Comparative Analysis of Super-Mini Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for the Management of Renal Calculi ≤2 cm Among Somali Population
Journal of Endourology, Ahead of Print. (Source: Journal of Endourology)
Source: Journal of Endourology - March 27, 2024 Category: Urology & Nephrology Authors: Abdihamid Hassan Hilowle Abdikarim Hussein Mohamed Source Type: research

Treatment of ureteropelvic junction obstruction in patients with renal calculi via laparoscopic pyeloplasty and flexible vacuum-assisted ureteral access sheath ureteroscopy: a multicenter retrospective observational study
Ureteropelvic junction obstruction (UPJO) is a common obstructive disease of the urinary tract. UPJO patients commonly exhibit coexistent renal calculi. The main aim of therapy is to relieve the obstruction an... (Source: BMC Urology)
Source: BMC Urology - March 26, 2024 Category: Urology & Nephrology Authors: Yang Mi, Zhiqin Kang, Jingyu Wang, Liang Yan and Jun Zhang Tags: Research Source Type: research

VAMP1-Related Congenital Myasthenic Syndrome: A Case Report and Literature Review
Neuropediatrics DOI: 10.1055/s-0044-1782675Congenital myasthenic syndrome-25 (CMS-25) is an autosomal recessive neuromuscular disorder caused by a homozygous mutation in VAMP1 gene. To date, only eight types of allelic variants in VAMP1 gene have been reported in 12 cases of CMS-25. Here, we report on an 8-year-old boy with motor developmental delay, axial hypotonia, myopathic face, muscle weakness, strabismus, ptosis, pectus carinatum, kyphoscoliosis, joint contractures, joint laxity, seizures, and recurrent nephrolithiasis. He also had feeding difficulties and recurrent aspiration pneumonia. Brain magnetic resonance imag...
Source: Neuropediatrics - March 26, 2024 Category: Neurology Authors: Y ıldırım, Miraç Yarenci, G ülçin Bilicen Gen ç, Mustafa Berk U çar, Çiğdem İlter Bayav, Secahattin Tekin, Merve Nur Bekta ş, Ömer Teber, Serap Tags: Short Communication Source Type: research

Urine cadmium and urolithiasis: A systematic review and meta-analysis
Environ Res. 2024 Mar 23:118745. doi: 10.1016/j.envres.2024.118745. Online ahead of print.ABSTRACTExposure to cadmium may increase risk of urolithiasis, but the results remain inconclusive. This systematic review and meta-analysis aimed to access the association between cadmium exposure and urolithiasis. We searched Medline/PubMed, Embase, Web of Science Core Collection, and Cochrane Central for studies. The primary outcome was the incidence of urolithiasis compared to reference groups. We used relative risk as the summary effect measure. This meta-analysis included eight observational studies and divided into 39 study pop...
Source: Environmental Research - March 25, 2024 Category: Environmental Health Authors: Yuan-Hsin Chen Chih-Fu Wei Ya-Yun Cheng Carol Mita Chinh Lu Duc Hoang Cheng-Kuan Lin Yu-Tzu Chang David C Christiani Source Type: research

International Alliance of Urolithiasis (IAU) guideline on staghorn calculi management
ConclusionA series of recommendations regarding the management of staghorn calculi, along with related commentary and supporting documentation offered in the present guideline is intended to provide a clinical framework for the practicing urologists in the management of staghorn calculi. (Source: World Journal of Urology)
Source: World Journal of Urology - March 25, 2024 Category: Urology & Nephrology Source Type: research

Simultaneous determination of plasma protein binding of five C-glycosylflavones from TFDS by rapid equilibrium dialysis
In this study, the plasma protein binding of these compounds was determined for the first time in rat and human plasma by rapid equilibrium dialysis combined with HPLC-MS/MS method. The developed method was validated in terms of specificity, linearity, accuracy, precision, extraction effect, matrix effect, and stability. Schaftoside, vicenin-1, vicenin-2, and vicenin-3 exhibited moderate plasma protein binding, ranging from 56.6% to 61.5% in rat plasma and 55.0%-62.9% in human plasma. In comparison, isovitexin demonstrated a higher plasma protein binding in the range of 92.3-93.1% and 95.1-96.2% in rat and human plasma, re...
Source: Analytical Biochemistry - March 24, 2024 Category: Biochemistry Authors: Nan Ding Chen Chao Yishu Liu Peiyong Zheng Xue Li Ming Yang Source Type: research

Simultaneous determination of plasma protein binding of five C-glycosylflavones from TFDS by rapid equilibrium dialysis
In this study, the plasma protein binding of these compounds was determined for the first time in rat and human plasma by rapid equilibrium dialysis combined with HPLC-MS/MS method. The developed method was validated in terms of specificity, linearity, accuracy, precision, extraction effect, matrix effect, and stability. Schaftoside, vicenin-1, vicenin-2, and vicenin-3 exhibited moderate plasma protein binding, ranging from 56.6% to 61.5% in rat plasma and 55.0%-62.9% in human plasma. In comparison, isovitexin demonstrated a higher plasma protein binding in the range of 92.3-93.1% and 95.1-96.2% in rat and human plasma, re...
Source: Analytical Biochemistry - March 24, 2024 Category: Biochemistry Authors: Nan Ding Chen Chao Yishu Liu Peiyong Zheng Xue Li Ming Yang Source Type: research

