Correction to: Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells
After publication of this article [1], the authors noted that the legends for supplementary files Figures S3 and S4 were truncated in the production process, therefore lacking some information concerning these... (Source: Skeletal Muscle)
Source: Skeletal Muscle - June 6, 2018 Category: Research Authors: Natalia Pietrosemoli, S ébastien Mella, Siham Yennek, Meryem B. Baghdadi, Hiroshi Sakai, Ramkumar Sambasivan, Francesca Pala, Daniela Di Girolamo and Shahragim Tajbakhsh Tags: Correction Source Type: research
Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats
A low-protein diet supplemented with ketoacids (LPD + KA) maintains the nutritional status of patients with chronic kidney disease (CKD). Oxidative damage and mitochondrial dysfunction associated with the upre... (Source: Skeletal Muscle)
Source: Skeletal Muscle - May 31, 2018 Category: Research Authors: Dongtao Wang, Lianbo Wei, Yajun Yang and Huan Liu Tags: Research Source Type: research
TRAPPC11 and GOSR2 mutations associate with hypoglycosylation of α-dystroglycan and muscular dystrophy
Transport protein particle (TRAPP) is a supramolecular protein complex that functions in localizing proteins to the Golgi compartment. The TRAPPC11 subunit has been implicated in muscle disease by virtue of ho... (Source: Skeletal Muscle)
Source: Skeletal Muscle - May 31, 2018 Category: Research Authors: Austin A. Larson, Peter R. Baker II, Miroslav P. Milev, Craig A. Press, Ronald J. Sokol, Mary O. Cox, Jacqueline K. Lekostaj, Aaron A. Stence, Aaron D. Bossler, Jennifer M. Mueller, Keshika Prematilake, Thierry Fotsing Tadjo, Charles A. Williams, Michael Tags: Case report Source Type: research
A novel canine model for Duchenne muscular dystrophy (DMD): single nucleotide deletion in DMD gene exon 20
Boys with Duchenne muscular dystrophy (DMD) have DMD gene mutations, with associated loss of the dystrophin protein and progressive muscle degeneration and weakness. Corticosteroids and palliative support are cur... (Source: Skeletal Muscle)
Source: Skeletal Muscle - May 29, 2018 Category: Research Authors: Sara Mata L ópez, James J. Hammond, Madison B. Rigsby, Cynthia J. Balog-Alvarez, Joe N. Kornegay and Peter P. Nghiem Tags: Case report Source Type: research
miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context
Duchenne (DMD) and Becker (BMD) muscular dystrophies are caused by mutations in the DMD gene coding for dystrophin, a protein being part of a large sarcolemmal protein scaffold that includes the neuronal nitric o... (Source: Skeletal Muscle)
Source: Skeletal Muscle - April 27, 2018 Category: Research Authors: Marine Guilbaud, Christel Gentil, C écile Peccate, Elena Gargaun, Isabelle Holtzmann, Carole Gruszczynski, Sestina Falcone, Kamel Mamchaoui, Rabah Ben Yaou, France Leturcq, Laurence Jeanson-Leh and France Piétri-Rouxel Tags: Research Source Type: research
Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function
The ability to assess skeletal muscle function and delineate regulatory mechanisms is essential to uncovering therapeutic approaches that preserve functional independence in a disease state. Skeletal muscle pr... (Source: Skeletal Muscle)
Source: Skeletal Muscle - April 17, 2018 Category: Research Authors: Michael D. Tarpey, Adam J. Amorese, Nicholas P. Balestrieri, Terence E. Ryan, Cameron A. Schmidt, Joseph M. McClung and Espen E. Spangenburg Tags: Research Source Type: research
Skeletal, cardiac, and respiratory muscle function and histopathology in the P448Lneo − mouse model of FKRP-deficient muscular dystrophy
Fukutin-related protein (FKRP) mutations are the most common cause of dystroglycanopathies known to cause both limb girdle and congenital muscular dystrophy. The P448Lneo − mouse model has a knock-in mutation in t... (Source: Skeletal Muscle)
Source: Skeletal Muscle - April 6, 2018 Category: Research Authors: Qing Yu, Melissa Morales, Ning Li, Alexander G. Fritz, Ren Ruobing, Anthony Blaeser, Ershia Francois, Qi-Long Lu, Kanneboyina Nagaraju and Christopher F. Spurney Tags: Research Source Type: research
