The Association of Urolithiasis with Uricosuria, Uricemia and their Combination
CONCLUSIONS: There were no significant differences in hyperuricemia or hyperuricosuria between the two groups of patients or in hyperuricemia among participants without hyperuricosuria.PMID:38420637 (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - February 29, 2024 Category: General Medicine Authors: Amnon Gil Daniel Kushnir Victor Frajewicki Source Type: research

Incident comorbidities in patients with chronic hypoparathyroidism after thyroidectomy: a multicenter nationwide study
ConclusionThis study demonstrates that, in the clinical practice of Spanish endocrinologists, a significant increase in the risk of chronic kidney disease, nephrolithiasis and cardiovascular disease, as well as a reduction in the risk of fractures is detected. These results are of interest for the development of new clinical guidelines and monitoring protocols for patients with hypoparathyroidism. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - February 28, 2024 Category: Endocrinology Source Type: research

Deficient butyrate metabolism in the intestinal microbiome is a potential risk factor for recurrent kidney stone disease
AbstractIntestinal microbiome dysbiosis is a known risk factor for recurrent kidney stone disease (KSD) with prior data suggesting a role for dysfunctional metabolic pathways other than those directly utilizing oxalate. To identify alternative mechanisms, the current study analyzed differences in the metabolic potential of intestinal microbiomes of patients (nā€‰=ā€‰17) and live-in controls (nā€‰=ā€‰17) and determined their relevance to increased risk for KSD using shotgun metagenomic sequencing. We found no differences in the abundance of genes associated with known oxalate degradation pathways, supporting the notion that...
Source: Urolithiasis - February 28, 2024 Category: Urology & Nephrology Source Type: research