Hepatic glycogenesis antagonizes lipogenesis by blocking S1P via UDPG | Science
The glycogenesis metabolite UDPG antagonizes lipogenesis and promotes storage of glucose carbon as glycogen in hepatocytes. (Source: Science: Current Issue)
Source: Science: Current Issue - February 16, 2024 Category: Science Source Type: research

Paired plant immune CHS3-CSA1 receptor alleles form distinct hetero-oligomeric complexes | Science
Pairs of intracellular immune receptors heterodimerize and oligomerize to activate immunity in plants. (Source: Science: Current Issue)
Source: Science: Current Issue - February 16, 2024 Category: Science Source Type: research

Science communication at scale | Science
On the television program MythBusters, which aired on the Discovery Channel from 2003 to 2016, the hosts Adam Savage and Jamie Hyneman tested popular myths and ideas arising everywhere from folklore to popular culture, designating them as either “busted” ... (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Conflation of reforestation with restoration is widespread | Science
Across Africa, vast areas of nonforest are threatened by inappropriate restoration in the form of tree planting (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Telomerase misbehaves after a breakup | Science
Suppressing telomerase action at broken DNA preserves genome integrity (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

HIV cure: The daunting scale of the problem | Science
Cure strategies are confounded by basic reservoir biology (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Decoding the autoantibody reactome | Science
Autoantibodies influence a wide range of conditions beyond autoimmune diseases (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Mixed-organism enzyme in plant defense | Science
Plants commandeer a pathogen ’s virulence factor to bolster immunity (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

The end of the auk | Science
An anthropologist recounts how a pair of 19th-century naturalists traced an elusive bird ’s extinction in real time (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Managing expectations | Science
A political scientist urges readers to embrace the chaos and complexity of life (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Fund two extremely large US telescopes | Science
HomeScienceVol. 383, No. 6684Fund two extremely large US telescopesBack To Vol. 383, No. 6684 Full accessLetter Share on Fund two extremely large US telescopesPatrick McCarthy, Robert P. Kirshner [email  protected], and Robert N. SheltonAuthors Info& AffiliationsScience15 Feb 2024Vol 383, Issue 6684p. 711DOI: 10.1126/science.adn7832 PREVIOUS ARTICLEManaging expectationsPreviousNEXT ARTICLEFlorida … (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Florida law undercuts US leadership in science | Science
In his In Depth story “Florida law blocks hiring of Chinese students” (15 December 2023, p. 1220), J. Mervis describes Florida’s SB 846 (1), which hinders and potentially prohibits hiring applicants from China or six other “countries of concern” unless the university obtains a waiver from the state (2). Any sta te’s decision to shut out international scholars will push talented individuals elsewhere, cause delays in existing research efforts, threaten local job growth potential, and endanger US global leadership in research and development. (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Ethical treatment of Iran ’s research animals | Science
Globally, about 192.1 million animals are used annually for experimental purposes and testing (1). Iran has conducted animalbased research dating back to the time of Ibn Sina (2). Although, like many countries, Iran regulates the use and treatment of laboratory animals, it lacks sufficient enforcement. To ensure ethical treatment of research animals, Iran needs better data about their use, and institutions and individuals need to take responsibility for their care. (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Protons are the new first responders | Science
Human STING ’s newfound function as a channel expands our understanding of immunity (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research

Stem cells in disguise | Science
Epitope editing can empower targeted cancer immunotherapies (Source: Science: Current Issue)
Source: Science: Current Issue - February 15, 2024 Category: Science Source Type: research