Nextgen Voices: Preventing Bad Behavior | Science
Add your voice to Science! Our new NextGen Voices survey is now open: What one change to scientifi c policy or culture would substantially decrease incidents of scientifi c misconduct or other unethical behavior? (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Protect Pakistan ’s otters | Science
Pakistan is home to two otter species, the Eurasian otter (Lutra lutra) and the smooth-coated otter (Lutrogale perspicillata). Two decades ago, these species thrived in habitats across Pakistan, but now they are limited to isolated patches in their range (1), are classified as Near Threatened in Pakistan (2), and are listed in Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) (3). Pakistan must take steps to protect otters. (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Noncharismatic species also need protection | Science
Global biodiversity decline is a pressing environmental challenge in the 21st century (1), and both international platforms, such as the United Nations Conference of the Parties (2), and regional development plans [e.g., (3)] focus on biodiversity conservation. However, because of the public appeal of charismatic species, research resources are predominantly invested in birds and mammals (4) and often exclude noncharismatic species, such as fish, insects, and plants. Contrary to perceptions, the ecological and economic consequences of noncharismatic species are often substantial. Researchers must study noncharismatic speci...
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

In Science Journals | Science
Highlights from the Science family of journals (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

In Other Journals | Science
Editors ’ selections from the current scientific literature (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Locally narrow droplet size distributions are ubiquitous in stratocumulus clouds | Science
Marine stratocumulus clouds are the “global reflectors,” sharply contrasting with the underlying dark ocean surface and exerting a net cooling on Earth’s climate. The magnitude of this cooling remains uncertain in part owing to the averaged ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

A pandemic agreement is within reach | Science
At the end of May, 194 member states of the World Health Organization (WHO) will meet for the World Health Assembly. Negotiations underway now will determine whether they vote then to adopt a pandemic agreement. For the past 2 years, discussions have ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 30, 2024 Category: Science Source Type: research

Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules | Science
Tubulin, one of the most abundant cytoskeletal building blocks, has numerous isotypes in metazoans encoded by different conserved genes. Whether these distinct isotypes form cell type – and context-specific microtubule structures is poorly understood. ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 26, 2024 Category: Science Source Type: research

Sequence basis of transcription initiation in the human genome | Science
Transcription initiation is a process that is essential to ensuring the proper function of any gene, yet we still lack a unified understanding of sequence patterns and rules that explain most transcription start sites in the human genome. By predicting ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 26, 2024 Category: Science Source Type: research

Genomic factors shape carbon and nitrogen metabolic niche breadth across Saccharomycotina yeasts | Science
Organisms exhibit extensive variation in ecological niche breadth, from very narrow (specialists) to very broad (generalists). Two general paradigms have been proposed to explain this variation: (i) trade-offs between performance efficiency and breadth ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 26, 2024 Category: Science Source Type: research

Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells | Science
Chemical modulation of proteins enables a mechanistic understanding of biology and represents the foundation of most therapeutics. However, despite decades of research, 80% of the human proteome lacks functional ligands. Chemical proteomics has advanced ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 26, 2024 Category: Science Source Type: research

Science needs neurodiversity | Science
All brains work differently. Individuals process information and engage with the world in ways that are influenced by a multitude of biological, cultural, and social factors. In the world of science, these differences are what spark innovation. This is ... (Source: Science: Current Issue)
Source: Science: Current Issue - April 25, 2024 Category: Science Source Type: research

A sound beginning of life starts before birth | Science
Long-term impact from prenatal noise exposure in birds should raise general concern (Source: Science: Current Issue)
Source: Science: Current Issue - April 25, 2024 Category: Science Source Type: research

How DNA encodes the start of transcription | Science
A deep-learning model reveals the rules that define transcription initiation (Source: Science: Current Issue)
Source: Science: Current Issue - April 25, 2024 Category: Science Source Type: research

Microbes and vitamin D aid immunotherapy | Science
Vitamin D modulates intestinal epithelial cell function to enhance antitumor microbes (Source: Science: Current Issue)
Source: Science: Current Issue - April 25, 2024 Category: Science Source Type: research