Two cases of idiopathic pulmonary fibrosis evaluated by dynamic digital radiography for diaphragmatic motion and disease progression
Evaluation of diaphragmatic dynamics by dynamic digital radiography during non-effort tidal breathing in the supine position may be a promising method for predicting disease progression in patients with idiopathic pulmonary fibrosis. AbstractForced vital capacity has been utilized as a parameter of disease progression in idiopathic pulmonary fibrosis (IPF); however, its measurement is difficult when patients do not understand or cooperate. Dynamic digital radiography (DDR) enables sequential chest X-ray imaging during breathing, with lower radiation doses compared to conventional fluoroscopy or computed tomography. There i...
Source: Respirology Case Reports - February 22, 2024 Category: Respiratory Medicine Authors: Takefumi Nikaido, Yoshinori Tanino, Yuki Sato, Ryuichi Togawa, Takaya Kawamata, Natsumi Watanabe, Hiroyuki Minemura, Kojiro Ono, Katsumasa Sato, Yoko Shibata Tags: CASE REPORT Source Type: research

Steroid reduction ‐resistant pulmonary involvement with Sweet's syndrome suspected of being vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome: A case report
Few cases of lung lesions presenting with respiratory failure in Sweet's syndrome have been reported. We herein report a case of Sweet's syndrome in a patient suspected with VEXAS syndrome. AbstractIn cases of Sweet's syndrome with pulmonary involvement, fever of unknown origin, and macrocytic anaemia, VEXAS syndrome can be considered in the differential diagnosis. A 67-year-old man who was taking prednisolone for a fever of unknown origin and Sweet's syndrome was referred to us because of an abnormal chest shadow. Computed tomography revealed a nonfibrotic hypersensitivity pneumonitis-like opacity, and blood test results ...
Source: Respirology Case Reports - February 21, 2024 Category: Respiratory Medicine Authors: Yuki Amakusa, Tatsuro Suzuki, Masaya Takemura, Tetsuya Oguri Tags: CASE REPORT Source Type: research

Persistent cough and situs inversus in a middle ‐aged female
We present a case of diagnostic in adulthood in a female patient who presented with persistent productive cough and a history of recurrent pneumonias. Key messageKartagener syndrome, a rare genetic disorder, can present in adults with persistent respiratory symptoms and radiological changes, such as bronchiectasis and situs inversus. Clinicians should maintain a high clinical suspicion, as early recognition and appropriate management are crucial for preserving pulmonary function. (Source: Respirology Case Reports)
Source: Respirology Case Reports - February 21, 2024 Category: Respiratory Medicine Authors: Besharat Rahimi, Ghazal Roostaei, Hossein Kazemizadeh, Maryam Edalatifard, Niloofar Khoshnam ‐Rad Tags: CLINICAL IMAGE Source Type: research

Tracheopathia osteochondroplastica —A benign disorder with a daunting appearance
Tracheopathia osteochondroplastica (TO) is a rare and benign condition of the central airway, but with a daunting appearance. In this case report, we describe the clinical, imaging, and histological features, and videoed bronchoscopic findings, of a middle-aged male patient with incidentally diagnosed TO. AbstractTracheopathia osteochondroplastica (TO) is a rare and benign condition. It typically manifests as multiple osteocartilaginous nodules in the submucosa of the central airway. TO-related clinical symptoms and physical signs are nonspecific. The bronchoscopic examination is helpful in establishing the diagnosis. Trea...
Source: Respirology Case Reports - February 21, 2024 Category: Respiratory Medicine Authors: Chia ‐Hao Hu, Po‐Lan Su, Li‐Ting Huang, Chung‐Ta Lee, Tang‐Hsiu Huang Tags: CASE REPORT Source Type: research

Interstitial lung changes and persistent COVID ‐19 in a patient with follicular lymphoma: A case report
Herein, we report a case of COVID-19 persisting longer than 11  months which developed interstitial changes in the lungs that were recalcitrant to corticosteroid therapy. AbstractWe herein report a case of interstitial lung changes in a patient with prolonged coronavirus disease 2019 (COVID-19) with follicular lymphoma receiving rituximab and bendamustine who recovered after treatment with a combination therapy consisting of corticosteroids and immunosuppressive agents. There is currently no treatment strategy for prolonged pneumonitis following COVID-19, which can be life-threatening for immunocompromised patients. Thus...
Source: Respirology Case Reports - February 21, 2024 Category: Respiratory Medicine Authors: Makiko Yomota, Masaru Tanaka, Takayuki Kobayashi, Masatake Kitano, Saori Ikeda, Yusuke Kanemasa, Noriyo Yanagawa, Yukio Hosomi Tags: CASE REPORT Source Type: research

