Childhood adversities characterize the heterogeneity in the brain pattern of individuals during neurodevelopment

CONCLUSION: Adversities (particularly abuse) maximally influence the DMN during neurodevelopment and lead to the failure in the development of a coherent DMN system. While DMN's integrity is preserved in typical development, the age-dependent variability in atypically developing individuals is contrasting. The flexibility of DMN might be a compensatory mechanism to protect an individual in an abusive environment. However, such adaptability might deprive the neural system of the faculties of normal functioning and may incur long-term effects on the psyche.PMID:38509831 | DOI:10.1017/S0033291724000710

Source: Psychological Medicine - March 21, 2024 Category: Psychiatry Authors: Rajan Kashyap Bharath Holla Sagarika Bhattacharjee Eesha Sharma Urvakhsh Meherwan Mehta Nilakshi Vaidya Rose Dawn Bharath Pratima Murthy Debashish Basu Subodh Bhagyalakshmi Nanjayya Rajkumar Lenin Singh Roshan Lourembam Amit Chakrabarti Kamakshi Kartik Ka Source Type: research