Using latent class analysis to investigate enduring effects of intersectional social disadvantage on long-term vocational and financial outcomes in the 20-year prospective Chicago Longitudinal Study
CONCLUSIONS: Our analyses add to a growing literature on the impact of multiple forms of social disadvantage on long-term functional trajectories, underscoring the importance of proactive attention to sociostructural disadvantage early in treatment, and the development and evaluation of interventions designed to mitigate ongoing social stratification.PMID:38523254 | DOI:10.1017/S0033291724000588 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Nev Jones Liping Tong Shannon Pagdon Ikenna D Ebuenyi Martin Harrow Rajiv P Sharma Cherise Rosen Source Type: research
Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews
Psychol Med. 2024 Mar 25:1-25. doi: 10.1017/S0033291724000333. Online ahead of print.ABSTRACTGlobally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review of reviews to examine the evidence base for interventions that map onto the UN SDGs and seek to improve mental health through targeting known social determinants ...
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Tassia Kate Oswald Minh Thu Nguyen Luwaiza Mirza Crick Lund Hannah Grace Jones Grace Crowley Daron Aslanyan Kimberlie Dean Peter Schofield Matthew Hotopf Jayati Das-Munshi Source Type: research
Dynamic aberrances of substantia nigra-relevant coactivation patterns in first-episode treatment-na ïve patients with schizophrenia
CONCLUSION: Our results suggest that neuroregulatory dysfunction in dopaminergic pathways involving SN potentially mediates aberrant time-varying functional reorganizations in schizophrenia. This finding enriches the dopamine hypothesis of schizophrenia from the perspective of brain dynamics.PMID:38523252 | DOI:10.1017/S0033291724000655 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Lihong Deng Wei Wei Chunxia Qiao Yubing Yin Xiaojing Li Hua Yu Lingqi Jian Xiaohong Ma Liansheng Zhao Qiang Wang Wei Deng Wanjun Guo Tao Li Source Type: research
Using latent class analysis to investigate enduring effects of intersectional social disadvantage on long-term vocational and financial outcomes in the 20-year prospective Chicago Longitudinal Study
CONCLUSIONS: Our analyses add to a growing literature on the impact of multiple forms of social disadvantage on long-term functional trajectories, underscoring the importance of proactive attention to sociostructural disadvantage early in treatment, and the development and evaluation of interventions designed to mitigate ongoing social stratification.PMID:38523254 | DOI:10.1017/S0033291724000588 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Nev Jones Liping Tong Shannon Pagdon Ikenna D Ebuenyi Martin Harrow Rajiv P Sharma Cherise Rosen Source Type: research
Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research
No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research
Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research
No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research
Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research
No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research
Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment
CONCLUSION: Adversities (particularly abuse) maximally influence the DMN during neurodevelopment and lead to the failure in the development of a coherent DMN system. While DMN's integrity is preserved in typical development, the age-dependent variability in atypically developing individuals is contrasting. The flexibility of DMN might be a compensatory mechanism to protect an individual in an abusive environment. However, such adaptability might deprive the neural system of the faculties of normal functioning and may incur long-term effects on the psyche.PMID:38509831 | DOI:10.1017/S0033291724000710 (Source: Psychological Medicine)
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Rajan Kashyap Bharath Holla Sagarika Bhattacharjee Eesha Sharma Urvakhsh Meherwan Mehta Nilakshi Vaidya Rose Dawn Bharath Pratima Murthy Debashish Basu Subodh Bhagyalakshmi Nanjayya Rajkumar Lenin Singh Roshan Lourembam Amit Chakrabarti Kamakshi Kartik Ka Source Type: research
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation
Psychol Med. 2024 Mar 21:1-9. doi: 10.1017/S0033291724000564. Online ahead of print.ABSTRACTRecent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that investigated the effects of meta-cognitive therapies on primary positive symptom outcomes, and secondar...
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Grace Melville Maeve Hoffman Alexia Pollock Matthew M Kurtz Source Type: research
Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment
CONCLUSION: Adversities (particularly abuse) maximally influence the DMN during neurodevelopment and lead to the failure in the development of a coherent DMN system. While DMN's integrity is preserved in typical development, the age-dependent variability in atypically developing individuals is contrasting. The flexibility of DMN might be a compensatory mechanism to protect an individual in an abusive environment. However, such adaptability might deprive the neural system of the faculties of normal functioning and may incur long-term effects on the psyche.PMID:38509831 | DOI:10.1017/S0033291724000710 (Source: Psychological Medicine)
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Rajan Kashyap Bharath Holla Sagarika Bhattacharjee Eesha Sharma Urvakhsh Meherwan Mehta Nilakshi Vaidya Rose Dawn Bharath Pratima Murthy Debashish Basu Subodh Bhagyalakshmi Nanjayya Rajkumar Lenin Singh Roshan Lourembam Amit Chakrabarti Kamakshi Kartik Ka Source Type: research
Do metacognitive therapies for schizophrenia-spectrum disorders work? A meta-analytic investigation
Psychol Med. 2024 Mar 21:1-9. doi: 10.1017/S0033291724000564. Online ahead of print.ABSTRACTRecent reviews and meta-analyses of metacognitive therapy for schizophrenia-spectrum disorder (SSD) have included uncontrolled studies, single-session interventions, and/or analyses limited to a single form of metacognitive therapy. We sought to evaluate the efficacy of metacognitive therapies more broadly based on controlled trials (CT) of sustained treatments. We conducted a pre-registered meta-analysis of controlled trials that investigated the effects of meta-cognitive therapies on primary positive symptom outcomes, and secondar...
Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Grace Melville Maeve Hoffman Alexia Pollock Matthew M Kurtz Source Type: research
A subtype of schizophrenia patients with altered methylation level of genes related to immune cell activity
CONCLUSIONS: In summary, this study demonstrated a subtype of schizophrenia patients across both FES and LTS cohorts, defined by widespread alterations in methylation profile of genes related to immune function and distinguishing clinical features. This finding illustrates the promise of novel treatment strategies targeting immune dysregulation for a subpopulation of schizophrenia patients.PMID:38505948 | DOI:10.1017/S0033291724000667 (Source: Psychological Medicine)
Source: Psychological Medicine - March 20, 2024 Category: Psychiatry Authors: Chunyan Luo Xuenan Pi Qi Zhang Na Hu Yuan Xiao John A Sweeney Jeffrey R Bishop Qiyong Gong Dan Xie Su Lui Source Type: research