An RNAi based screen in Drosophila larvae identifies fascin as a regulator of myoblast fusion and myotendinous junction structure
A strength of Drosophila as a model system is its utility as a tool to screen for novel regulators of various functional and developmental processes. However, the utility of Drosophila as a screening tool is depe... (Source: Skeletal Muscle)
Source: Skeletal Muscle - April 6, 2018 Category: Research Authors: Jaclyn M. Camuglia, Torrey R. Mandigo, Richard Moschella, Jenna Mark, Christine H. Hudson, Derek Sheen and Eric S. Folker Tags: Research Source Type: research
The complexity of titin splicing pattern in human adult skeletal muscles
Mutations in the titin gene (TTN) cause a large spectrum of diseases affecting skeletal and/or cardiac muscle. TTN includes 363 coding exons, a repeated region with a high degree of complexity, isoform-specific e... (Source: Skeletal Muscle)
Source: Skeletal Muscle - March 29, 2018 Category: Research Authors: Marco Savarese, Per Harald Jonson, Sanna Huovinen, Lars Paulin, Petri Auvinen, Bjarne Udd and Peter Hackman Tags: Research Source Type: research
Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle
Parkin is a ubiquitin ligase that is involved in the selective removal of dysfunctional mitochondria. This process is termed mitophagy and can assist in mitochondrial quality control. Endurance training can pr... (Source: Skeletal Muscle)
Source: Skeletal Muscle - March 17, 2018 Category: Research Authors: Chris Chin Wah Chen, Avigail T. Erlich and David A. Hood Tags: Research Source Type: research
A need for NAD+ in muscle development, homeostasis, and aging
Skeletal muscle enables posture, breathing, and locomotion. Skeletal muscle also impacts systemic processes such as metabolism, thermoregulation, and immunity. Skeletal muscle is energetically expensive and is... (Source: Skeletal Muscle)
Source: Skeletal Muscle - March 7, 2018 Category: Research Authors: Michelle F. Goody and Clarissa A. Henry Tags: Review Source Type: research
A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses
The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic hallmark of IMM is lymphocytic infiltration of myofib... (Source: Skeletal Muscle)
Source: Skeletal Muscle - March 6, 2018 Category: Research Authors: Carrie J. Finno, Giuliana Gianino, Sudeep Perumbakkam, Zo ë J. Williams, Matthew H. Bordbari, Keri L. Gardner, Erin Burns, Sichong Peng, Sian A. Durward-Akhurst and Stephanie J. Valberg Tags: Research Source Type: research
Diversification of the muscle proteome through alternative splicing
Skeletal muscles express a highly specialized proteome that allows the metabolism of energy sources to mediate myofiber contraction. This muscle-specific proteome is partially derived through the muscle-specif... (Source: Skeletal Muscle)
Source: Skeletal Muscle - March 6, 2018 Category: Research Authors: Kiran Nakka, Claudia Ghigna, Davide Gabellini and F. Jeffrey Dilworth Tags: Review Source Type: research
HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses
Denervation triggers numerous molecular responses in skeletal muscle, including the activation of catabolic pathways and oxidative stress, leading to progressive muscle atrophy. Histone deacetylase 4 (HDAC4) m... (Source: Skeletal Muscle)
Source: Skeletal Muscle - February 24, 2018 Category: Research Authors: Eva Pigna, Alessandra Renzini, Emanuela Greco, Elena Simonazzi, Stefania Fulle, Rosa Mancinelli, Viviana Moresi and Sergio Adamo Tags: Research Source Type: research
Nilotinib impairs skeletal myogenesis by increasing myoblast proliferation
Tyrosine kinase inhibitors (TKIs) are effective therapies with demonstrated antineoplastic activity. Nilotinib is a second-generation FDA-approved TKI designed to overcome Imatinib resistance and intolerance i... (Source: Skeletal Muscle)
Source: Skeletal Muscle - February 20, 2018 Category: Research Authors: Osvaldo Contreras, Maximiliano Villarreal and Enrique Brandan Tags: Research Source Type: research
