Associations between attention-deficit hyperactivity disorder genetic liability and ICD-10 medical conditions in adults: utilizing electronic health records in a Phenome-Wide Association Study
CONCLUSIONS: Overall our findings indicate that ADHD genetic liability is associated with an increased risk of a substantial number of medical conditions in undiagnosed individuals. These results highlight the need for timely detection and improved management of ADHD symptoms in adults.PMID:38563284 | DOI:10.1017/S0033291724000606 (Source: Psychological Medicine)
Source: Psychological Medicine - April 2, 2024 Category: Psychiatry Authors: Elis Haan Kristi Krebs Urmo V õsa Isabell Brikell Henrik Larsson Estonian Biobank Research Team Kelli Lehto Source Type: research
Relative associations of behavioral and physiological risks for cardiometabolic disease with cognition in bipolar disorder during mid and later-life: findings from the UK biobank
CONCLUSIONS: Health risk behaviors, as well as blood pressure and muscular strength, are associated with cognitive function in BD, whereas other traditional physiological cardiometabolic disease risk factors are not.PMID:38563285 | DOI:10.1017/S0033291724000722 (Source: Psychological Medicine)
Source: Psychological Medicine - April 2, 2024 Category: Psychiatry Authors: Elysha Ringin David W Dunstan Denny Meyer Roger S McIntyre Neville Owen Michael Berk Mats Hallgren Susan L Rossell Tamsyn E Van Rheenen Source Type: research
Clinical illness course and family-related outcomes among parents with a first episode of schizophrenia spectrum disorder: a 20-year follow-up of the OPUS trial
CONCLUSIONS: Overall, parents have more favorable long-term outcomes than non-parents. Still, parents experience possible challenges regarding family functioning, and a minority of their children face difficulties in daily life.PMID:38563286 | DOI:10.1017/S0033291724000680 (Source: Psychological Medicine)
Source: Psychological Medicine - April 2, 2024 Category: Psychiatry Authors: Helene Gjervig Hansen Ida Christine Tholstrup Gj øde Marie Starzer Anne Ranning Carsten Hjorth øj Nikolai Albert Merete Nordentoft Anne Amalie Elgaard Thorup Source Type: research
The mediating role of reflective functioning and general psychopathology in the relationship between childhood conduct disorder and adult aggression among offenders
CONCLUSIONS: These findings highlight the critical role of a transdiagnostic approach provided by RF and general psychopathology in explaining the link between CD and aggression. Furthermore, they underscore the potential utility of treatments focusing on RF, such as mentalization-based treatment, in mitigating aggression in offenders with diverse psychopathologies.PMID:38563288 | DOI:10.1017/S003329172400062X (Source: Psychological Medicine)
Source: Psychological Medicine - April 2, 2024 Category: Psychiatry Authors: Karen Yirmiya Matthew Constantinou Elizabeth Simes Anthony Bateman James Wason Jessica Yakeley Mary McMurran Mike Crawford Alison Frater Paul Moran Barbara Barrett Angus Cameron Zoe Hoare Elizabeth Allison Stephen Pilling Stephen Butler Peter Fonagy Source Type: research
Age-atypical brain functional networks in autism spectrum disorder: a normative modeling approach
CONCLUSIONS: Individuals with ASD exhibit distinct, highly individualized trajectories of brain functional network development. In addition, distinct developmental trajectories were observed among ASD and TD individuals, suggesting that it may be challenging to identify true differences in network characteristics by comparing young children with ASD to their TD peers. This study enhances understanding of the biological heterogeneity of the disorder and can inform precision medicine.PMID:38563297 | DOI:10.1017/S0033291724000138 (Source: Psychological Medicine)
Source: Psychological Medicine - April 2, 2024 Category: Psychiatry Authors: Anhang Jiang Xuefeng Ma Shuang Li Lingxiao Wang Bo Yang Shizhen Wang Mei Li Guangheng Dong Source Type: research
Assessing regional intracortical myelination in schizophrenia spectrum and bipolar disorders using the optimized T1w/T2w-ratio
CONCLUSIONS: While we found no evidence of reduced intracortical myelin in SCZ or BPD relative to CTR, different regional age trajectories in SCZ may suggest a promyelinating effect of antipsychotic medication.PMID:38563302 | DOI:10.1017/S0033291724000503 (Source: Psychological Medicine)
Source: Psychological Medicine - April 2, 2024 Category: Psychiatry Authors: Kjetil Nordb ø Jørgensen Stener Nerland Nora Berz Slap ø Linn B Norbom Lynn M ørch-Johnsen Laura Anne Wortinger Claudia Barth Dimitrios Andreou Ivan I Maximov Oliver M Geier Ole A Andreassen Erik G J önsson Ingrid Agartz Source Type: research
The stability and change of wellbeing across the lifespan: a longitudinal twin-sibling study
