Severe heart failure due to peripartum cardiomyopathy
Perinatal cardiomyopathy develops during pregnancy or postpartum in women with no history of cardiac disease, presenting similarly to dilated cardiomyopathy. The pathogenesis is unknown but may be associated with both vascular damage and a genetic component. Physicians should consider pulmonary oedema due to perinatal cardiomyopathy in perinatal women with dyspnoea. Key messagePerinatal cardiomyopathy presents similarly to dilated cardiomyopathy and should be suspected in perinatal women presenting with dyspnoea, even with no previous history of heart disease. (Source: Respirology Case Reports)
Source: Respirology Case Reports - April 10, 2023 Category: Respiratory Medicine Authors: Haruhiko Michimata, Toshiyuki Sumi, Daiki Nagayama, Yuta Koshino, Hiroki Watanabe, Yuichi Yamada, Hirofumi Chiba Tags: CLINICAL IMAGE Source Type: research

An 83 ‐year‐old patient with RET fusion‐positive non‐small cell lung cancer experiencing severe hepatic disorder due to selpercatinib administration
We report a case of an old female patient with RET fusion-positive NSCLC who experienced severe hepatic disorder caused by selpercatinib. AbstractAn 83-year-old woman with RET fusion-positive advanced lung adenocarcinoma was administered selpercatinib 320  mg/day. Despite the shrinking of the tumour, fever, fatigue, and anorexia developed on day 17. Selpercatinib administration was interrupted. On day 21, elevated blood aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were observed. On day 28, AST and ALT levels increased to demo nstrate Grade 4 in CTCAE Ver.5. The patient received a glycyrrhizin-compo...
Source: Respirology Case Reports - April 10, 2023 Category: Respiratory Medicine Authors: Kazuhisa Nakashima, Yuki Mitarai, Seiko Tanaka, Mika Nakao, Takae Okuno, Tamio Okimoto, Ryo Tanabe, Takashi Yanagawa, Yukari Tsubata, Takeshi Isobe Tags: CASE REPORT Source Type: research

Severe COVID ‐19 pneumonia in pregnant woman treated with pulse corticosteroids therapy and third‐trimester caesarean section: A case report
In this case report, we present a critical COVID-19 case of a 44-year-old woman at 30  weeks of pregnancy. Her treatment was based on pulse corticosteroid therapy, accompanied by caesarean delivery. After nearly 1 month of hospitalization, with most of the time being in the intensive care unit, she was discharge and showed full recovery upon re-examination 10 months later. AbstractA 44-year-old woman at 30  weeks of pregnancy was admitted to the Intensive Care Unit with a diagnosis of severe COVID-19 pneumonia. Her condition worsened quickly, defined by prolonged hypoxia even with intensive therapy and oxygen supplem...
Source: Respirology Case Reports - April 5, 2023 Category: Respiratory Medicine Authors: Nghia Thinh Bui, Minh Nhat Huynh, Hung Tran, Dinh Kha Le, Tan Thanh Pham, Thanh Tung Pham, Tien Nhan Nguyen, Nguyen ‐Huy Do‐Tran, Hoang‐Anh Ngo, Thuy‐Anh Do Tags: CASE REPORT Source Type: research

Krukenberg tumour as the initial manifestation of lung adenocarcinoma
Krukenberg tumour from pulmonary malignancy represents an extremely rare situation. This is an elaboration of a case of young women with Krukenberg tumour rising from lung adenocarcinoma. AbstractKrukenberg tumours are unusual metastatic tumours of the ovary with primary tumours from the stomach, breast and gastrointestinal malignancies. Krukenberg tumour from pulmonary malignancy represents an extremely rare situation. This is an elaboration of a case of young women with Krukenberg tumour rising from lung adenocarcinoma. A 38-year-old woman presented with progressive abdominal distention for the past 2-years. Computed tom...
Source: Respirology Case Reports - April 5, 2023 Category: Respiratory Medicine Authors: Guat Yee Lim, Yen Shen Wong, Zahrah Tawil, Roqiah Fatmawati Abdul Kadir, Annamalai Ramanathan, Aisya Natasya Musa Tags: CASE REPORT Source Type: research

