Portopulmonary hypertension: Success with combined medical treatment
We report here the case of a 57-year-old man with portopulmonary hypertension caused by chronic hepatosplenic schistosomiasis and also liver cirrhosis due to hepatitis C and alcoholism. As well as treating both diseases, portopulmonary hypertension was successfully managed with tadalafil and macitentan as maintenance therapy. This case reminds clinicians that pulmonary hypertension can be multifactorial, a good diagnosis and a multidisciplinary treatment can lead to improved prognosis. (Source: Respirology Case Reports)
Source: Respirology Case Reports - March 17, 2023 Category: Respiratory Medicine Authors: Mar ía Hernández,
Violeta Esteban,
Paloma Ruiz,
Ignacio Boira,
Phillip Wickmann,
José N. Sancho‐Chust,
Joan Gil Tags: CASE REPORT Source Type: research
Pulmonary embolism or COVID ‐19 pneumonia? A case report
During the COVID-19 pandemic, a high index of suspicion is required for the timely diagnosis of pulmonary embolism, especially in patients with identifiable risk factors. This is specifically true for patients who cannot express their symptoms due to neurocognitive disorders. AbstractPulmonary embolism (PE) is the most severe clinical presentation of venous thromboembolism (VTE), which can be challenging to diagnose due to its non-specific symptoms. The overlapping clinical symptoms of Coronavirus disease 2019 (COVID-19) and PE may make distinguishing between the two difficult. Thus, the diagnosis of PE may be delayed or m...
Source: Respirology Case Reports - March 16, 2023 Category: Respiratory Medicine Authors: Nahid Borna,
Maryam Niksolat,
Behnam Shariati,
Vahid Saeedi,
Leila Kamalzadeh Tags: CASE REPORT Source Type: research
Using cryobiopsy with Radial EBUS in high ‐bleeding‐risk, peripheral pulmonary lesions (PPL): description of cases and technique
This case series describes four patients with peripheral pulmonary lesions (PPL), undergoing cryobiopsy with radial EBUS for suspected lung cancer, and later diagnosed to have a PPL deemed to be of a high bleeding risk. The use of cryobiopsy with radial ultrasonic examination for the vasculature of the PPL, bronchial blocker use, and airway protection as well as an expert team preserved the safety of the procedure. AbstractCryobiopsy is an emerging tool in the diagnosis of peripheral pulmonary lesions (PPL) and becoming an important tool in the toolbox. Anecdotally the data on cryobiopsy use in the lung was extrapolated fr...
Source: Respirology Case Reports - March 15, 2023 Category: Respiratory Medicine Authors: Samantha Herath Tags: CASE SERIES Source Type: research
Pseudoprogression during induction treatment with nivolumab plus ipilimumab combined with chemotherapy for metastatic lung adenocarcinoma: A case report
We present the case of pseudoprogression after the first cycle of dual immunotherapy with chemotherapy in a 55-year-old male with invasive mucinous adenocarcinoma. AbstractThe incidence rate of pseudoprogression during immune checkpoint inhibitor monotherapy for non-small cell lung cancer is reportedly 3.6% –6.9%, while pseudoprogression during chemoimmunotherapy is rare. Reports on pseudoprogression during dual immunotherapy combined with chemotherapy are lacking. Herein, a 55-year-old male with invasive mucinous adenocarcinoma (cT2aN2M1c [OTH, PUL], stage IVB, and programmed death-ligand 1 expressi on<1%), renal dys...
Source: Respirology Case Reports - March 14, 2023 Category: Respiratory Medicine Authors: Yusuke Kunimatsu,
Yukari Kano,
Rei Tsutsumi,
Izumi Sato,
Mai Tanimura,
Keiko Tanimura,
Takayuki Takeda Tags: CASE REPORT Source Type: research
Anti ‐synthetase syndrome associated interstitial lung disease after combination dual immune checkpoint inhibition
In this study, we describe the first reported case of antisynthetase syndrome; characterized by circulating anti-EJ (glycyl) t-RNA synthetase antibodies accompanied by relapsing, fibrosing and treatment-resistant interstitial pneumonitis. This case study highlights the need to also consider rarer phenotypes of ICI-induced inflammatory lung injury beyond conventional ‘ICI pneumonitis’ in the diagnostic workup of these patients. Differentiating between rare forms of CTD-ILD (in particular IIM-ILD) and conventional ‘ICI pneumonitis’ has important implications for the expected natural history and optimal treatment pa...
