Influence of additives and binder on the physical properties of dental silicate glass-ceramic feedstock for additive manufacturing
J Mech Behav Biomed Mater. 2024 Apr 25;155:106563. doi: 10.1016/j.jmbbm.2024.106563. Online ahead of print.ABSTRACTOBJECTIVES: The aim of the study was to investigate the impact of organic additives (binder, plasticizer, and the cross-linking ink) in the formulation of water-based feedstocks on the properties of a dental feldspathic glass-ceramic material developed for the slurry-based additive manufacturing technology "LSD-print."MATERIAL AND METHODS: Three water-based feldspathic feedstocks were produced to study the effects of polyvinyl alcohol (AC1) and poly (sodium 4-styrenesulfonate) (AC2) as binder systems. A feedst...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Moritz Hoffmann Bogna Stawarczyk Jens G ünster Andrea Zocca Source Type: research
Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in thoroughbred racehorses elevates site-specific strain concentration
J Mech Behav Biomed Mater. 2024 Apr 24;155:106561. doi: 10.1016/j.jmbbm.2024.106561. Online ahead of print.ABSTRACTCondylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Soroush Irandoust R Christopher Whitton Peter Muir Corinne R Henak Source Type: research
Studying the nonlinear response of incompressible hyperelastic thin circular cylindrical shells with geometric imperfections
This study presents a comprehensive analysis of hyperelastic thin cylindrical shells exhibiting initial geometrical imperfections. The nonlinear equations of motion are derived using an improved formulation of Donnell's nonlinear shallow-shell theory and Lagrange's equations, incorporating the small strain hypothesis. Mooney-Rivlin constitutive model is employed to capture the hyperelastic behavior of the material. The coupled nonlinear equations of motion are analytically solved using Multiple-Scale method, which effectively accounts for the inherent nonlinearity of the system. To ensure the model's accuracy, the linear m...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Morteza Shayan Arani Mehrdad Bakhtiari Mohammad Toorani Aouni A Lakis Source Type: research
Trehalose enhanced cold atmospheric plasma-mediated cancer treatment
Biomaterials. 2024 Apr 18;309:122582. doi: 10.1016/j.biomaterials.2024.122582. Online ahead of print.ABSTRACTCold atmospheric plasma (CAP) is a unique form of physical plasma that has shown great potential for cancer therapy. CAP uses ionized gas to induce lethal oxidative stress on cancer cells; however, the efficacy of CAP therapy continues to be improved. Here, we report an injectable hydrogel-mediated approach to enhance the anti-tumor efficacy of CAP by regulating the phosphorylation of eIF2α. We discovered that reactive oxygen and nitrogen species (ROS/RNS), two main anti-tumor components in CAP, can lead to lethal ...
Source: Biomaterials - April 28, 2024 Category: Materials Science Authors: Xiaona Cao Tianxu Fang Mo Chen Tianqin Ning Jianyu Li Peter M Siegel Morag Park Zhitong Chen Guojun Chen Source Type: research
Studying the nonlinear response of incompressible hyperelastic thin circular cylindrical shells with geometric imperfections
This study presents a comprehensive analysis of hyperelastic thin cylindrical shells exhibiting initial geometrical imperfections. The nonlinear equations of motion are derived using an improved formulation of Donnell's nonlinear shallow-shell theory and Lagrange's equations, incorporating the small strain hypothesis. Mooney-Rivlin constitutive model is employed to capture the hyperelastic behavior of the material. The coupled nonlinear equations of motion are analytically solved using Multiple-Scale method, which effectively accounts for the inherent nonlinearity of the system. To ensure the model's accuracy, the linear m...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Morteza Shayan Arani Mehrdad Bakhtiari Mohammad Toorani Aouni A Lakis Source Type: research
Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in thoroughbred racehorses elevates site-specific strain concentration
J Mech Behav Biomed Mater. 2024 Apr 24;155:106561. doi: 10.1016/j.jmbbm.2024.106561. Online ahead of print.ABSTRACTCondylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Soroush Irandoust R Christopher Whitton Peter Muir Corinne R Henak Source Type: research
Influence of additives and binder on the physical properties of dental silicate glass-ceramic feedstock for additive manufacturing
J Mech Behav Biomed Mater. 2024 Apr 25;155:106563. doi: 10.1016/j.jmbbm.2024.106563. Online ahead of print.ABSTRACTOBJECTIVES: The aim of the study was to investigate the impact of organic additives (binder, plasticizer, and the cross-linking ink) in the formulation of water-based feedstocks on the properties of a dental feldspathic glass-ceramic material developed for the slurry-based additive manufacturing technology "LSD-print."MATERIAL AND METHODS: Three water-based feldspathic feedstocks were produced to study the effects of polyvinyl alcohol (AC1) and poly (sodium 4-styrenesulfonate) (AC2) as binder systems. A feedst...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Moritz Hoffmann Bogna Stawarczyk Jens G ünster Andrea Zocca Source Type: research
Approach for contact medical device development via integrated testing, skeletal muscle modeling, and finite element analysis
J Mech Behav Biomed Mater. 2024 Apr 16;155:106541. doi: 10.1016/j.jmbbm.2024.106541. Online ahead of print.ABSTRACTDevelopment of novel medical devices for the treatment of musculoskeletal pain associated with neuro-muscular trigger points requires a model for relating the mechanical responses of in vivo biological tissues to applied palliative physical pressures and a method to design treatments for optimal effects. It is reasonable to hypothesize that the efficacy of therapeutic treatment is proportional to the maximum tensile strain at trigger point locations. This work presents modeling of the mechanical behavior of bi...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Conor Shanley Q Jane Wang Bruce Livingston Source Type: research
Trehalose enhanced cold atmospheric plasma-mediated cancer treatment
Biomaterials. 2024 Apr 18;309:122582. doi: 10.1016/j.biomaterials.2024.122582. Online ahead of print.ABSTRACTCold atmospheric plasma (CAP) is a unique form of physical plasma that has shown great potential for cancer therapy. CAP uses ionized gas to induce lethal oxidative stress on cancer cells; however, the efficacy of CAP therapy continues to be improved. Here, we report an injectable hydrogel-mediated approach to enhance the anti-tumor efficacy of CAP by regulating the phosphorylation of eIF2α. We discovered that reactive oxygen and nitrogen species (ROS/RNS), two main anti-tumor components in CAP, can lead to lethal ...
