Erratum to: Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice
(Source: Skeletal Muscle)
Source: Skeletal Muscle - February 15, 2017 Category: Research Authors: Zoe White, Jessica Terrill, Robert B. White, Christopher McMahon, Phillip Sheard, Miranda D. Grounds and Tea Shavlakadze Source Type: research
Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness
The Ste20-like kinase, SLK, plays an important role in cell proliferation and cytoskeletal remodeling. In fibroblasts, SLK has been shown to respond to FAK/Src signaling and regulate focal adhesion turnover th... (Source: Skeletal Muscle)
Source: Skeletal Muscle - February 2, 2017 Category: Research Authors: Benjamin R. Pryce, Khalid N. Al-Zahrani, S ébastien Dufresne, Natalya Belkina, Cédrik Labrèche, Genaro Patino-Lopez, Jérôme Frenette, Stephen Shaw and Luc A. Sabourin Source Type: research
Inhibition of Stat3 signaling ameliorates atrophy of the soleus muscles in mice lacking the vitamin D receptor
Although skeletal muscle wasting has long been observed as a clinical outcome of impaired vitamin D signaling, precise molecular mechanisms that mediate the loss of muscle mass in the absence of vitamin D sign... (Source: Skeletal Muscle)
Source: Skeletal Muscle - January 25, 2017 Category: Research Authors: Suchitra D. Gopinath Source Type: research
A novel method for the quantification of fatty infiltration in skeletal muscle
Fatty infiltration of the skeletal muscle is a common but poorly understood feature of many myopathies. It is best described in human muscle, where non-invasive imaging techniques and representative histology ... (Source: Skeletal Muscle)
Source: Skeletal Muscle - January 10, 2017 Category: Research Authors: Nicole K. Biltz and Gretchen A. Meyer Source Type: research
Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice
This study investigates the molecular basis underlying t... (Source: Skeletal Muscle)
Source: Skeletal Muscle - December 13, 2016 Category: Research Authors: Zoe White, Jessica Terrill, Robert B. White, Christopher McMahon, Phillip Sheard, Miranda D. Grounds and Tea Shavlakadze Source Type: research
Laminin 521 maintains differentiation potential of mouse and human satellite cell-derived myoblasts during long-term culture expansion
Large-scale expansion of myogenic progenitors is necessary to support the development of high-throughput cellular assays in vitro and to advance genetic engineering approaches necessary to develop cellular the... (Source: Skeletal Muscle)
Source: Skeletal Muscle - December 13, 2016 Category: Research Authors: Christopher M. Penton, Vasudeo Badarinarayana, Joy Prisco, Elaine Powers, Mark Pincus, Ronald E. Allen and Paul R. August Source Type: research
Skeletal muscle characteristics are preserved in hTERT/cdk4 human myogenic cell lines
hTERT/cdk4 immortalized myogenic human cell lines represent an important tool for skeletal muscle research, being used as therapeutically pertinent models of various neuromuscular disorders and in numerous fun... (Source: Skeletal Muscle)
Source: Skeletal Muscle - December 8, 2016 Category: Research Authors: Matthew Thorley, St éphanie Duguez, Emilia Maria Cristina Mazza, Sara Valsoni, Anne Bigot, Kamel Mamchaoui, Brennan Harmon, Thomas Voit, Vincent Mouly and William Duddy Source Type: research
CCAAT/enhancer binding protein β is required for satellite cell self-renewal
Postnatal growth and repair of skeletal muscle relies upon a population of quiescent muscle precursor cells, called satellite cells that can be activated to proliferate and differentiate into new myofibers, as... (Source: Skeletal Muscle)
Source: Skeletal Muscle - December 7, 2016 Category: Research Authors: Neena Lala-Tabbert, Hamood AlSudais, Fran çois Marchildon, Dechen Fu and Nadine Wiper-Bergeron Source Type: research
Muscle PGC-1 α modulates satellite cell number and proliferation by remodeling the stem cell niche
The myogenic capacity of satellite cells (SCs), adult muscle stem cells, is influenced by aging, exercise, and other factors. In skeletal muscle, the peroxisome proliferator-activated receptor γ coactivator 1α... (Source: Skeletal Muscle)
Source: Skeletal Muscle - December 2, 2016 Category: Research Authors: Ivana Dinulovic, Regula Furrer, Markus Beer, Arnaud Ferry, Bettina Cardel and Christoph Handschin Source Type: research
Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4
Nuclear bodies, such as nucleoli, PML bodies, and SC35 speckles, are dynamic sub-nuclear structures that regulate multiple genetic and epigenetic processes. Additional regulation is provided by RNA/DNA handlin... (Source: Skeletal Muscle)
Source: Skeletal Muscle - December 1, 2016 Category: Research Authors: Sachiko Homma, Mary Lou Beermann, Bryant Yu, Frederick M. Boyce and Jeffrey Boone Miller Source Type: research
Heme oxygenase and carbon monoxide protect from muscle dystrophy
Duchenne muscle dystrophy (DMD) is one of the most common lethal genetic diseases of children worldwide and is 100% fatal. Steroids, the only therapy currently available, are marred by poor efficacy and a high... (Source: Skeletal Muscle)
Source: Skeletal Muscle - November 28, 2016 Category: Research Authors: Mun Chun Chan, Olivia Ziegler, Laura Liu, Glenn C. Rowe, Saumya Das, Leo E. Otterbein and Zoltan Arany Source Type: research