Laparoscopic pyeloplasty in the treatment of bilateral renal hydronephrosis with bilateral renal stones in a 6-week-old infant
Asian J Surg. 2024 Mar 22:S1015-9584(24)00567-0. doi: 10.1016/j.asjsur.2024.03.137. Online ahead of print.NO ABSTRACTPMID:38521756 | DOI:10.1016/j.asjsur.2024.03.137 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 23, 2024 Category: Surgery Authors: Changkun Mao Chengpin Tao Chao Yang Yongsheng Cao Source Type: research

Kidney manifestations of sarcoidosis
J Autoimmun. 2024 Mar 22:103207. doi: 10.1016/j.jaut.2024.103207. Online ahead of print.ABSTRACTRenal involvement is a clinically relevant organ manifestation of sarcoidosis, leading to increased morbidity and complications. Although the exact incidence remains unknown, renal disease is likely to occur in up to one third of all sarcoidosis patients. Every patient with newly diagnosed sarcoidosis should receive a renal work-up and screening for disrupted calcium metabolism. Amid various forms of glomerulonephritis, granulomatous interstitial nephritis is the most common one, but it rarely leads to renal impairment. Histolog...
Source: Journal of Autoimmunity - March 23, 2024 Category: Allergy & Immunology Authors: Francesco Bonella Adriane Dm Vorselaars Benjamin Wilde Source Type: research

Laparoscopic pyeloplasty in the treatment of bilateral renal hydronephrosis with bilateral renal stones in a 6-week-old infant
Asian J Surg. 2024 Mar 22:S1015-9584(24)00567-0. doi: 10.1016/j.asjsur.2024.03.137. Online ahead of print.NO ABSTRACTPMID:38521756 | DOI:10.1016/j.asjsur.2024.03.137 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 23, 2024 Category: Surgery Authors: Changkun Mao Chengpin Tao Chao Yang Yongsheng Cao Source Type: research

Kidney manifestations of sarcoidosis
J Autoimmun. 2024 Mar 22:103207. doi: 10.1016/j.jaut.2024.103207. Online ahead of print.ABSTRACTRenal involvement is a clinically relevant organ manifestation of sarcoidosis, leading to increased morbidity and complications. Although the exact incidence remains unknown, renal disease is likely to occur in up to one third of all sarcoidosis patients. Every patient with newly diagnosed sarcoidosis should receive a renal work-up and screening for disrupted calcium metabolism. Amid various forms of glomerulonephritis, granulomatous interstitial nephritis is the most common one, but it rarely leads to renal impairment. Histolog...
Source: Journal of Autoimmunity - March 23, 2024 Category: Allergy & Immunology Authors: Francesco Bonella Adriane Dm Vorselaars Benjamin Wilde Source Type: research

Deficient butyrate metabolism in the gut microbiome: an emerging risk factor for recurrent kidney stone disease
(Source: Urolithiasis)
Source: Urolithiasis - March 23, 2024 Category: Urology & Nephrology Source Type: research

Optimal duration of medical expulsive therapy for lower ureteral stones: a critical evaluation
AbstractTo evaluate the optimal duration of Medical Expulsive Therapy (MET) application for distal ureteric stones on a time period based manner. 89 patients with 5 –10 mm distal ureter stones received tamsulosin (0.4 mg) for MET and diclofenac sodium (75 mg) for analgesia. Patients were evaluated once a week for 4 weeks. Radiologic stone passage was evaluated by kidney ureter bladder (KUB) and ultasonography where non-contrast computed tomography (NCCT) w as also performed if needed. While 23 cases (28.4%) were SF after first week, 23 were SF (28.4%) after 2 weeks, 9 cases (11.1%) after 3 and lastly 7 cases (8.6%) be...
Source: Urolithiasis - March 23, 2024 Category: Urology & Nephrology Source Type: research

Getting hot in here! Comparison of Holmium vs. thulium laser in an anatomic hydrogel kidney model
AbstractAs laser technology has advanced, high-power lasers have become increasingly common. The Holmium: yttrium –aluminum-garnet (Ho:YAG) laser has long been accepted as the standard for laser lithotripsy. The thulium fiber laser (TFL) has recently been established as a viable option. The aim of this study is to evaluate thermal dose and temperature for the Ho:YAG laser to the TFL at four different laser se ttings while varying energy, frequency, operator duty cycle (ODC). Utilizing high-fidelity, 3D-printed hydrogel models of a pelvicalyceal collecting system (PCS) with a synthetic BegoStone implanted in the renal pel...
Source: Urolithiasis - March 23, 2024 Category: Urology & Nephrology Source Type: research

N-acetylcysteine regulates oxalate induced injury of renal tubular epithelial cells through CDKN2B/TGF- β/SMAD axis
In conclusion, we found that NAC could play an anti-calculus role by mediating CDKN2B/TGF-β/SMAD axis. (Source: Urolithiasis)
Source: Urolithiasis - March 23, 2024 Category: Urology & Nephrology Source Type: research