Systematic Review and Meta-analysis Seem to Indicate that Cannabinoids for Chronic Primary Pain Treatment Have Limited Benefit
ConclusionCannabinoid treatment in patients with CPP had limited benefit on pain relief; however, it might improve pain with long-term administration. (Source: Pain and Therapy)
Source: Pain and Therapy - September 21, 2022 Category: Anesthesiology Source Type: research
Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review
ConclusionsThis review explores the available evidence on efficacy of neuromodulatory modalities for CPPS and contextualizes the results with information about the type of neuromodulation, lead location and waveform, pain outcomes and assessment timepoints, and reported adverse effects. (Source: Pain and Therapy)
Source: Pain and Therapy - September 15, 2022 Category: Anesthesiology Source Type: research
Emerging Approaches for the Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN): Therapeutic Potential of the C5a/C5aR Axis
AbstractChemotherapy-induced peripheral neuropathy (CIPN) is the most common neurologic complication of chemotherapy, resulting in symptoms like pain, sensory loss, and numbness in the hands and feet that cause lots of uneasiness in patients with cancer. They often suffer from pain so severe that it interrupts the treatment, thus invalidating the entire chemotherapy-based healing process, and significantly reducing their quality of life. In this paper, we underline the role of the complement system in CIPN, highlighting the relevance of the C5a fragment and its receptor C5aR1, whose activation is thought to be involved in ...
Source: Pain and Therapy - September 13, 2022 Category: Anesthesiology Source Type: research
Effect of Transcutaneous Electrical Acupoint Stimulation Combined with Transversus Abdominis Plane Block on Postoperative Recovery in Elderly Patients Undergoing Laparoscopic Gastric Cancer Surgery: A Randomized Controlled Trial
ConclusionThe combination of TEAS and TAPB ameliorated postoperative pain, improved immune and gastrointestinal function, reduced the incidence of PONV, and effectively promoted postoperative recovery in elderly patients undergoing laparoscopic gastric cancer surgery.Trial RegistrationChinese Clinical Trial Registry (ChiCTR2100042119). (Source: Pain and Therapy)
Source: Pain and Therapy - September 13, 2022 Category: Anesthesiology Source Type: research
Clinical Application of Large Channel Endoscopic Systems with Full Endoscopic Visualization Technique in Lumbar Central Spinal Stenosis: A Retrospective Cohort Study
ConclusionsCurrent research suggests that both the Endo-Surgi Plus system and iLESSYS Delta system achieved favorable high safety and clinical outcomes in ULBD for treatment of LCSS. The use of a fully visualized trephine may have increased the efficiency of the Endo-Surgi Plus system. Moreover, the Endo-Surgi Plus system may be associated with a wider decompression range and indications. (Source: Pain and Therapy)
Source: Pain and Therapy - September 3, 2022 Category: Anesthesiology Source Type: research
Food-Specific IgG4 Antibody-Guided Exclusion Diet Improves Conditions of Patients with Chronic Pain
ConclusionsA food elimination diet based on IgG4 antibody levels may be effective in reducing pain and improving quality of life in patients with chronic pain. (Source: Pain and Therapy)
Source: Pain and Therapy - July 25, 2022 Category: Anesthesiology Source Type: research
Bilateral Erector Spinae Plane Block for Quality of Recovery Following Posterior Lumbar Interbody Fusion: A Randomized Controlled Trial
ConclusionWe found that preoperative bilateral erector spinae plane blocks provided superior early quality of recovery, postoperative analgesia, and patient satisfaction scores in patients undergoing posterior lumbar interbody fusion.Trial RegistrationChinese Clinical Trial Registry, ChiCTR1900027186, 4/11/2019. (Source: Pain and Therapy)
Source: Pain and Therapy - July 25, 2022 Category: Anesthesiology Source Type: research
A Systematic Review of the Variation in Pain Catastrophizing Scale Reference Scores Based on Language Version and Country in Patients with Chronic Primary (Non-specific) Pain
