Diagnosis and Treatment of Cervical Spondylotic Radiculopathy Using Selective Nerve Root Block (SNRB): Where are We Now?
AbstractCervical spondylotic radiculopathy (CSR) is one of the most common degenerative diseases of the spine that is commonly treated with surgery. The primary goal of surgery is to relieve symptoms through decompression or relieving pressure on compressed cervical nerves. Nevertheless, cutaneous pain distribution is not always predictable, making accurate diagnosis challenging and increasing the likelihood of inadequate surgical outcomes. With the widespread application of minimally invasive surgical techniques, the requirement for precise preoperative localization of the affected segments has become critical, especially...
Source: Pain and Therapy - February 15, 2022 Category: Anesthesiology Source Type: research
Perioperative Dexmedetomidine or Lidocaine Infusion for the Prevention of Chronic Postoperative and Neuropathic Pain After Gynecological Surgery: A Randomized, Placebo-Controlled, Double-Blind Study
ConclusionsDexmedetomidine was superior to placebo regarding the duration and severity of CPP, while lidocaine exhibited a protective effect against neuropathic elements of CPP.Trial registrationClinicalTrials.gov identifier, NCT03363425. (Source: Pain and Therapy)
Source: Pain and Therapy - February 15, 2022 Category: Anesthesiology Source Type: research
Pain and Therapy in the Realm of a Storm
(Source: Pain and Therapy)
Source: Pain and Therapy - February 12, 2022 Category: Anesthesiology Source Type: research
The Effect of M-Health-Based Core Stability Exercise Combined with Self-Compassion Training for Patients with Nonspecific Chronic Low Back Pain: A Randomized Controlled Pilot Study
ConclusionsThe pilot study is feasible to deliver, and our results indicate that participants in the group of m-health-based CSE combined with SCT may experience faster relief from pain intensity and back disability than those in the group of m-health-based CSE alone.Trial RegistrationChiCTR2100042810. (Source: Pain and Therapy)
Source: Pain and Therapy - February 8, 2022 Category: Anesthesiology Source Type: research
Diagnostic and Predictive Capacity of the Spanish Versions of the Opioid Risk Tool and the Screener and Opioid Assessment for Patients with Pain —Revised: A Preliminary Investigation in a Sample of People with Noncancer Chronic Pain
ConclusionIn the setting of Spanish-speaking communities, clinicians should be cautious when using these instruments to make decisions on opioid administration. Further research is needed on the diagnostic and predictive capacity of the Spanish versions of both instruments. (Source: Pain and Therapy)
Source: Pain and Therapy - February 7, 2022 Category: Anesthesiology Source Type: research
Opioid-Induced Constipation in Real-World Practice: A Physician Survey, 1 Year Later
ConclusionsDespite some limitations, our study demonstrated a slow but important step closer to standardization of diagnosis and treatment of OIC. Further educational and training efforts should be put in place to favor best evidence-based clinical practice. (Source: Pain and Therapy)
Source: Pain and Therapy - February 5, 2022 Category: Anesthesiology Source Type: research
Genetic and Clinical Factors Associated with Opioid Response in Chinese Han Patients with Cancer Pain: An Exploratory Cross-Sectional Study
ConclusionsThis study reveals for the first time that construction of multidimensional gene –environment interactions enables better interpretations of the effect of genetic variation and environmental factors on the opioid response in patients with cancer pain.Trial registrationChictr.org.cn, identifier, ChiCTR2000033576. (Source: Pain and Therapy)
Source: Pain and Therapy - February 2, 2022 Category: Anesthesiology Source Type: research
Racial Differences in Pain, Nutrition, and Oxidative Stress
AbstractInvestigating the disproportionate rates of chronic pain and their related comorbidities between Black and non-Hispanic White (White) individuals is a growing area of interest, both in the healthcare community and in general society. Researchers have identified racial differences in chronic pain prevalence and severity, but still very little is known about the mechanisms underlying them. Current explanations for these differences have primarily focused on socioeconomic status and unequal healthcare between races as causal factors. Whereas these factors are informative, a racial gap still exists between Black and Wh...