Isolated cryptococcal pleural effusion in a heart transplant recipient: A case report and literature review of pleural fluid adenosine deaminase levels
We report a case of isolated cryptococcal pleural effusion and review its characteristics with reference to pleural fluid adenosine deaminase (ADA) levels. AbstractIsolated cryptococcal pleural effusion is rare as the initial clinical presentation in opportunistic cryptococcal infection. We describe a 59-year-old male heart transplantation recipient who presented with a mononuclear-leukocyte-predominant exudative pleural effusion, with adenosine deaminase levels (ADA) of 37  IU/L and focal pleural nodularity on computed tomography. A thorough evaluation, including pleural fluid culture, cryptococcal antigen, and histolog...
Source: Respirology Case Reports - February 17, 2024 Category: Respiratory Medicine Authors: Jaehee Lee, Bo Eun Park, Se Yong Jang, Chang Ho Kim Tags: CASE REPORT Source Type: research

A chylothorax in a young woman: The difficulties of medical management
We describe a case of a complex patient with a LAM-related chylothorax, which was refractory to medical management. AbstractLymphangioleiomyomatosis is a rare pulmonary disease affecting women of childbearing age. Whilst chylothorax is a well-recognized complication of the condition, management strategies aren't well-defined, have low success rates and are often only available at tertiary or specialist centres. We describe a case of a young woman referred to pleural clinic with a chylous effusion found to be secondary to lymphangioleiomyomatosis. Initial medical management was unsuccessful and recurrent drainages caused si...
Source: Respirology Case Reports - February 16, 2024 Category: Respiratory Medicine Authors: Eleanor C. Barton, Simon Johnson, Neil Collin, Nidhi Bhatt, Nick A. Maskell Tags: CASE REPORT Source Type: research

COVID ‐19 organizing pneumonia with sudden dyspnea in an asymptomatic survivor
This case with post-covid pneumonia presented with sudden respiratory distress 5 weeks after recovery from COVID-19. Imaging showed generalized ground glass opacities (GGO) in both lungs with de-saturation. Respiratory symptoms  quickly and dramatically responded to steroid treatment and GGO significantly disappeared in just two days of treatment. Key messageThis case shows that COVID-19 survivors can develop delayed-type pneumonia with sudden respiratory distress that responds dramatically to steroid treatment after remaining asymptomatic for more than several weeks, although pulmonary involvement of post-COVID-19 syndro...
Source: Respirology Case Reports - February 15, 2024 Category: Respiratory Medicine Authors: Hwan Jin Lee, So Ri Kim Tags: CLINICAL IMAGE Source Type: research

A case of coagulation factor V inhibitor induced by immune checkpoint inhibitor therapy
In recent years, the use of immune checkpoint inhibitors (ICIs) for the treatment of various carcinomas has increased, which have been associated with immune-related adverse events (irAEs) that are often diverse. Haematological immune-related adverse events (hem-irAEs) are rare, and only a few cases of ICI-induced coagulation factor inhibitors have been reported. Here, we report a rare case of ICI-induced factor V inhibitor. AbstractA 73-year-old woman with lung adenocarcinoma (cT4N3M1a: Stage IVA) was treated with atezolizumab as the eighth line of therapy. Four weeks after the fourth dose of atezolizumab, the prothrombin...
Source: Respirology Case Reports - February 15, 2024 Category: Respiratory Medicine Authors: Yuki Haruta, Masanori Azuma, Toshikatsu Sado, Ryuichi Saito, Yoshimune Miyazaki, Akihiro Noda, Reina Kitagawa, Yasutaka Hori, Sayaka Fujimoto, Yoshinori Hasegawa, Tetsuya Ueda, Ryosuke Yamamura Tags: CASE REPORT Source Type: research

Chest drainage, a basic but essential procedure
We present within a case illustrating that, when properly implemented, it can successfully treat a severely ill patient and prevent surgical intervention. Key messageChest drainage is a basic and important procedure in the treatment of pneumothorax. When properly implemented, even the most severely ill patients may be able to be treated without surgical intervention. (Source: Respirology Case Reports)
Source: Respirology Case Reports - February 14, 2024 Category: Respiratory Medicine Authors: Masamitsu Hamakawa, Tadashi Ishida Tags: CLINICAL IMAGE Source Type: research

