A hole lot of trouble: Severe bilateral anastomotic dehiscence following bilateral single sequential lung transplant
We describe a case of a 22-year-old female who developed significant bilateral anastomotic dehiscence with severe ischaemia following a bilateral single sequential lung transplant (BSSLTx). Following an intensive antimicrobial regimen, judicious bronchoscopic surveillance, and a prolonged inpatient stay, the dehiscence resolved without requiring further surgical intervention. Our case highlights a space in the literature for further research with regard to airway complications post-lung transplant and their management. (Source: Respirology Case Reports)
Source: Respirology Case Reports - May 24, 2023 Category: Respiratory Medicine Authors: Cameron White,
Alice Stuart,
Marshall Plit,
Monique Malouf,
Paul Lilburn Tags: CASE REPORT Source Type: research
One ‐year clinical experience on the use of Nintedanib in systemic sclerosis
We reviewed eleven patients with Systemic Sclerosis-related ILD who were referred to our Scleroderma Unit from January 2020 to January 2021 and who started Nintedanib. AbstractWe reviewed 11 patients with systemic sclerosis-related ILD who were referred to our Scleroderma Unit from January 2020 to January 2021 and started Nintedanib. Non-specific interstitial pneumonia (NSIP) was prevalent (45%), usual interstitial pneumonia (UIP) and UIP/NSIP pattern were both 27%. Only one patient had a history of smoking. Eight patients were on mycophenolate mofetil (MMF), eight were treated with corticosteroids (mean dose 5 mg/day of...
Source: Respirology Case Reports - May 23, 2023 Category: Respiratory Medicine Authors: Luca Magnani,
Amelia Spinella,
Sofia Testoni,
Federica Lumetti,
Chiara Scelfo,
Lucia Dardani,
Gianluigi Bajocchi,
Enrico Clini,
Carlo Salvarani,
Dilia Giuggioli Tags: CASE SERIES Source Type: research
Pulmonary alveolar proteinosis after lung transplantation: Two case reports and literature review
Pulmonary alveolar proteinosis (PAP) affecting transplanted lungs is not well recognized. Herein, we report two cases of PAP after lung transplantation (LTx) and their management. Transplant physicians should be aware of this rare complication to avoid misconducting immunosuppressive management. AbstractPulmonary alveolar proteinosis (PAP) affecting transplanted lungs is not well recognized. Herein, we report two cases of PAP after lung transplantation (LTx). The first case was a 4-year-old boy with hereditary pulmonary fibrosis who underwent bilateral LTx and presented with respiratory distress on postoperative day (POD) ...
Source: Respirology Case Reports - May 23, 2023 Category: Respiratory Medicine Authors: Shinichi Kawana,
Kentaroh Miyoshi,
Shin Tanaka,
Seiichiro Sugimoto,
Dai Shimizu,
Kei Matsubara,
Mikio Okazaki,
Noboru Hattori,
Shinichi Toyooka Tags: CASE REPORT Source Type: research
Management of alveolar ‐pleural fistula secondary to invasive pulmonary aspergillosis with bronchial occlusion using a combination of Endobronchial Watanabe Spigot and N‐butyl‐2‐cyanoacrylate: A case report
We report a case of alveolar-pleural fistula managed by bronchial occlusion using a combination of Endobronchial Watanabe Spigot and N-butyl-2-cyanoacrylate. AbstractAlveolar-pleural fistulas that do not improve with thoracic drainage can be conservatively treated via endobronchial occlusion and pleurodesis, among other options. However, for inoperable cases, the treatment strategy to be followed, in the event that conventional conservative management fails, is unclear. Herein, we report a case of alveolar-pleural fistula managed by bronchial occlusion using a combination of Endobronchial Watanabe Spigot (EWS) and N-butyl-...
Source: Respirology Case Reports - May 17, 2023 Category: Respiratory Medicine Authors: Shinya Tsukamoto,
Kazuma Nagata,
Keisuke Tomii Tags: CASE REPORT Source Type: research
A 92 ‐year‐old patient with thoracic empyema successfully treated by CT‐guided insertion of a pigtail catheter
We present a case report of a 92-year-old patient with thoracic empyema, who was successfully treated via CT-guided insertion of a pigtail catheter. We believe that this educational case serves as a testament to the fact that even the most aged patients can be successfully treated with resourcefulness. AbstractWe present a case report of a 92-year-old patient with thoracic empyema, who was successfully treated via CT-guided insertion of a pigtail catheter. The advanced age of the patient often poses challenges in managing pyothorax due to limited physical activity and cognitive decline stemming from decreased activities of...
