The stability and change of wellbeing across the lifespan: a longitudinal twin-sibling study
CONCLUSION: These findings provide insights into the stability and change of wellbeing and the genetic and environmental influences across the lifespan. Genetic effects were mostly stable, except in adolescence, whereas the environmental innovation at every age suggests that changing environmental factors are a source of changes in individual differences in wellbeing over time.PMID:38533784 | DOI:10.1017/S0033291724000692 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Lianne P de Vries Dirk H M Pelt Meike Bartels Source Type: research

Adaptive-to-maladaptive gradient of emotion regulation tendencies are embedded in the functional-structural hybrid connectome
CONCLUSIONS: Taken together, our study illustrates a gradient of emotion regulation tendencies that is best captured when simultaneously considering the functional and structural connections across the whole brain.PMID:38533787 | DOI:10.1017/S0033291724000473 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Wonyoung Kim M Justin Kim Source Type: research

Optimizing precision medicine for second-step depression treatment: a machine learning approach
CONCLUSION: Ensemble machine learning has potential to predict second-step treatment. In this study, predictive performance varied by type of treatment, with greater accuracy in predicting remission in response to behavioral treatments than to pharmacotherapy interventions. Future directions include considering more informative predictor modalities to enhance prediction of second-step treatment response.PMID:38533794 | DOI:10.1017/S0033291724000497 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Joshua Curtiss Jordan W Smoller Paola Pedrelli Source Type: research

The stability and change of wellbeing across the lifespan: a longitudinal twin-sibling study
CONCLUSION: These findings provide insights into the stability and change of wellbeing and the genetic and environmental influences across the lifespan. Genetic effects were mostly stable, except in adolescence, whereas the environmental innovation at every age suggests that changing environmental factors are a source of changes in individual differences in wellbeing over time.PMID:38533784 | DOI:10.1017/S0033291724000692 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Lianne P de Vries Dirk H M Pelt Meike Bartels Source Type: research

Adaptive-to-maladaptive gradient of emotion regulation tendencies are embedded in the functional-structural hybrid connectome
CONCLUSIONS: Taken together, our study illustrates a gradient of emotion regulation tendencies that is best captured when simultaneously considering the functional and structural connections across the whole brain.PMID:38533787 | DOI:10.1017/S0033291724000473 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Wonyoung Kim M Justin Kim Source Type: research

Optimizing precision medicine for second-step depression treatment: a machine learning approach
CONCLUSION: Ensemble machine learning has potential to predict second-step treatment. In this study, predictive performance varied by type of treatment, with greater accuracy in predicting remission in response to behavioral treatments than to pharmacotherapy interventions. Future directions include considering more informative predictor modalities to enhance prediction of second-step treatment response.PMID:38533794 | DOI:10.1017/S0033291724000497 (Source: Psychological Medicine)
Source: Psychological Medicine - March 27, 2024 Category: Psychiatry Authors: Joshua Curtiss Jordan W Smoller Paola Pedrelli Source Type: research

Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews
Psychol Med. 2024 Mar 25:1-25. doi: 10.1017/S0033291724000333. Online ahead of print.ABSTRACTGlobally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review of reviews to examine the evidence base for interventions that map onto the UN SDGs and seek to improve mental health through targeting known social determinants ...
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Tassia Kate Oswald Minh Thu Nguyen Luwaiza Mirza Crick Lund Hannah Grace Jones Grace Crowley Daron Aslanyan Kimberlie Dean Peter Schofield Matthew Hotopf Jayati Das-Munshi Source Type: research

Dynamic aberrances of substantia nigra-relevant coactivation patterns in first-episode treatment-na ïve patients with schizophrenia
CONCLUSION: Our results suggest that neuroregulatory dysfunction in dopaminergic pathways involving SN potentially mediates aberrant time-varying functional reorganizations in schizophrenia. This finding enriches the dopamine hypothesis of schizophrenia from the perspective of brain dynamics.PMID:38523252 | DOI:10.1017/S0033291724000655 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Lihong Deng Wei Wei Chunxia Qiao Yubing Yin Xiaojing Li Hua Yu Lingqi Jian Xiaohong Ma Liansheng Zhao Qiang Wang Wei Deng Wanjun Guo Tao Li Source Type: research