Source: Biomaterials - April 28, 2024 Category: Materials Science Authors: Xiaona Cao Tianxu Fang Mo Chen Tianqin Ning Jianyu Li Peter M Siegel Morag Park Zhitong Chen Guojun Chen Source Type: research
Influence of additives and binder on the physical properties of dental silicate glass-ceramic feedstock for additive manufacturing
J Mech Behav Biomed Mater. 2024 Apr 25;155:106563. doi: 10.1016/j.jmbbm.2024.106563. Online ahead of print.ABSTRACTOBJECTIVES: The aim of the study was to investigate the impact of organic additives (binder, plasticizer, and the cross-linking ink) in the formulation of water-based feedstocks on the properties of a dental feldspathic glass-ceramic material developed for the slurry-based additive manufacturing technology "LSD-print."MATERIAL AND METHODS: Three water-based feldspathic feedstocks were produced to study the effects of polyvinyl alcohol (AC1) and poly (sodium 4-styrenesulfonate) (AC2) as binder systems. A feedst...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Moritz Hoffmann Bogna Stawarczyk Jens G ünster Andrea Zocca Source Type: research
Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in thoroughbred racehorses elevates site-specific strain concentration
J Mech Behav Biomed Mater. 2024 Apr 24;155:106561. doi: 10.1016/j.jmbbm.2024.106561. Online ahead of print.ABSTRACTCondylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Soroush Irandoust R Christopher Whitton Peter Muir Corinne R Henak Source Type: research
Studying the nonlinear response of incompressible hyperelastic thin circular cylindrical shells with geometric imperfections
This study presents a comprehensive analysis of hyperelastic thin cylindrical shells exhibiting initial geometrical imperfections. The nonlinear equations of motion are derived using an improved formulation of Donnell's nonlinear shallow-shell theory and Lagrange's equations, incorporating the small strain hypothesis. Mooney-Rivlin constitutive model is employed to capture the hyperelastic behavior of the material. The coupled nonlinear equations of motion are analytically solved using Multiple-Scale method, which effectively accounts for the inherent nonlinearity of the system. To ensure the model's accuracy, the linear m...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Morteza Shayan Arani Mehrdad Bakhtiari Mohammad Toorani Aouni A Lakis Source Type: research
Approach for contact medical device development via integrated testing, skeletal muscle modeling, and finite element analysis
J Mech Behav Biomed Mater. 2024 Apr 16;155:106541. doi: 10.1016/j.jmbbm.2024.106541. Online ahead of print.ABSTRACTDevelopment of novel medical devices for the treatment of musculoskeletal pain associated with neuro-muscular trigger points requires a model for relating the mechanical responses of in vivo biological tissues to applied palliative physical pressures and a method to design treatments for optimal effects. It is reasonable to hypothesize that the efficacy of therapeutic treatment is proportional to the maximum tensile strain at trigger point locations. This work presents modeling of the mechanical behavior of bi...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Conor Shanley Q Jane Wang Bruce Livingston Source Type: research
Studying the nonlinear response of incompressible hyperelastic thin circular cylindrical shells with geometric imperfections
This study presents a comprehensive analysis of hyperelastic thin cylindrical shells exhibiting initial geometrical imperfections. The nonlinear equations of motion are derived using an improved formulation of Donnell's nonlinear shallow-shell theory and Lagrange's equations, incorporating the small strain hypothesis. Mooney-Rivlin constitutive model is employed to capture the hyperelastic behavior of the material. The coupled nonlinear equations of motion are analytically solved using Multiple-Scale method, which effectively accounts for the inherent nonlinearity of the system. To ensure the model's accuracy, the linear m...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Morteza Shayan Arani Mehrdad Bakhtiari Mohammad Toorani Aouni A Lakis Source Type: research
Subchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in thoroughbred racehorses elevates site-specific strain concentration
J Mech Behav Biomed Mater. 2024 Apr 24;155:106561. doi: 10.1016/j.jmbbm.2024.106561. Online ahead of print.ABSTRACTCondylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed...
Source: Journal of the Mechanical Behavior of Biomedical Materials - April 28, 2024 Category: Materials Science Authors: Soroush Irandoust R Christopher Whitton Peter Muir Corinne R Henak Source Type: research