CONCLUSION: These findings provide insights into the stability and change of wellbeing and the genetic and environmental influences across the lifespan. Genetic effects were mostly stable, except in adolescence, whereas the environmental innovation at every age suggests that changing environmental factors are a source of changes in individual differences in wellbeing over time.PMID:38533784 | DOI:10.1017/S0033291724000692 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Lianne P de Vries Dirk H M Pelt Meike Bartels Source Type: research
Adaptive-to-maladaptive gradient of emotion regulation tendencies are embedded in the functional-structural hybrid connectome
CONCLUSIONS: Taken together, our study illustrates a gradient of emotion regulation tendencies that is best captured when simultaneously considering the functional and structural connections across the whole brain.PMID:38533787 | DOI:10.1017/S0033291724000473 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Wonyoung Kim M Justin Kim Source Type: research
Optimizing precision medicine for second-step depression treatment: a machine learning approach
CONCLUSION: Ensemble machine learning has potential to predict second-step treatment. In this study, predictive performance varied by type of treatment, with greater accuracy in predicting remission in response to behavioral treatments than to pharmacotherapy interventions. Future directions include considering more informative predictor modalities to enhance prediction of second-step treatment response.PMID:38533794 | DOI:10.1017/S0033291724000497 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Joshua Curtiss Jordan W Smoller Paola Pedrelli Source Type: research
The stability and change of wellbeing across the lifespan: a longitudinal twin-sibling study
CONCLUSION: These findings provide insights into the stability and change of wellbeing and the genetic and environmental influences across the lifespan. Genetic effects were mostly stable, except in adolescence, whereas the environmental innovation at every age suggests that changing environmental factors are a source of changes in individual differences in wellbeing over time.PMID:38533784 | DOI:10.1017/S0033291724000692 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Lianne P de Vries Dirk H M Pelt Meike Bartels Source Type: research
Adaptive-to-maladaptive gradient of emotion regulation tendencies are embedded in the functional-structural hybrid connectome
CONCLUSIONS: Taken together, our study illustrates a gradient of emotion regulation tendencies that is best captured when simultaneously considering the functional and structural connections across the whole brain.PMID:38533787 | DOI:10.1017/S0033291724000473 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Wonyoung Kim M Justin Kim Source Type: research
Optimizing precision medicine for second-step depression treatment: a machine learning approach
CONCLUSION: Ensemble machine learning has potential to predict second-step treatment. In this study, predictive performance varied by type of treatment, with greater accuracy in predicting remission in response to behavioral treatments than to pharmacotherapy interventions. Future directions include considering more informative predictor modalities to enhance prediction of second-step treatment response.PMID:38533794 | DOI:10.1017/S0033291724000497 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Joshua Curtiss Jordan W Smoller Paola Pedrelli Source Type: research
The stability and change of wellbeing across the lifespan: a longitudinal twin-sibling study
CONCLUSION: These findings provide insights into the stability and change of wellbeing and the genetic and environmental influences across the lifespan. Genetic effects were mostly stable, except in adolescence, whereas the environmental innovation at every age suggests that changing environmental factors are a source of changes in individual differences in wellbeing over time.PMID:38533784 | DOI:10.1017/S0033291724000692 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Lianne P de Vries Dirk H M Pelt Meike Bartels Source Type: research
Adaptive-to-maladaptive gradient of emotion regulation tendencies are embedded in the functional-structural hybrid connectome
CONCLUSIONS: Taken together, our study illustrates a gradient of emotion regulation tendencies that is best captured when simultaneously considering the functional and structural connections across the whole brain.PMID:38533787 | DOI:10.1017/S0033291724000473 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Wonyoung Kim M Justin Kim Source Type: research
Optimizing precision medicine for second-step depression treatment: a machine learning approach
CONCLUSION: Ensemble machine learning has potential to predict second-step treatment. In this study, predictive performance varied by type of treatment, with greater accuracy in predicting remission in response to behavioral treatments than to pharmacotherapy interventions. Future directions include considering more informative predictor modalities to enhance prediction of second-step treatment response.PMID:38533794 | DOI:10.1017/S0033291724000497 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Joshua Curtiss Jordan W Smoller Paola Pedrelli Source Type: research
