Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research
No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research
Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research
No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research
Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research
No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research
Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment
CONCLUSION: Adversities (particularly abuse) maximally influence the DMN during neurodevelopment and lead to the failure in the development of a coherent DMN system. While DMN's integrity is preserved in typical development, the age-dependent variability in atypically developing individuals is contrasting. The flexibility of DMN might be a compensatory mechanism to protect an individual in an abusive environment. However, such adaptability might deprive the neural system of the faculties of normal functioning and may incur long-term effects on the psyche.PMID:38509831 | DOI:10.1017/S0033291724000710 (Source: Psychological Medicine)
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Rajan Kashyap Bharath Holla Sagarika Bhattacharjee Eesha Sharma Urvakhsh Meherwan Mehta Nilakshi Vaidya Rose Dawn Bharath Pratima Murthy Debashish Basu Subodh Bhagyalakshmi Nanjayya Rajkumar Lenin Singh Roshan Lourembam Amit Chakrabarti Kamakshi Kartik Ka Source Type: research
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation
Psychol Med. 2024 Mar 21:1-9. doi: 10.1017/S0033291724000564. Online ahead of print.ABSTRACTRecent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that investigated the effects of meta-cognitive therapies on primary positive symptom outcomes, and secondar...
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Grace Melville Maeve Hoffman Alexia Pollock Matthew M Kurtz Source Type: research
Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment
CONCLUSION: Adversities (particularly abuse) maximally influence the DMN during neurodevelopment and lead to the failure in the development of a coherent DMN system. While DMN's integrity is preserved in typical development, the age-dependent variability in atypically developing individuals is contrasting. The flexibility of DMN might be a compensatory mechanism to protect an individual in an abusive environment. However, such adaptability might deprive the neural system of the faculties of normal functioning and may incur long-term effects on the psyche.PMID:38509831 | DOI:10.1017/S0033291724000710 (Source: Psychological Medicine)
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Rajan Kashyap Bharath Holla Sagarika Bhattacharjee Eesha Sharma Urvakhsh Meherwan Mehta Nilakshi Vaidya Rose Dawn Bharath Pratima Murthy Debashish Basu Subodh Bhagyalakshmi Nanjayya Rajkumar Lenin Singh Roshan Lourembam Amit Chakrabarti Kamakshi Kartik Ka Source Type: research
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation
Psychol Med. 2024 Mar 21:1-9. doi: 10.1017/S0033291724000564. Online ahead of print.ABSTRACTRecent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that investigated the effects of meta-cognitive therapies on primary positive symptom outcomes, and secondar...
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Grace Melville Maeve Hoffman Alexia Pollock Matthew M Kurtz Source Type: research
A subtype of schizophrenia patients with altered methylation level of genes related to immune cell activity
CONCLUSIONS: In summary, this study demonstrated a subtype of schizophrenia patients across both FES and LTS cohorts, defined by widespread alterations in methylation profile of genes related to immune function and distinguishing clinical features. This finding illustrates the promise of novel treatment strategies targeting immune dysregulation for a subpopulation of schizophrenia patients.PMID:38505948 | DOI:10.1017/S0033291724000667 (Source: Psychological Medicine)
Source: Psychological Medicine - March 20, 2024 Category: Psychiatry Authors: Chunyan Luo Xuenan Pi Qi Zhang Na Hu Yuan Xiao John A Sweeney Jeffrey R Bishop Qiyong Gong Dan Xie Su Lui Source Type: research
Additive effects of a family history of schizophrenia spectrum disorders and an environmental risk score for the outcome of patients with non-affective first-episode psychosis
CONCLUSIONS: Our results provide further empirical support regarding the contribution of FH-Sz to poor symptomatic remission and poor psychosocial functioning outcomes in patients with NAFEP.PMID:38505954 | DOI:10.1017/S0033291724000576 (Source: Psychological Medicine)
Source: Psychological Medicine - March 20, 2024 Category: Psychiatry Authors: Manuel J Cuesta Elena Garc ía de Jalón Ana M S ánchez-Torres Gustavo J Gil-Berrozpe Lidia Aranguren Gerardo Gutierrez Asier Corrales Amalia Zarzuela Berta Iba ñez V íctor Peralta PEPsNa Group Source Type: research
A subtype of schizophrenia patients with altered methylation level of genes related to immune cell activity
CONCLUSIONS: In summary, this study demonstrated a subtype of schizophrenia patients across both FES and LTS cohorts, defined by widespread alterations in methylation profile of genes related to immune function and distinguishing clinical features. This finding illustrates the promise of novel treatment strategies targeting immune dysregulation for a subpopulation of schizophrenia patients.PMID:38505948 | DOI:10.1017/S0033291724000667 (Source: Psychological Medicine)
Source: Psychological Medicine - March 20, 2024 Category: Psychiatry Authors: Chunyan Luo Xuenan Pi Qi Zhang Na Hu Yuan Xiao John A Sweeney Jeffrey R Bishop Qiyong Gong Dan Xie Su Lui Source Type: research
Additive effects of a family history of schizophrenia spectrum disorders and an environmental risk score for the outcome of patients with non-affective first-episode psychosis
CONCLUSIONS: Our results provide further empirical support regarding the contribution of FH-Sz to poor symptomatic remission and poor psychosocial functioning outcomes in patients with NAFEP.PMID:38505954 | DOI:10.1017/S0033291724000576 (Source: Psychological Medicine)
Source: Psychological Medicine - March 20, 2024 Category: Psychiatry Authors: Manuel J Cuesta Elena Garc ía de Jalón Ana M S ánchez-Torres Gustavo J Gil-Berrozpe Lidia Aranguren Gerardo Gutierrez Asier Corrales Amalia Zarzuela Berta Iba ñez V íctor Peralta PEPsNa Group Source Type: research
Comprehensive elucidation of resting-state functional connectivity in anorexia nervosa by a multicenter cross-sectional study
CONCLUSION: Stronger rsFCs in regions containing mainly DLPFC, and weaker rsFCs in regions containing primarily cerebellum, within temporal lobe, between posterior fusiform cortex and lateral part of visual network, and between ACC and thalamus, may represent categorical diagnostic markers discriminating AN patients from HC.PMID:38500410 | DOI:10.1017/S0033291724000485 (Source: Psychological Medicine)
Source: Psychological Medicine - March 19, 2024 Category: Psychiatry Authors: Yusuke Sudo Junko Ota Tsunehiko Takamura Rio Kamashita Sayo Hamatani Noriko Numata Ritu Bhusal Chhatkuli Tokiko Yoshida Jumpei Takahashi Hitomi Kitagawa Koji Matsumoto Yoshitada Masuda Michiko Nakazato Yasuhiro Sato Yumi Hamamoto Tomotaka Shoji Tomohiko M Source Type: research