A case of bunashimeji mushroom ‐induced hypersensitivity pneumonitis diagnosed by inhalational provocation test in a hospital room
Hypersensitivity pneumonitis (HP) is an immunological disorder related to repeated inhalation of sensitizing allergens. Only a small number of reports have described HP caused by mushrooms. Here, we report a case of bunashimeji mushroom-induced HP, diagnosed by environmental provocation test and inhalational provocation test in a hospital room. AbstractA 66-year-old woman was admitted to our hospital with a 2-month history of dry cough and exertional dyspnea. She had worked as a mushroom farmer and had been exposed to mushroom for more than 40  years. The patient showed elevated levels of KL-6 (2966 U/mL) and surfactan...
Source: Respirology Case Reports - April 5, 2023 Category: Respiratory Medicine Authors: Tomoe Akagami, Kazuyuki Nakagome, Sotaro Takagi, Susumu Yamazaki, Shohei Minezaki, Hidetoshi Nakamura, Kenji Tsushima, Makoto Nagata Tags: CASE REPORT Source Type: research

Prolonged response to first ‐generation tyrosine kinase inhibitor in a metastatic non‐small cell lung cancer harbouring complex G719X and S768I mutations: A case report from Vietnam and literature review
In this study, we report a patient with metastatic non-small cell lung cancer carrying rare EGFR compound mutations of G719X and S768I who benefited from first-line treatment with gefitinib in Vietnam. This patient had a prolonged response lasting over 44  months with first-generation TKI. He continued to take gefitinib without experiencing serious adverse events. AbstractA complex ofG719X andS768I mutations is infrequently observed, constituting less than 0.3% of allEGFR-positive non-small cell lung cancer (NSCLC), and the response to first-line TKIs is inconsistent in the literature. In this study, we report a patient ...
Source: Respirology Case Reports - March 30, 2023 Category: Respiratory Medicine Authors: Kien Hung Do, Duc Thanh Le, Tai Van Nguyen, Tu Anh Do, Chu Van Nguyen Tags: CASE REPORT Source Type: research

Issue Information
(Source: Respirology Case Reports)
Source: Respirology Case Reports - March 29, 2023 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Tracheal stenosis following tracheotomy in a COVID ‐19 patient
We report a case of a 44-year-old female patient on maintenance haemodialysis who presented a COVID-19-related ARDS that required mechanical ventilation for 4  weeks, followed by a persistent stridor and finally succumbed, 1 month after being discharged from intensive care unit, from a severe respiratory distress due to a tracheal stenosis. Our aim is to highlight the importance of the early recognition and management of post tracheotomy stenosis in p atients with persistent respiratory difficulty as stridor after prolonged intubation requiring tracheotomy, in order to improve the prognosis of these patients. (Source: ...
Source: Respirology Case Reports - March 27, 2023 Category: Respiratory Medicine Authors: Mohamed Tayeb Salaouatchi, Linda Spinato, Said Sanoussi, Maria do Carmo Filomena Mesquita Tags: CASE REPORT Source Type: research

Use of the 1.1 mm cryoprobe through the radial EBUS GS (without the need for a bronchial blocker) to obtain samples safely in diagnosing PPL
We report two cases where the 1.1  mm cryoprobe was used and the cryobiopsy was extracted through the Radial EBUS GS whilst the bronchoscope remained in the bronchial tree with excellent control of bleeding due to the tamponading of the GS as well as the ability to attend to bleeding as soon as it occurred due to the bronchoscope being inside the airway. This method of obtaining the cryobiopsy through the GS and keeping the bronchoscope in the airway improved the safety of cryobiopsy for PPL. Further studies are required to assess the consistency of yield and safety of this method. AbstractCryobiopsy for peripheral pulmo...
Source: Respirology Case Reports - March 25, 2023 Category: Respiratory Medicine Authors: Samantha Herath Tags: CASE REPORT Source Type: research

Multiple complications of advanced IPF in an individual patient presentation
We report a patient with advanced idiopathic pulmonary fibrosis (IPF), who in a single presentation experienced three complications of the disease: an acute exacerbation, spontaneous pneumomediastinum, and platypnoea-orthodeoxia syndrome. Despite there being no definitive evidence-based treatment for an acute exacerbation, we report a marked improvement with high-dose steroids. This case also highlights the importance in IPF patients of considering pneumomediastinum as a cause of non-cardiac chest pain, as well as platypnoea-orthodeoxia in those with positional dyspnoea. AbstractWe report a patient with advanced idiopathic...
Source: Respirology Case Reports - March 24, 2023 Category: Respiratory Medicine Authors: Thomas Ledger, Stanley Braude Tags: CASE REPORT Source Type: research