Source: Respirology Case Reports - May 16, 2023 Category: Respiratory Medicine Authors: Kohei Fujita,
Masataka Hirai,
Zentaro Saito,
Takanori Ito,
Takuma Imakita,
Issei Oi,
Osamu Kanai,
Hiromasa Tachibana,
Tadashi Mio Tags: CASE REPORT Source Type: research
Ultrasound ‐controlled transthoracic true‐cut needle biopsy in pulmonary nodular amyloidosis
The current case report presents a 59-year-old man with imaging studies of the thorax showing nodular lesions in the lungs bilaterally. Preliminary diagnoses for possible granulomatosis (tuberculosis) or pulmonary metastatic dissemination of a neoplastic process were made. An ultrasound-controlled transthoracic true-cut needle biopsy of a subpleural lesion was performed, confirming the diagnosis of ‘pulmonary nodular amyloidosis’. AbstractThe current case report presents a 59-year-old man with imaging studies of the thorax showing nodular lesions in the lungs bilaterally. Based on radiographic and CT images, preliminar...
Source: Respirology Case Reports - May 16, 2023 Category: Respiratory Medicine Authors: Teodora Z. Mihalova,
Silviya S. Ivanova,
Evgeni V. Mekov,
Yordanka Т. Yamakova,
Rosen E. Petkov Tags: CASE REPORT Source Type: research
Furious lung abscess due to Parvimonas micra
We present a case of lung abscess due toParvimonas micra in a 57 year old woman who did not respond to antibiotics and needed surgical resection, indicating the high virulence of this bacteria. Key messageParvimonas micra commonly present in the oral cavity and intestinal tract of humans.P. micra indicating a high virulence, has the potential of forming abscess. The infection ofP. micra may require surgical excision. (Source: Respirology Case Reports)
Source: Respirology Case Reports - May 16, 2023 Category: Respiratory Medicine Authors: Shinnosuke Fukushima,
Hideharu Hagiya,
Hiromichi Naito,
Fumio Otsuka Tags: CLINICAL IMAGE Source Type: research
Severe asthma remaining well ‐controlled after mepolizumab discontinuation: A case report and literature review
Mepolizumab, a humanized anti-IL-5 monoclonal antibody used for severe asthma, results in reduced asthma exacerbations, improved lung function, reduced oral corticosteroid use, and improved quality of life. But little is known about the effects of withdrawal after long-term treatment. Here, we report a case of a patient with asthma, well-controlled without exacerbation after withdrawal of mepolizumab. AbstractMepolizumab, a humanized anti-IL-5 monoclonal antibody used for severe asthma, results in a reduced rate of asthma exacerbation, improved lung function, reduced oral corticosteroid use, and improved quality of life. A...
Source: Respirology Case Reports - May 12, 2023 Category: Respiratory Medicine Authors: Takahiro Matsuyama,
Yuya Tomioka,
Hiromi Matsuyama,
Yusuke Kamenohara,
Kengo Tanigawa,
Yoichi Dotake,
Yoko Hagihara,
Koichi Takagi,
Kentaro Machida,
Hiromasa Inoue Tags: CASE REPORT Source Type: research
Massive pulmonary embolism led to cardiac arrest two days after thoracoscopy in a young male with pleural tuberculosis
We describe a fatal case of a 30-year-old previously healthy male with pleural tuberculosis who developed a massive pulmonary embolism with subsequent cardiac arrest after a diagnostic medical thoracoscopy. Computed tomography pulmonary angiogram showed major right pulmonary embolism. Unfortunately, the patient passed away despite resuscitation and extensive organ support in the intensive care unit. This case highlights the thrombotic risk in this population group in order to avoid such devastating complications. AbstractTB itself is considered an independent risk factor for VTE; however, developing pulmonary embolism afte...
Source: Respirology Case Reports - May 9, 2023 Category: Respiratory Medicine Authors: Wael Kanjo,
Shahem Abbarh,
Amina Bougaila,
Nagham Sadik,
Mhd Baraa Habib Tags: CASE REPORT Source Type: research
Intrapleural therapy for pleural infection from bronchopleural fistula in an adult with hyper ‐IgE syndrome
We presented the case of an adult patient with hyper-IgE syndrome (HIES) who was admitted acutely with a large hydropneumothorax from lung consolidation, a bronchopleural fistula and pleural infection. He has had recurrent pulmonary and skin infections since childhood and longstanding pneumatoceles. He was treated with systemic antibiotics and chest tube drainage. Administration of two doses of low-dose intrapleural therapy (1 mg tissue plasminogen activator and 5 mg deoxyribonuclease) allowed complete evacuation of his residual loculated pleural fluid, aided resolution of his infection without provoking a significant...
