Investigating the effect of hesperetin on estrogen receptor alpha (ER α) expression, phosphorylation and activity in MCF-7 cells
CONCLUSION: Based on the results of this study, it can be concluded that hesperetin has a significant effect on ERα expression, phosphorylation and activity.PMID:38462023 | DOI:10.1016/j.gene.2024.148357 (Source: Gene)
Source: Gene - March 10, 2024 Category: Genetics & Stem Cells Authors: Ramin Vosooghi Alireza Motavalizadehkakhky Atena Mansouri Jamshid Mehrzad Masood Homayouni Source Type: research

Investigating the effect of hesperetin on estrogen receptor alpha (ER α) expression, phosphorylation and activity in MCF-7 cells
CONCLUSION: Based on the results of this study, it can be concluded that hesperetin has a significant effect on ERα expression, phosphorylation and activity.PMID:38462023 | DOI:10.1016/j.gene.2024.148357 (Source: Gene)
Source: Gene - March 10, 2024 Category: Genetics & Stem Cells Authors: Ramin Vosooghi Alireza Motavalizadehkakhky Atena Mansouri Jamshid Mehrzad Masood Homayouni Source Type: research

Bioaccumulation of metals in Spartina alterniflora salt marshes in the estuary of the World's Largest Choked Lagoon
This study investigates the influence of different anthropogenic activities, including industrial, urban, recreational (in an insular area), and dredging operations, on the bioaccumulation of eight metals (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) within Spartina alterniflora Loisel. in the Patos Lagoon estuary, Brazil. The research aims to assess the pattern of metal bioaccumulation and distribution within the plant's leaves, stems, and roots while also examining metal presence in the sediment. Our main findings reveal that S. alterniflora exhibited elevated metal levels in its plant structure directly related with the metal co...
Source: Environmental Science and Pollution Research International - March 8, 2024 Category: Environmental Health Authors: Laura Lemons Moreira Ronan Adler Tavella Alicia da Silva Bonif ácio Rodrigo de Lima Brum Livia da Silva Freitas Niely Gale ão da Rosa Moraes Maria Laura Fiasconaro Paula Florencio Ramires Julia Oliveira Penteado Paulo Roberto Martins Baisch Flavio Manoe Source Type: research

Bioaccumulation of metals in Spartina alterniflora salt marshes in the estuary of the World's Largest Choked Lagoon
This study investigates the influence of different anthropogenic activities, including industrial, urban, recreational (in an insular area), and dredging operations, on the bioaccumulation of eight metals (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) within Spartina alterniflora Loisel. in the Patos Lagoon estuary, Brazil. The research aims to assess the pattern of metal bioaccumulation and distribution within the plant's leaves, stems, and roots while also examining metal presence in the sediment. Our main findings reveal that S. alterniflora exhibited elevated metal levels in its plant structure directly related with the metal co...
Source: Environmental Science and Pollution Research International - March 8, 2024 Category: Environmental Health Authors: Laura Lemons Moreira Ronan Adler Tavella Alicia da Silva Bonif ácio Rodrigo de Lima Brum Livia da Silva Freitas Niely Gale ão da Rosa Moraes Maria Laura Fiasconaro Paula Florencio Ramires Julia Oliveira Penteado Paulo Roberto Martins Baisch Flavio Manoe Source Type: research

Development of Simplified Recombinase Polymerase Amplification Assay for Rapid and Robust Detection of Citrus Yellow Vein Clearing Virus
Curr Microbiol. 2024 Feb 22;81(4):103. doi: 10.1007/s00284-024-03614-y.ABSTRACTCitrus is an economically important fruit crop, belongs to family Rutaceae, cultivated commercially in over 130 countries, which holds a leading profitable position in the international market. The most important citrus varieties are mandarins, oranges, lemons, sweet limes, grapefruits and pomelos. Citrus yellow vein clearing virus (CYVCV) is an important graft transmissible plant pathogen known to reduce productivity of citrus fruits due to its predominant association and widespread occurrence. Requirement of fast, reliable, efficient & eco...
Source: Current Microbiology - February 22, 2024 Category: Microbiology Authors: Nitika Gupta Rakesh Kumar Gopi Kishan Susheel Kumar Sharma Nishant Srivastava Ashwini Kumar Virendra Kumar Baranwal Source Type: research