Catheter ‐directed thrombolysis as an emergent intervention for failed vacuum thrombectomy of pulmonary embolism
We present such a scenario and the methods implored to successful remove clot burden. We add to the literature, use of catheter directed thrombolysis at a designated 2  mg/h rate as a form of emergent intervention in failed mechanical thrombectomy. (Source: Respirology Case Reports)
Source: Respirology Case Reports - March 24, 2023 Category: Respiratory Medicine Authors: Syed H. Haq, Jordan Hinegardner ‐Hendricks, Cliff Cole, Amanda Laird, Sidra R. Shah, Sandeep M. Patel, William Cole Tags: CASE REPORT Source Type: research

Cough remedy leading to chronic cough: An unusual airway foreign body ‐Clove
Clove has been used traditionally for its medicinal values and is commonly used as a cough remedy. In this case series, we report 4 cases of this unusual airway foreign body which were essentially consumed with an intention to prevent cough, but unfortunately became the reason for their cough. AbstractThe spectrum of presentation of airway foreign body can vary from having mild symptoms to sudden death. Smaller foreign body in distal airways, especially if the patient is unaware of aspiration can result in chronic symptoms mimicking asthma. Clove, has been used traditionally for its medicinal values and commonly used as a ...
Source: Respirology Case Reports - March 23, 2023 Category: Respiratory Medicine Authors: M. D. Varunn, R. Jayakumar, Chandrakant Tarke, Kishan Srikanth Juvva, D. Senthil Tags: CASE SERIES Source Type: research

Successful baricitinib treatment of refractory anti ‐synthetase syndrome associated with interstitial lung disease
We present a case of refractory ASS-ILD successfully treated with baricitinib after the failure of several other treatments. Bariticinib shows promise as a salvage treatment for patients with refractory ASS-ILD. AbstractA 47-year-old Japanese man was admitted with dyspnoea on exertion (DOE), skin rash and myalgia. Clinical findings of Gottron's sign and mechanic's hands were observed, with increased serum levels of Krebs von den Lungen-6, surfactant protein-D, creatine kinase, and anti-EJ on laboratory tests. In both lungs, chest computed tomography revealed diffuse reticular opacities and lower lobe predominance. The pati...
Source: Respirology Case Reports - March 22, 2023 Category: Respiratory Medicine Authors: Keishi Sugino, Hirotaka Ono, Mikako Saito, Masahiro Ando, Eiyasu Tsuboi Tags: CASE REPORT Source Type: research

Video ‐assisted surgical diagnosis and pleural adhesion management in catamenial pneumothorax: A case and literature review
We report a case of a 32-year-old woman with a history of endometriosis who presented to the emergency ward with a chief complaint of dyspnea and right-sided chest pain, and a chest X-ray showed a right pneumothorax. Initial management was by placing a chest tube to expand the right lung. The patient underwent a video-assisted thoracoscopy and talc pleurodesis, during which we found multiple perforations in the tendinous part of the diaphragm. A partial resection of the tendinous part of the diaphragm was done. Our review indicated that primary spontaneous pneumothorax in women should be suspected as catamenial pneumothora...
Source: Respirology Case Reports - March 22, 2023 Category: Respiratory Medicine Authors: Irandi Putra Pratomo, Muhammad Arza Putra, Lidia Giritri Bangun, Isti Mardiana Soetartio, Maria Angela Putri Maharani, Irene Sinta Febriana, Dicky Soehardiman, Prasenohadi Prasenohadi, Tutug Kinasih Tags: CASE REPORT Source Type: research

Difficult removal after bronchial filling of an endobronchial Watanabe spigot with N ‐butyl‐2‐cyanoacrylate for intractable pneumothorax: A case report
This case report, involves a 52-year-old man who had previously developed a right pneumothorax during treatment for COVID-19 and who we successfully treated through implanting four endobronchial Watanabe spigots (EWS) in the right B1 and B3 in two phases and spraying N-butyl-2-cyanoacrylate (NBCA), we report on the surgical and technical challenges we faced 12  months later, when the decision was made to remove the EWS. Therefore, careful consideration of the indications for this procedure is necessary. AbstractA 52-year-old man developed a right pneumothorax during treatment for COVID-19. In a previous case report conce...
Source: Respirology Case Reports - March 22, 2023 Category: Respiratory Medicine Authors: Tomoaki Nakamura, Shosei Ro, Chie Morita, Naoki Kanomata, Atsushi Kitamura Tags: CASE REPORT Source Type: research