patients | Science
Despite an increasingly detailed picture of the molecular mechanisms of bacteriophage (phage) –bacterial interactions, we lack an understanding of how these interactions evolve and impact disease within patients. In this work, we report a year-long, ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need | Science
Drugs of abuse are thought to promote addiction in part by “hijacking” brain reward systems, but the underlying mechanisms remain undefined. Using whole-brain FOS mapping and in vivo single-neuron calcium imaging, we found that drugs of abuse augment ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

A naturally isolated symbiotic bacterium suppresses flavivirus transmission by Aedes mosquitoes | Science
In this study, we identified a bacterium from the gut of field Aedes albopictus mosquitoes named Rosenbergiella sp. YN46 (... (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

France needs a chief science adviser | Science
France is at a crossroads, facing environmental and social challenges that are profoundly altering its society. Yet, the French government keeps prioritizing short-term political gains over long-term evidence-based planning for major transitions that ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Earth ’s sinking surface | Science
China ’s major cities show considerable subsidence from human activities (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Sentinels of the airways | Science
Epithelial cells in the larynx and trachea sense harmful cues and trigger protective reflexes (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Reprioritizing motivations in addiction | Science
Drugs of abuse alter neuronal signaling (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Exposing belowground plant communication | Science
Root exudation could be harnessed for ecological and applied research (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Sir Michael Anthony Epstein (1921 –2024) | Science
Codiscoverer of the Epstein-Barr virus (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Developing transmissible vaccines for animal infections | Science
Intrinsically safe designs and a staged transparent development process will be essential (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Imagining other worlds | Science
An astronomer offers a vivid portrait of exoplanet landscapes (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Centering Earth in policy-making | Science
A pair of authors advocate scaling governance structures to better address planetary crises (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Link circular economy to waste hierarchy in treaty | Science
HomeScienceVol. 384, No. 6693Link circular economy to waste hierarchy in treatyBack To Vol. 384, No. 6693 Full accessLetter Share on Link circular economy to waste hierarchy in treatyKristian Syberg [email  protected], Nikoline G. Oturai, [...] , Steffen Foss Hansen, Terrence J. Collins, [...] , Sedat Gündoğdu, Bethanie Carney Almroth, Ellen Palm, Arturo Castillo Castillo, Juan Baztan, [...] , Nat… (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research

Global plastics treaty needs trusted science | Science
Discussions will include the negotiation of a scientific body that will set goals and monitor progress. To ensure unbiased, evidence-based decisions about the future of plastics, a science body with a robust policy on conflict of interest is needed. (Source: Science: Current Issue)
Source: Science: Current Issue - April 18, 2024 Category: Science Source Type: research