Defining the role of Th2-associated cytokines in Aspergillus versicolor-induced pulmonary immune responses
Aspergillus versicolor is a fungal contaminant commonly found in damp indoor environments. Chronic exposure to A. versicolor is associated with Th2-mediated immune responses that can lead to allergy and other disease. The mechanistic role of Th2-associated cytokines, IL-4, IL-5, and IL-13, during fungal exposure needs further characterization. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Kelly Weaver, Catherine Blackwood, Angela Lemons, Walter McKinney, Brett Green, Donald Beezhold, Michelle Block, Tara Croston Source Type: research

Characterization of microbial components present in bioconcept metalworking fluid that may contribute to the development of severe lung pathology
Workers at a manufacturing facility using bioconcept metalworking fluid (MWF) engineered to selectively grow the biocontrol organism Pseudomonas pseudoalcaligenes developed a severe lung disease described as bronchiolitis, alveolar ductitis, and emphysema (BADE). Analysis of lung biopsies from affected workers indicated the lung microbiome was similar to that observed in used MWF. We hypothesized that this shift in the lung microbiome may contribute to the development of BADE. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Angela Lemons, Michael Sulyok, Marcia Stanton, Tara Croston Source Type: research

Viruses, Vol. 16, Pages 188: Genotype Sequencing and Phylogenetic Analysis Revealed the Origins of Citrus Yellow Vein Clearing Virus California Isolates
omi The Citrus yellow vein clearing virus (CYVCV) causes a viral disease that has been reported in some citrus-growing regions in countries in Eurasia including Pakistan, India, Türkiye, Iran, China, and South Korea. Recently, CYVCV was detected in a localized urban area in a town in the middle of California’s citrus-growing region and marks the first occurrence of the virus in North America. CYVCV has been reported to be spread by aphid and whitefly vectors and is graft and mechanically transmitted. Hence, it is an invasive pathogen that presents a significant threat to the California citrus...
Source: Viruses - January 26, 2024 Category: Virology Authors: Yong-Duo Sun Raymond Yokomi Tags: Article Source Type: research

Anti-microbial efficacy of a scientifically developed and standardized herbal-alcohol sanitizer
Arch Microbiol. 2024 Jan 25;206(2):77. doi: 10.1007/s00203-023-03805-4.ABSTRACTHands are the primary mode of transmission of microbe-based infections, as they harbor normal microbiota and pathogenic microbes. SARS-CoV-2 has endangered lives worldwide, and WHO has recommended good hygiene practices, especially hand hygiene. In addition, other infectious diseases like diphtheria, measles, tuberculosis, HIV, malaria, etc. are spreading in the shadow of the COVID-19 pandemic. The anti-microbial efficiency of two in-house developed herbal-alcohol based hand sanitizers containing Azadirachta indica, Citrus limon, Zingiber offici...
Source: Archives of Microbiology - January 25, 2024 Category: Microbiology Authors: Rajkumar Tulsawani Kalyani Verma Ekta Kohli Purva Sharma Yogesh Singh Meena None Amitabh Sarkaraisamy Ponmariappan Prashant Kumar Rekha Maithani Source Type: research

Making lemonade out of lemons: an approach to combining variable race and ethnicity data from hospitals for quality and safety efforts
Equity is one of the six core healthcare quality domains in ‘Crossing the Quality Chasm’, published by the Institute of Medicine in 2001.1 While substantial quality measurement and improvement work has focused on improving safety, patient-centredness, timeliness, efficiency and efficacy (the other five domains), far less has focused on health equity measurement and improvement. This is in part due to limited adoption of standardised definitions of racial and ethnicities and therefore limited availability of high-quality data on race and ethnicity.2 Having accurate data is a key first step in addressing health i...
Source: Quality and Safety in Health Care - January 19, 2024 Category: Health Management Authors: Karvonen, K. L., Bardach, N. S. Tags: Editorials Source Type: research