Source: Respirology Case Reports - March 13, 2023 Category: Respiratory Medicine Authors: Peter T. Bell,
Thomas Beaton,
Matthew Terrill,
David Gillis,
John Goddard Tags: CASE REPORT Source Type: research
Combining three ‐dimensional fluoroscopy guide system with single‐use bronchoscopes for diagnosis of peripheral lesions: First two cases
We report two cases of PPLs sampling procedures combining the use of aScope 5 single-use bronchoscope and CIOS 3D Spin Mobile fluoroscopy system. The use of ever-new disposable bronchoscopes for sampling peripheral lesions is a viable alternative to reusable bronchoscopes for advanced bronchoscopy procedures. AbstractPulmonary Peripheral Lesions (PPLs) diagnosis is usually performed using a guidance system in combination with bronchoscopes and diagnostic tools. We report two cases of PPLs sampling procedures combining the use of the single-use bronchoscope Ambu aScope 5 Broncho and CIOS 3D Spin Mobile (Siemens Healthineers...
Source: Respirology Case Reports - March 11, 2023 Category: Respiratory Medicine Authors: Filippo Patrucco,
Andrea D'Alessio,
Marco Brambilla,
Piero Emilio Balbo Tags: CASE REPORT Source Type: research
A rare case of melioidosis presenting as pericarditis and pneumonia in a patient with poorly controlled diabetes mellitus
We report a rare case of melioidosis presenting as pericarditis and pneumonia in a 61-year-old male patient with poorly controlled diabetes mellitus. He was initially misdiagnosed withPseudomonas aeruginosa infection and later treated empirically as tuberculosis pericarditis for 2 months, before reaching the diagnosis of melioidosis. (Source: Respirology Case Reports)
Source: Respirology Case Reports - March 9, 2023 Category: Respiratory Medicine Authors: Cheuk Cheung Derek Leung,
Ching Man Ngai,
Chun Kit Wong,
Yu Hong Chan Tags: CASE REPORT Source Type: research
Issue Information
(Source: Respirology Case Reports)
Source: Respirology Case Reports - March 8, 2023 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Eradication of post ‐lobectomy mucormycosis and bacterial empyema with intrapleural antimicrobial therapy in a patient with surgically resected Mycobacterium xenopi (non‐tuberculous Mycobacteria) pulmonary infection
We present a 57-year-old gentleman who developed chronic mucormycosis (Cunninghamella sp.) and bacterial (Enterococcus sp.) empyema in a high-risk post-lobectomy space in the setting of a non-expandable lung following non-tuberculous mycobacterial infection. This was successfully treated with a combination of systemic and intrapleural therapies. AbstractEmpyema thoracis is a collection of pus in the pleural space associated with pleural fibrin deposition. Treatment involves systemic antimicrobials, pleural drainage, intrapleural enzymes and sometimes decortication. Our case is a 57-year-old gentleman who developed chronic ...
Source: Respirology Case Reports - March 8, 2023 Category: Respiratory Medicine Authors: Charlotte Wigston,
Emily Woolnough,
Ohide Otome,
Lucas Sanders,
Edward Fysh Tags: CASE REPORT Source Type: research
Immune checkpoint inhibitor ‐related haemophagocytic lymphohistiocytosis in a patient with non‐small cell lung carcinoma
We present a case, in whom pancytopenia with fever and hyperferritinaemia led us to suspect HLH. Early diagnosis of ICI-related HLH is essential for a better outcome. Key messageHemophagocytic lymphohistiocytosis (HLH) has been reported as a rare complication of immune checkpoint inhibitors (ICI); however, ICI-related HLH is a life-threatening and comparatively late adverse event. Early diagnosis is critical, and it should be included in the differential diagnosis especially in patients with cytopenia with fever and hyperferritinaemia. (Source: Respirology Case Reports)
Source: Respirology Case Reports - March 8, 2023 Category: Respiratory Medicine Authors: Setsuko Oyama,
Tatsuya Shirai,
Yukiko Abe,
Maya Tsuchiya,
Toshiya Inui,
Kozo Suhara,
Satoshi Noto,
Mitsuhiro Kamimura Tags: CLINICAL IMAGE Source Type: research
Pleural fluid milkshakes: three cases with different aetiologies
Contrary to popular belief, the classical milky appearance of pleural fluid is seen in less than half of patients with chylothorax. In this case series, we present three patients with biochemically proven chylothorax: each with a different presentation, pleural fluid appearance, underlying cause, management strategy, and clinical outcome. Lymphoma, tuberculosis, and presumed amyloidosis are underlying causes in our patients. AbstractIn clinical practice, chylothorax is usually suspected in any patient with milky pleural fluid. However, contrary to popular belief, milky appearance of pleural fluid is seen in less than half ...
