Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Inhibition of plant essential oils and their interaction in binary combinations against tyrosinase
CONCLUSION: It is revealed that natural EOs would be promising to be effective anti-tyrosinase agents, and binary combinations of cinnamon, bay, and magnolia officinalis might not have synergistic effects on tyrosinase under certain condition.PMID:36590855 | PMC:PMC9793764 | DOI:10.29219/fnr.v66.8466 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - January 2, 2023 Category: Nutrition Authors: Zonglin You Yonglian Li Min Chen Vincent Kam Wai Wong Kun Zhang Xi Zheng Wenfeng Liu Source Type: research
Semisynthesis, biological activities, and mechanism studies of Mannich base analogues of magnolol/honokiol as potential α-glucosidase inhibitors
Bioorg Med Chem. 2022 Oct 22;75:117070. doi: 10.1016/j.bmc.2022.117070. Online ahead of print.ABSTRACTMagnolol and honokiol, derived from a Magnolia officinalis Rehd. et Wils, are a class of natural biphenolic lignans. Currently, the discovery of new α-glucosidase inhibitors from natural analogues is of interest. Here, four series of thirty new Mannich base analogues of magnolol/honokiol were prepared and evaluated for their α-glucosidase inhibitory activities. Among these Mannich base analogues of magnolol/honokiol, 3k and 3l exhibited more potent inhibitory effects on α-glucosidase than the reference drug acarbose, an...
Source: Bioorganic and Medicinal Chemistry - November 3, 2022 Category: Chemistry Authors: Junyan Chu Ruige Yang Wanqing Cheng Liping Cui Hanchen Pan Jifeng Liu Yong Guo Source Type: research
Semisynthesis, biological activities, and mechanism studies of Mannich base analogues of magnolol/honokiol as potential α-glucosidase inhibitors
Bioorg Med Chem. 2022 Oct 22;75:117070. doi: 10.1016/j.bmc.2022.117070. Online ahead of print.ABSTRACTMagnolol and honokiol, derived from a Magnolia officinalis Rehd. et Wils, are a class of natural biphenolic lignans. Currently, the discovery of new α-glucosidase inhibitors from natural analogues is of interest. Here, four series of thirty new Mannich base analogues of magnolol/honokiol were prepared and evaluated for their α-glucosidase inhibitory activities. Among these Mannich base analogues of magnolol/honokiol, 3k and 3l exhibited more potent inhibitory effects on α-glucosidase than the reference drug acarbose, an...
Source: Bioorganic and Medicinal Chemistry - November 3, 2022 Category: Chemistry Authors: Junyan Chu Ruige Yang Wanqing Cheng Liping Cui Hanchen Pan Jifeng Liu Yong Guo Source Type: research
Transcriptomic analysis shows the antifungal mechanism of honokiol against Aspergillus flavus
In this study, honokiol, a type of phenolic compound in Magnolia officinalis, was found to inhibit spore germination and mycelia growth of Aspergillus flavus at 100 μg/mL. In addition, a pathogenicity assay showed that honokiol had potent antifungal activity against A. flavus in corn flour by suppressing conidia production. Fluorescence staining, transmission electron microscopy and biochemical assays were performed to explore its possible inhibition mechanisms against A. flavus. The results showed that the destructive effect of honokiol on A. flavus appeared to be related to increased plasma membrane permeability, the in...
Source: International Journal of Food Microbiology - October 24, 2022 Category: Food Science Authors: Wei Zhang Bangbang Li Yangyong Lv Shan Wei Shuaibing Zhang Yuansen Hu Source Type: research
Transcriptomic analysis shows the antifungal mechanism of honokiol against Aspergillus flavus
In this study, honokiol, a type of phenolic compound in Magnolia officinalis, was found to inhibit spore germination and mycelia growth of Aspergillus flavus at 100 μg/mL. In addition, a pathogenicity assay showed that honokiol had potent antifungal activity against A. flavus in corn flour by suppressing conidia production. Fluorescence staining, transmission electron microscopy and biochemical assays were performed to explore its possible inhibition mechanisms against A. flavus. The results showed that the destructive effect of honokiol on A. flavus appeared to be related to increased plasma membrane permeability, the in...
Source: International Journal of Food Microbiology - October 24, 2022 Category: Food Science Authors: Wei Zhang Bangbang Li Yangyong Lv Shan Wei Shuaibing Zhang Yuansen Hu Source Type: research
Transcriptomic analysis shows the antifungal mechanism of honokiol against Aspergillus flavus
In this study, honokiol, a type of phenolic compound in Magnolia officinalis, was found to inhibit spore germination and mycelia growth of Aspergillus flavus at 100 μg/mL. In addition, a pathogenicity assay showed that honokiol had potent antifungal activity against A. flavus in corn flour by suppressing conidia production. Fluorescence staining, transmission electron microscopy and biochemical assays were performed to explore its possible inhibition mechanisms against A. flavus. The results showed that the destructive effect of honokiol on A. flavus appeared to be related to increased plasma membrane permeability, the in...
Source: International Journal of Food Microbiology - October 24, 2022 Category: Food Science Authors: Wei Zhang Bangbang Li Yangyong Lv Shan Wei Shuaibing Zhang Yuansen Hu Source Type: research
Transcriptomic analysis shows the antifungal mechanism of honokiol against Aspergillus flavus
In this study, honokiol, a type of phenolic compound in Magnolia officinalis, was found to inhibit spore germination and mycelia growth of Aspergillus flavus at 100 μg/mL. In addition, a pathogenicity assay showed that honokiol had potent antifungal activity against A. flavus in corn flour by suppressing conidia production. Fluorescence staining, transmission electron microscopy and biochemical assays were performed to explore its possible inhibition mechanisms against A. flavus. The results showed that the destructive effect of honokiol on A. flavus appeared to be related to increased plasma membrane permeability, the in...
Source: International Journal of Food Microbiology - October 24, 2022 Category: Food Science Authors: Wei Zhang Bangbang Li Yangyong Lv Shan Wei Shuaibing Zhang Yuansen Hu Source Type: research