A case of allergic bronchopulmonary mycosis: 3D ‐CT Findings led to successful multidisciplinary treatment with dupilumab and cryoprobe
We report a successful treatment of allergic bronchopulmonary mycosis (ABPM) achieved via multidisciplinary treatment with dupilumab and a cryoprobe after visualizing mucus plugs obstructing the entire bronchus using three-dimensional (3D) computed tomography. AbstractThe present case involved a 78-year-old woman with repeated recurrences of allergic bronchopulmonary mycosis (ABPM) who presented to our outpatient clinic with a chief complaint of dyspnoea with respiratory failure. Computed tomography (CT) of the chest showed atelectasis of the lower lobes due to mucus plugs. Blood and biochemical tests showed a high periphe...
Source: Respirology Case Reports - February 14, 2024 Category: Respiratory Medicine Authors: Masamitsu Hamakawa, Takafumi Yamano, Machiko Arita, Takashi Niwa, Tadashi Ishida Tags: CASE REPORT Source Type: research

Extramural recurrence of tracheal glomus tumour following resection by rigid bronchoscopy
This report presents the case of a 67-year-old man who was referred to our institute for excision of a tracheal mass that had been found incidentally, and subsequently recurred extramurally. Initial contrast-enhanced computed tomography images of the chest revealed a nodular lesion in the trachea, 2.5  cm above the carina, that demonstrated strong enhancement similar to blood vessels. The tumour was excised by rigid bronchoscopy, but an extramural tracheal lesion was detected 18 months later. Tracheal resection and end-to-end anastomosis were performed, and histopathological examination confi rmed the extramural lesion...
Source: Respirology Case Reports - February 14, 2024 Category: Respiratory Medicine Authors: Makoto Takahama Tags: CASE REPORT Source Type: research

A case of hot tub lung secondary to mycobacterium avium complex in Victoria, Australia
We report the first case of hot tub lung in Victoria, Australia. AbstractHot tub lung (HTL) is a type of Hypersensitivity Pneumonitis (HP) caused by inhalation of aerosols containing non-tuberculous mycobacteria (NTM). We report the first case of hot tub lung in Victoria, Australia. A 31-year-old female presented with 3  weeks of dyspnoea, fevers and malaise, despite a course of antibiotics. She had used an indoor spa frequently for the past several months. She was hypoxic saturating 86% on room air. Examination revealed fine bilateral basal crepitations without wheeze. Inflammatory markers were elevated. A high resoluti...
Source: Respirology Case Reports - February 13, 2024 Category: Respiratory Medicine Authors: Louis Chhor, Reditta Soraya Tumali, Caroline Östberg, Anish Sachdev Tags: CASE REPORT Source Type: research

Pulmonary adenoid cystic carcinoma ‐ a spectrum of disease: two case reports
Although encountered infrequently in clinical practice, pulmonary adenoid cystic carcinoma is typically a slow-growing indolent condition however, a small proportion of patients present with acute, progressive symptoms and represent a diagnostic and therapeutic challenge. Novel treatments including proton beam therapy and 3D stent reconstruction have been successfully used in this cohort. AbstractAdenoid cystic carcinoma (ACC) is a rare form of adenocarcinoma that usually begins in the oral cavity, with most cases arising from the salivary glands. Owing to its low incidence, the precise clinical and pathological features, ...
Source: Respirology Case Reports - February 8, 2024 Category: Respiratory Medicine Authors: Margaret Gleeson, Megan Finan, Karen Redmond Tags: CASE REPORT Source Type: research

Bird ‐related non‐fibrotic hypersensitivity pneumonitis with bronchoalveolar lavage fluid eosinophilia that developed after COVID‐19 vaccination: A case report
Hypersensitivity pneumonitis (HP) is caused by exposure to an overt or occult inhaled antigens in susceptible individuals. Bird-related HP is now one of the major causes of HP. Several cases of eosinophilic pneumonia (EP) associated with the COVID-19 vaccination have been reported. Here, we report a case of non-fibrotic, bird-related HP with bronchoalveolar lavage fluid (BALF) eosinophilia equivalent to EP after COVID-19 vaccination. AbstractA 60-year-old man who had been keeping seven budgerigars and four cockatiels in his house for 2  years developed dyspnea and was admitted to our hospital the day after receiving the ...
Source: Respirology Case Reports - February 7, 2024 Category: Respiratory Medicine Authors: Takuma Katano, Tomoyuki Ogisu, Akira Satou, Toshiyuki Yonezawa, Hiroyuki Tanaka, Satoru Ito Tags: CASE REPORT Source Type: research