ConclusionThe weighted PCS scores for people with CPP or CPP-NOS were significantly higher in Asian language versions/Asian countries than in English, European and other language versions or Western and other countries. (Source: Pain and Therapy)
Source: Pain and Therapy - July 25, 2022 Category: Anesthesiology Source Type: research
A Survey of the Incidence of Constipation in Patients with Chronic Non-cancer Pain Using Opioid Analgesics in Japan
ConclusionUse of opioid analgesics, including weak opioids, for treating chronic non-cancer musculoskeletal pain is associated with OIC. This finding highlights the need for appropriate treatment of constipation in patients with chronic non-cancer pain in Japan.Trial RegistrationUMIN000043985. (Source: Pain and Therapy)
Source: Pain and Therapy - July 25, 2022 Category: Anesthesiology Source Type: research
Commentary: Interpreting Data of Celiac Plexus Block in Patients with Pancreatic Pain: Timing, Patients, Survival
AbstractAlthough celiac plexus block (CPB) is a well known technique that has been performed for years, only in the last 30 years controlled studies, demonstrated its efficacy and safety. A historical pathway of literature regarding CPB and a critical analysis may help understand some points which remain still controversial, for a better interpretation of data. (Source: Pain and Therapy)
Source: Pain and Therapy - July 25, 2022 Category: Anesthesiology Source Type: research
Efficacy and Safety of Add-on Mirogabalin to NSAIDs in Lumbar Spinal Stenosis with Peripheral Neuropathic Pain: A Randomized, Open-Label Study
ConclusionsThe addition of mirogabalin to NSAIDs improved VAS, EQ-5D-5L, and PGIC. The main TEAEs were somnolence and dizziness. The addition of mirogabalin to NSAIDs improved peripheral neuropathic pain associated with LSS and raised no new safety concerns.Trial RegistrationJapan Registry of Clinical Trials (jRCTs021200007). (Source: Pain and Therapy)
Source: Pain and Therapy - July 20, 2022 Category: Anesthesiology Source Type: research
A Cross-Sectional Study of the Impact of Pain Severity on Absenteeism and Presenteeism Among Japanese Full-Time Workers
ConclusionsPain severity is a risk factor for absenteeism and presenteeism, even if workers have comorbid psychological stress or mental health problems. (Source: Pain and Therapy)
Source: Pain and Therapy - July 19, 2022 Category: Anesthesiology Source Type: research
Neuromodulation in Chronic Pelvic Pain: A Narrative Review
AbstractChronic primary pelvic pain syndrome (CPPPS) is a heterogeneous disease with unknown pathogenesis and a lack of distinct pathological features, which complicates diagnosis and therapy and has a significant impact on patients' daily life. Because pharmacological management is ineffective and long-term use may result in additional system damage, developing a more effective treatment is critical. Neuromodulation has advanced rapidly over the last few decades, and various types of neuromodulations have demonstrated efficacy in the treatment of CPPPS. In this article we discuss the evolution of neuromodulation technolog...
Source: Pain and Therapy - July 14, 2022 Category: Anesthesiology Source Type: research
Long-Term Follow-Up Safety and Effectiveness of CT-Guided Radiofrequency Thermocoagulation of Sphenopalatine Ganglion in Refractory Headache Treatment
ConclusionCT-guided RFTA of the SPG significantly relieves headache symptoms in patients with refractory migraine and CH. It has the advantages of rapid onset, long duration, and a safe and reliable treatment process, making it worthy of clinical application. (Source: Pain and Therapy)
Source: Pain and Therapy - July 6, 2022 Category: Anesthesiology Source Type: research
Comparison of Patient-Controlled Caudal Epidural Analgesia and Patient-Controlled Intravenous Analgesia After Perianal Surgery: A Randomized Controlled Trial
ConclusionIn the postoperative analgesia program of perianal surgery, PCCA may provide a better analgesic effect without increasing the incidence of complications.Trial RegistrationChinese Clinical Trial Registry identifier, ChiCTR2000038425, September 2020, retrospectively registered. (Source: Pain and Therapy)
Source: Pain and Therapy - July 6, 2022 Category: Anesthesiology Source Type: research
