Application of Ultrasound-Guided Transversus Abdominis Plane Block Combined with Nalbuphine Patient-Controlled Intravenous Analgesia in Postoperative Analgesia After Laparotomy: A Randomized Controlled Trial
ConclusionsSufentanil PCIA and nalbuphine PCIA have equivalent analgesic effects, while TAPB combined with nalbuphine PCIA can ensure a good analgesic effect, thereby reducing the incidence of adverse reactions. (Source: Pain and Therapy)
Source: Pain and Therapy - April 14, 2022 Category: Anesthesiology Source Type: research
Opioids in the Elderly Patients with Cognitive Impairment: A Narrative Review
ConclusionsOpioid prescription in the elderly population with cognitive impairment is particularly complex. All healthcare professionals involved in the care of such patients need to be aware of the challenges and strive to ensure analgesic use is guided by appropriate and accurate pain assessment. (Source: Pain and Therapy)
Source: Pain and Therapy - April 5, 2022 Category: Anesthesiology Source Type: research
Migraine Outcome Should Not Be Used to Determine Diagnosis, Severity, and Therapy: Moving Towards a Multiparametric Definition of Chronicity
AbstractChronic migraine (CM) diagnosis is nowadays based on the threshold of 15 headache days/month for three consecutive months, of which at least eight have migraine headache features. In recent years, proposals for reducing the threshold to 8 days/month have been proposed. The sole frequency parameter, however, is partial considering the variability in frequency, pain severity, associated symptoms, such as nausea, osmophobia, and photophobia, and presence of aura, but also the variable response to treatment and the association with sev eral comorbidities. Therefore, in our opinion, a multiparameter perspective has to...
Source: Pain and Therapy - March 29, 2022 Category: Anesthesiology Source Type: research
EEG Recordings as Biomarkers of Pain Perception: Where Do We Stand and Where to Go?
ConclusionAlthough no robust EEG biomarkers of pain perception have been identified yet, EEG has potential and future research should be attempted. Designing strong research protocols, controlling for potential risk of biases, as well as investigating brain networks rather than isolated cortical changes will be crucial in this attempt. (Source: Pain and Therapy)
Source: Pain and Therapy - March 23, 2022 Category: Anesthesiology Source Type: research
Analgesic Efficacy of Transverse Abdominis Plane Block and Quadratus Lumborum Block in Laparoscopic Sleeve Gastrectomy: A Randomized Double-Blinded Clinical Trial
ConclusionsUltrasound-guided transversus abdominis plane block and quadratus lumborum block could provide comparable analgesic effects for a laparoscopic sleeve gastrectomy in obese patients.Trial RegistrationChinese Clinical Trial Registry; ChiCTR1800019236. (Source: Pain and Therapy)
Source: Pain and Therapy - March 21, 2022 Category: Anesthesiology Source Type: research
Comparison the Effect of Pain Neuroscience and Pain Biomechanics Education on Neck Pain and Fear of Movement in Patients with Chronic Nonspecific Neck Pain During the COVID-19 Pandemic
ConclusionIn our study population PNE did not affect the pain index, leading to the conclusion that PNE should not be used as the only treatment, but possibly in combination with other active/passive therapy to enhance the results for patients with nonspecific chronic neck pain. Moreover, online treatment may help clinicians to increase their interaction with patients during COVID-19 lockdown. (Source: Pain and Therapy)
Source: Pain and Therapy - March 21, 2022 Category: Anesthesiology Source Type: research
Determining the Definitive Time Criterion for Postherpetic Neuralgia Using Infrared Thermographic Imaging
ConclusionsThe transition of skin temperature from warm to cold occurs 12 weeks after HZ onset, which implies the end of local inflammation. Therefore, PHN associated with pathophysiologic change may be defined as 12 weeks after the skin rash. This finding provides a theoretical basis for the timing definition of PHN. (Source: Pain and Therapy)
Source: Pain and Therapy - March 14, 2022 Category: Anesthesiology Source Type: research
Letter to the Editor Regarding: “Neurophysiological Assessments During Continuous Sedation Until Death Put Validity of Observational Assessments Into Question: A Prospective Observational Study”
(Source: Pain and Therapy)
Source: Pain and Therapy - March 12, 2022 Category: Anesthesiology Source Type: research
A Response to: Letter to the Editor Regarding “Neurophysiological Assessments During Continuous Sedation Until Death Put Validity of Observational Assessments Into Question: A Prospective Observational Study”
(Source: Pain and Therapy)
Source: Pain and Therapy - March 12, 2022 Category: Anesthesiology Source Type: research
The Intraoperative Adherence to Multimodal Analgesia of Anesthesiologists: A Retrospective Study
ConclusionsAlthough anesthesiologists used more analgesics after promoting MMA, the “opioid-sparing” principle was not followed properly. The analgesic mode was not instructed by patients’ characteristics appropriately. In addition, surgeries with cumbersome preparation/process impeded the use of multiple analgesic modes, while senior anesthesiologists preferred multiple anal gesic modes. (Source: Pain and Therapy)
Source: Pain and Therapy - March 11, 2022 Category: Anesthesiology Source Type: research
Prospective Association Between Inflammatory Markers and Knee Cartilage Volume Loss and Pain Trajectory
ConclusionsIL-6 was independently associated with compartment-specific CV loss and worse pain trajectory, but the other markers studied were not, suggesting that components of inflammation are implicated in the pathogenesis of cartilage loss and developing a worse pain course. (Source: Pain and Therapy)
Source: Pain and Therapy - February 22, 2022 Category: Anesthesiology Source Type: research
Comparison of Analgesic Effects between Nalbuphine and Sufentanil in First-Trimester Surgical Abortion: A Randomized, Double-Blind, Controlled Trial
ConclusionsNalbuphine combined with propofol is superior to sufentanil combined with propofol for first-trimester abortion surgeries.Clinical Trial RegistrationThe trial was registered atwww.chictr.org.cn, identifier ChiCTR2000040243. (Source: Pain and Therapy)
Source: Pain and Therapy - February 22, 2022 Category: Anesthesiology Source Type: research
Comparative Benefit –Risk Assessment for Lidocaine 700 mg Medicated Plaster and Pregabalin in Peripheral Neuropathic Pain Following a Structured Framework Approach
ConclusionGuided by the opinion of patients regarding key benefits and risks deemed important for treatments of peripheral neuropathic pain, our analysis showed that lidocaine 700 mg medicated plaster has a more favorable benefit–risk balance compared to pregabalin (300 and 600 mg daily). (Source: Pain and Therapy)
Source: Pain and Therapy - February 22, 2022 Category: Anesthesiology Source Type: research
Improved Treatment Effect of Triamcinolone Acetonide Extended-Release in Patients with Concordant Baseline Pain Scores on the Average Daily Pain and Western Ontario and McMaster Universities Osteoarthritis Index Pain Scales
ConclusionsIn patients reporting moderate-to-severe knee OA pain at baseline based on concordant ADP and WOMAC-A scores, TA-ER provided statistically significant pain relief for ≥ 12 weeks compared with conventional TAcs.Trial RegistrationClinicalTrials.gov Identifier: NCT02357459. (Source: Pain and Therapy)
Source: Pain and Therapy - February 22, 2022 Category: Anesthesiology Source Type: research
Letter to the Editor Regarding: The Effect of Preoperative Anxiety and Pain Sensitivity on Preoperative Hemodynamics, Propofol Consumption, and Postoperative Recovery and Pain in Endoscopic Ultrasonography
(Source: Pain and Therapy)
Source: Pain and Therapy - February 22, 2022 Category: Anesthesiology Source Type: research
