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Types of DNA damage and research progress
Nucleosides Nucleotides Nucleic Acids. 2023 Nov 10:1-21. doi: 10.1080/15257770.2023.2277194. Online ahead of print.ABSTRACTDNA damage is a modification in the structure of DNA under the influence of endogenous or exogenous factors. DNA damage can cause different types of diseases and is closely related to genetic mutations, cancer, and aging. The cause of the corresponding reaction process is essential for the study of related cancers and other genetically related diseases. Therefore, it is essential to gain a deeper understanding of the various types of DNA damage. This paper provides a comprehensive review of recent adva...
Source: Nucleosides, Nucleotides and Nucleic Acids - November 10, 2023 Category: Biochemistry Authors: Liu Nian Li Xiaohua Li Rongcheng Liu Song-Bai Source Type: research

Clinical use of biomarkers in the field of cytotoxic nucleoside analogues
CONCLUSION: There is still much to do in the field of outcome-prediction with nucleoside analogues. The use of multiparametric methods could increase the success rate but at the cost of a poorer understanding of molecular mechanisms.PMID:37874211 | DOI:10.1080/15257770.2023.2272640 (Source: Nucleosides, Nucleotides and Nucleic Acids)
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Lars Petter Jordheim Source Type: research

Looking for the unexpected in purine and pyrimidine metabolism
Nucleosides Nucleotides Nucleic Acids. 2023 Oct 24:1-9. doi: 10.1080/15257770.2023.2272647. Online ahead of print.ABSTRACTIn June 2023, the Purine and Pyrimidine Society (PPS) organized the 20th biennial symposium on Purine and Pyrimidine metabolism (PP23). The symposium was organized in Los Angeles, California, USA, by Pr Caius Radu affiliated to UCLA. The scientific program covered various topics such as inborn errors, cancer, immunity, enzymatic reactions, drug development etc and was presented at 9 sessions over three days. The current issue of Nucleosides, Nucleotides & Nucleic Acids is a special issue covering pr...
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Lars Petter Jordheim Caius G Radu Godefridus J Peters Source Type: research

Association between interferon-gamma ( < em > IFN- γ < /em > ) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis
In conclusion, this meta-analysis suggests that two SNPs in IFN-γ may be associated with TB susceptibility in non-Asian populations. However, for Asians, there is no evidence to support a conclusive relationship between these SNPs and the risk of TB.PMID:37874649 | DOI:10.1080/15257770.2023.2272641 (Source: Nucleosides, Nucleotides and Nucleic Acids)
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Xu Hu Xiaoying Lu Source Type: research

Clinical use of biomarkers in the field of cytotoxic nucleoside analogues
CONCLUSION: There is still much to do in the field of outcome-prediction with nucleoside analogues. The use of multiparametric methods could increase the success rate but at the cost of a poorer understanding of molecular mechanisms.PMID:37874211 | DOI:10.1080/15257770.2023.2272640 (Source: Nucleosides, Nucleotides and Nucleic Acids)
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Lars Petter Jordheim Source Type: research

Looking for the unexpected in purine and pyrimidine metabolism
Nucleosides Nucleotides Nucleic Acids. 2023 Oct 24:1-9. doi: 10.1080/15257770.2023.2272647. Online ahead of print.ABSTRACTIn June 2023, the Purine and Pyrimidine Society (PPS) organized the 20th biennial symposium on Purine and Pyrimidine metabolism (PP23). The symposium was organized in Los Angeles, California, USA, by Pr Caius Radu affiliated to UCLA. The scientific program covered various topics such as inborn errors, cancer, immunity, enzymatic reactions, drug development etc and was presented at 9 sessions over three days. The current issue of Nucleosides, Nucleotides & Nucleic Acids is a special issue covering pr...
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Lars Petter Jordheim Caius G Radu Godefridus J Peters Source Type: research

Association between interferon-gamma ( < em > IFN- γ < /em > ) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis
In conclusion, this meta-analysis suggests that two SNPs in IFN-γ may be associated with TB susceptibility in non-Asian populations. However, for Asians, there is no evidence to support a conclusive relationship between these SNPs and the risk of TB.PMID:37874649 | DOI:10.1080/15257770.2023.2272641 (Source: Nucleosides, Nucleotides and Nucleic Acids)
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Xu Hu Xiaoying Lu Source Type: research

Clinical use of biomarkers in the field of cytotoxic nucleoside analogues
CONCLUSION: There is still much to do in the field of outcome-prediction with nucleoside analogues. The use of multiparametric methods could increase the success rate but at the cost of a poorer understanding of molecular mechanisms.PMID:37874211 | DOI:10.1080/15257770.2023.2272640 (Source: Nucleosides, Nucleotides and Nucleic Acids)
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Lars Petter Jordheim Source Type: research

Looking for the unexpected in purine and pyrimidine metabolism
Nucleosides Nucleotides Nucleic Acids. 2023 Oct 24:1-9. doi: 10.1080/15257770.2023.2272647. Online ahead of print.ABSTRACTIn June 2023, the Purine and Pyrimidine Society (PPS) organized the 20th biennial symposium on Purine and Pyrimidine metabolism (PP23). The symposium was organized in Los Angeles, California, USA, by Pr Caius Radu affiliated to UCLA. The scientific program covered various topics such as inborn errors, cancer, immunity, enzymatic reactions, drug development etc and was presented at 9 sessions over three days. The current issue of Nucleosides, Nucleotides & Nucleic Acids is a special issue covering pr...
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Lars Petter Jordheim Caius G Radu Godefridus J Peters Source Type: research

Association between interferon-gamma ( < em > IFN- γ < /em > ) gene polymorphisms and tuberculosis susceptibility: a systematic review and meta-analysis
In conclusion, this meta-analysis suggests that two SNPs in IFN-γ may be associated with TB susceptibility in non-Asian populations. However, for Asians, there is no evidence to support a conclusive relationship between these SNPs and the risk of TB.PMID:37874649 | DOI:10.1080/15257770.2023.2272641 (Source: Nucleosides, Nucleotides and Nucleic Acids)
Source: Nucleosides, Nucleotides and Nucleic Acids - October 24, 2023 Category: Biochemistry Authors: Xu Hu Xiaoying Lu Source Type: research