Source: Pain and Therapy - February 1, 2022 Category: Anesthesiology Source Type: research
Development of a Model for Predicting the Effectiveness of Pulsed Radiofrequency on Zoster-Associated Pain
ConclusionsSeven factors were significantly associated with poor PRF outcome: male sex, advanced stage of HZ, higher pregabalin dose, higher bodily pain indicators of SF-36, and lower lymphocyte count, LDLC, and complement C4 in the peripheral blood. PRF should be applied to patients with ZAP as early as possible to achieve satisfactory outcomes. (Source: Pain and Therapy)
Source: Pain and Therapy - January 30, 2022 Category: Anesthesiology Source Type: research
Pharmacist-Led Management Improves Treatment Adherence and Quality of Life in Opioid-Tolerant Patients With Cancer Pain: A Randomized Controlled Trial
ConclusionsPharmacist-led management improved treatment adherence, quality of life, and the reporting of adverse events in opioid-tolerant patients with cancer pain.Trial RegistrationClinicalTrials.gov, NCT03455023. (Source: Pain and Therapy)
Source: Pain and Therapy - January 29, 2022 Category: Anesthesiology Source Type: research
Clinical and Radiographic Outcomes of Combined Posterior Transfacet Screw Fixation and Anterior Cervical Discectomy and Fusion Surgery for Unilateral Cervical Facet Fracture with Traumatic Disc Herniation: A Retrospective Cohort Study
ConclusionIn the absence of any self-evident clinical and radiographic benefits of one technique over the other (TFS + ACDF vs. LMSR + ACDF), we recommend combined TFS + ACDF surgery as a safe and less invasive alternative treatment for unilateral cervical facet fractures with traumatic disc herniation, as it was associated with a shorter duration of surgery and lower estimated blood loss than LMSR + ACDF surgery. (Source: Pain and Therapy)
Source: Pain and Therapy - January 22, 2022 Category: Anesthesiology Source Type: research
A Response to: Letter to the Editor Regarding “Gabapentin has Longer-Term Efficacy for the Treatment of Chronic Pelvic Pain in Women: A Systematic Review and Pilot Meta-analysis”
(Source: Pain and Therapy)
Source: Pain and Therapy - January 19, 2022 Category: Anesthesiology Source Type: research
Letter to the Editor Regarding “Gabapentin has Longer-Term Efficacy for the Treatment of Chronic Pelvic Pain in Women: A Systematic Review and Pilot Meta-analysis”
(Source: Pain and Therapy)
Source: Pain and Therapy - January 19, 2022 Category: Anesthesiology Source Type: research
Opioids for Treatment of Pre-hospital Acute Pain: A Systematic Review
ConclusionsAvailable evidence for pre-hospital opioid administration to relieve acute pain is scarce and the overall quality of evidence is low. Intravenous administration of synthetic, fast-acting opioids may be as effective and safe as intravenous administration of morphine. More controlled studies are needed on alternative routes for opioid administration and pre-hospital pain management for potentially more frail patient subgroups. (Source: Pain and Therapy)
Source: Pain and Therapy - January 18, 2022 Category: Anesthesiology Source Type: research
Predictive Value of Contrast-Enhanced Ultrasound in Chemical Lumbar Sympathectomy for End-Stage Arteriosclerosis Obliterans of the Lower Extremities
ConclusionsPreoperative TTP response was able to predict the therapeutic effect of CLS to a certain extent, and thus may aid physicians in determining the choice of CLS treatment for patients with ASO-LE.Trial RegistrationChinese Clinical Trial Registry: ChicTR1900028424 (principal investigator: Yue Wu; date of registration: 21 December 2019). (Source: Pain and Therapy)
Source: Pain and Therapy - January 15, 2022 Category: Anesthesiology Source Type: research