Source: Respirology Case Reports - March 8, 2023 Category: Respiratory Medicine Authors: Nai ‐Chien Huan,
Hooi Ann Tan,
Hema Yamini Ramarmuty,
Subramaniam Ponnuvelu,
Shivaanand Letcheminan,
Kunji Kannan Sivaraman Kannan Tags: CASE SERIES Source Type: research
A case of Rasmussen's aneurysm caused by pulmonary nontuberculous mycobacterium
We report a Rasmussen's aneurysm due to NTM. Key messageRasmussen's aneurysm was originally described as a rare cause of hemoptysis in tuberculosis. Dilatation of the pulmonary artery wall is caused by tuberculosis inflammation. Recently, the incidence of non-tuberculous mycobacterial (NTM) disease has increased; it now exceeds that of tuberculosis. We report a Rasmussen's aneurysm due to NTM. (Source: Respirology Case Reports)
Source: Respirology Case Reports - February 24, 2023 Category: Respiratory Medicine Authors: Maya Plantilla,
Shohei Nozu,
Norihiko Nakanishi,
Yoshihiro Ishimaru Tags: CLINICAL IMAGE Source Type: research
Subcutaneous and muscle layer seroma complicated with thoracentesis
Diagnostic thoracentesis is a basic and relatively safe diagnostic method for patients with pleural effusion. However, complications of thoracentesis are rare and not well known because of the low incidence. Herein, we report a case of subcutaneous and muscle layer seroma following thoracentesis. Key messageDiagnostic thoracentesis is a basic and relatively safe diagnostic method for patients with pleural effusion. However, complications of thoracentesis are rare and not well known because of the low incidence. Herein, we report a case of subcutaneous and muscle layer seroma following thoracentesis. (Source: Respirology Case Reports)
Source: Respirology Case Reports - February 23, 2023 Category: Respiratory Medicine Authors: Yasuhito Sekimoto,
Makiko Kohmaru,
Tomoko Okuma,
Manabu Tajima,
Mitsuaki Sekiya Tags: CLINICAL IMAGE Source Type: research
Survival after lipiodol escape at embolization for lung transplant chylothorax
We present imaging of lipiodil escape after thoracic duct embolization for transplant associated chylothorax leading to transient impairment, then resolution in a 67-year-old woman. Key messageWe present imaging of lipiodil escape after thoracic duct embolization for transplant associated chylothorax leading to transient impairment, then resolution. (Source: Respirology Case Reports)
Source: Respirology Case Reports - February 23, 2023 Category: Respiratory Medicine Authors: Hugh Buzacott,
Jaideep Vazirani,
Gregory Ian Snell Tags: CLINICAL IMAGE Source Type: research
Resection of a colloid adenocarcinoma of the lung: A case report
In this report, we describe a case of colloid adenocarcinoma of the lung with a 5-year recurrence-free follow-up. The patient is a 66-year-old woman. During postoperative follow-up for ovarian cancer, chest CT showed a 45 × 30 mm sized mass in the left lung with mixed low-absorption areas inside that were suspicious of cystic lesion. We suspected metastatic lung tumour, and performed lower lobectomy. Pathological examination revealed pale tumour cells forming a glandular lumen with internal mucus production. Based on the results of immunostaining we diagnosed colloid adenocarcinoma of the lung. She received postope...
Source: Respirology Case Reports - February 22, 2023 Category: Respiratory Medicine Authors: Yuya Kogita,
Naoko Ose,
Kotaro Kawagishi,
Eiichi Morii,
Yasushi Shintani Tags: CASE REPORT Source Type: research