Using latent class analysis to investigate enduring effects of intersectional social disadvantage on long-term vocational and financial outcomes in the 20-year prospective Chicago Longitudinal Study
CONCLUSIONS: Our analyses add to a growing literature on the impact of multiple forms of social disadvantage on long-term functional trajectories, underscoring the importance of proactive attention to sociostructural disadvantage early in treatment, and the development and evaluation of interventions designed to mitigate ongoing social stratification.PMID:38523254 | DOI:10.1017/S0033291724000588 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Nev Jones Liping Tong Shannon Pagdon Ikenna D Ebuenyi Martin Harrow Rajiv P Sharma Cherise Rosen Source Type: research

Interventions targeting social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews
Psychol Med. 2024 Mar 25:1-25. doi: 10.1017/S0033291724000333. Online ahead of print.ABSTRACTGlobally, mental disorders account for almost 20% of disease burden and there is growing evidence that mental disorders are socially determined. Tackling the United Nations Sustainable Development Goals (UN SDGs), which address social determinants of mental disorders, may be an effective way to reduce the global burden of mental disorders. We conducted a systematic review of reviews to examine the evidence base for interventions that map onto the UN SDGs and seek to improve mental health through targeting known social determinants ...
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Tassia Kate Oswald Minh Thu Nguyen Luwaiza Mirza Crick Lund Hannah Grace Jones Grace Crowley Daron Aslanyan Kimberlie Dean Peter Schofield Matthew Hotopf Jayati Das-Munshi Source Type: research

Dynamic aberrances of substantia nigra-relevant coactivation patterns in first-episode treatment-na ïve patients with schizophrenia
CONCLUSION: Our results suggest that neuroregulatory dysfunction in dopaminergic pathways involving SN potentially mediates aberrant time-varying functional reorganizations in schizophrenia. This finding enriches the dopamine hypothesis of schizophrenia from the perspective of brain dynamics.PMID:38523252 | DOI:10.1017/S0033291724000655 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Lihong Deng Wei Wei Chunxia Qiao Yubing Yin Xiaojing Li Hua Yu Lingqi Jian Xiaohong Ma Liansheng Zhao Qiang Wang Wei Deng Wanjun Guo Tao Li Source Type: research

Using latent class analysis to investigate enduring effects of intersectional social disadvantage on long-term vocational and financial outcomes in the 20-year prospective Chicago Longitudinal Study
CONCLUSIONS: Our analyses add to a growing literature on the impact of multiple forms of social disadvantage on long-term functional trajectories, underscoring the importance of proactive attention to sociostructural disadvantage early in treatment, and the development and evaluation of interventions designed to mitigate ongoing social stratification.PMID:38523254 | DOI:10.1017/S0033291724000588 (Source: Psychological Medicine)
Source: Psychological Medicine - March 25, 2024 Category: Psychiatry Authors: Nev Jones Liping Tong Shannon Pagdon Ikenna D Ebuenyi Martin Harrow Rajiv P Sharma Cherise Rosen Source Type: research

Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research

No relationship between male pubertal timing and depression - new insights from epidemiology and Mendelian randomization
CONCLUSIONS: Pubertal timing is not related to MDD risk in males.PMID:38515277 | DOI:10.1017/S0033291724000060 (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Raphael Hirtz Corinna Grasemann Heike H ölling Bj örn-Hergen von Holt Nicola Albers Anke Hinney Johannes Hebebrand Triinu Peters Source Type: research

Structural and resting-state connection abnormalities of habenula in obsessive-compulsive disorder
CONCLUSIONS: This study suggested that abnormal structure of Hb and hippocampus-Hb connectivity may contribute to the pathological basis of OCD.PMID:38515276 | DOI:10.1017/S003329172400045X (Source: Psychological Medicine)
Source: Psychological Medicine - March 22, 2024 Category: Psychiatry Authors: Qian Liu Xiang Wang Yanyuan Cao Feng Gao Jie Xia Hongyu Du Haiyan Liao Changlian Tan Jie Fan Xiongzhao Zhu Source Type: research