Source: Respirology Case Reports - May 6, 2023 Category: Respiratory Medicine Authors: Sam Faber,
Andrew McLean ‐Tooke,
Yi Jin Kuok,
Y. C. Gary Lee Tags: CASE REPORT Source Type: research
PD ‐L1‐negative non‐small cell lung cancer harbouring a rare BRAF mutation with successful treatment of first‐line pembrolizumab plus chemotherapy: A case report and review the literature
We document the case of a 63-year-old patient with NSCLC harbouring a rareBRAF E501Q mutation, who had a prolonged response to immunotherapy combined with chemotherapy in Vietnam. AbstractBRAF mutations are uncommon in non-small cell lung cancer (NSCLC), accounting for less than 5% of all NSCLC cases. The utilization of targeted therapies in non-V600EBRAF mutant NSCLC is considered controversial, although non-V600E genotype is reported in ~50% of allBRAF mutant patients. We document the case of a 63-year-old patient with NSCLC harbouring a rareBRAF E501Q mutation, who had prolonged response to immunotherapy combined with c...
Source: Respirology Case Reports - May 4, 2023 Category: Respiratory Medicine Authors: Kien Hung Do,
Tai Van Nguyen,
Phuong Nguyen Thi Bich,
Gia Hoang Nguyen,
Chu Van Nguyen Tags: CASE REPORT Source Type: research
Combined treatment with beaded EWS, Gore ‐tex patch and N‐butyl‐2‐cyanoacrylate for bronchial fistula: The novel “sandwich method”
In this report, we describe, for the first time, a novel method for closing bronchopleural fistula (BPF) using an endobronchial Watanabe spigot (EWS), polyglycolic acid (PGA) sheet and N-butyl-2-cyanoacrylate (NBCA). We named this method the “sandwich method.” AbstractAn 84-year-old man underwent right basal segmentectomy for primary lung cancer and developed empyema accompanied by a bronchopleural fistula (BPF). Emergency open-window thoracotomy was performed. Although the general and nutritional conditions improved, the fistula did not close naturally, and we planned to close it 6 months after surgery. In this rep...
Source: Respirology Case Reports - May 4, 2023 Category: Respiratory Medicine Authors: Marino Yamamoto,
Masaya Tamura,
Ryohei Miyazaki,
Hironobu Okada Tags: CASE REPORT Source Type: research
Azygos vein thrombosis despite rivaroxaban therapy in a patient with breast cancer: A rare entity
Azygos vein thrombosis (AVT) is an extremely rare type of venous thromboembolism. It is commonly associated with predisposing factors such as azygous vein aneurysm and malignancy including cholangiocarcinoma and renal cell carcinoma. Here we report a rare case of AVT associated with metastatic breast cancer. Key messageIn the light of this case, azygos and hemiazygos veins should be evaluated carefully in thorax CT scans. This rare case is also important in terms of the occurrence of AVT in a patient receiving rivaroxaban therapy. The outcomes and recurrence rates of these patients should also be reported for the decision ...
Source: Respirology Case Reports - April 29, 2023 Category: Respiratory Medicine Authors: Guliz Degirmenci,
Celal Satici Tags: CLINICAL IMAGE Source Type: research
Issue Information
(Source: Respirology Case Reports)
Source: Respirology Case Reports - April 28, 2023 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Adenocarcinoma with mediastinal lymph node involvement developed from a pure ground grass nodule during 14 years
We had an interesting case of a pure ground-glass nodule that developed into lung adenocarcinoma with mediastinal lymph node involvement over 14 years. Here we report the temporal change in the opacity of the GGN and the concept of image interpretation. AbstractA 69-year-old female Japanese patient presented with an abnormal shadow on chest computed tomography (CT). She had received a mastectomy 14 years prior. Under the diagnosis of primary lung cancer, left upper lobectomy was conducted. Pathology showed a lepidic adenocarcinoma with mediastinal lymph node metastases with pT2aN2M0. Upon retrospective analysis, the ...
Source: Respirology Case Reports - April 26, 2023 Category: Respiratory Medicine Authors: Hiroyuki Miura,
Jun Miura,
Shinichi Goto,
Tomoko Yamamoto Tags: CASE REPORT Source Type: research
