A subtype of schizophrenia patients with altered methylation level of genes related to immune cell activity

CONCLUSIONS: In summary, this study demonstrated a subtype of schizophrenia patients across both FES and LTS cohorts, defined by widespread alterations in methylation profile of genes related to immune function and distinguishing clinical features. This finding illustrates the promise of novel treatment strategies targeting immune dysregulation for a subpopulation of schizophrenia patients.PMID:38505948 | DOI:10.1017/S0033291724000667

Source: Psychological Medicine - March 20, 2024 Category: Psychiatry Authors: Chunyan Luo Xuenan Pi Qi Zhang Na Hu Yuan Xiao John A Sweeney Jeffrey R Bishop Qiyong Gong Dan Xie Su Lui Source Type: research