Mediterranean Journal of Hematology and Infectious Diseases Mediterranean Journal of Hematology and Infectious Diseases RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The systemic mastocytosis: radiological point of view
Radiological diagnosis of systemic mastocytosis (SM) can be hard to establish. This is mainly due to the variable radiological features involving many organ systems (e.g., respiratory, cardiovascular, lympho-reticular, digestive systems, and most commonly skin), and the broad spectrum of skeletal findings, in particular. Skeletal involvement is the most common and prominent imaging feature in patients with SM and represents a prognostic factor as it may entail an aggressive course of the disease. Diagnosis, which is largely established by histological evaluation of a bone marrow trephine biopsy specimen supplemented by ima...
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 28, 2021 Category: Hematology Authors: ANTONIO LEONE, SILVIA MACAGNINO, GIULIA D ' AMBRA, DANIELE PERLA Source Type: research

High-risk sexual behaviours among vulnerable women in northern uganda, baseline results from pe atye kena cohort study
Conclusions: In this cohort, HIV prevalence is high and sexual high-risk behaviors are multifaced; future interventions will be aimed to reduce HIV/STIs misconceptions and to promote a sense of community, self-determination and female empowerment. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 28, 2021 Category: Hematology Authors: Francesco Vladimiro Segala, Giulia Micheli, Cristina Seguiti, Andrea Pierantozzi, Robert Lukwiya, Benson Odong, Francesco Aloi, Emmanuel Ochola, Roberto Cauda, Katleen De gaetano Donati, Antonella Cingolani Source Type: research

Glucose metabolism and insulin response to oral glucose tolerance test (ogtt) in prepubertal patients with transfusion dependent Β-thalassemia (tdt): a long-term retrospective analysis
Conclusion:This study shows a spectrum of disturbances in glucose homeostasis among TDT patients and that prepubertal patients with IFG are at higher risk for developing a deterioration of glucose metabolism.  (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 28, 2021 Category: Hematology Authors: Vincenzo De Sanctis, Ashraf Soliman, Ploutarchos Tzoulis, Shahina Daar, Salvatore Di Maio, Bernadette Fiscina, Christos Kattamis Source Type: research

I increased risk of lymphoma in men infected with tuberculosis
Conclusion: A high proportion of Mycobacterium tuberculosis infection was found in patients with lymphoma. In TB-infected patients, older age and male gender are associated with susceptibility to lymphoma, suggesting the awareness of a screening program might be useful for early detection of lymphoma. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 28, 2021 Category: Hematology Authors: guangliang Chen Source Type: research

Treatment of relapsed/refractory CLL with Venetoclax-Rituximab during the COVID-19 pandemic: A daily-life experience in southern Italy.
With more than 3 million proven infections and 100.000 associated deaths in Italy, the COVID-19 pandemic poses extraordinary challenges to health-care professionals and especially to those caring for patients with haematologic malignancies (1-2). Given the multiple   immune defects characterizing chronic lymphocytic leukaemia (CLL), it is considered that patients with this form of leukemia have a high-risk of suffering severe forms of COVID-19 (3-4). (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Stefano Molica, Paolo Sportoletti, Nicola Di Renzo, Pellegrino Musto, Fabrizio Pane, Francesco Di Raimondo Source Type: research

Systemic mastocytosis: molecular landscape and implications for treatment
Over the past decade we have witnessed major advances in the molecular characterization of systemic mastocytosis (SM). This has provided important information for a better understanding of the pathogenesis of the disease but has also practically impacted on the way we diagnose and manage it. Advances in molecular testing has indeed run in parallel with advances in therapeutic targeting of constitutive active KIT, the major driver of the disease. Assessing the molecular landscape in each individual SM patient is nowadays important for diagnosis, prognosis, treatment and monitoring of therapeutic efficacy. This is facilitate...
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Cecilia Monaldi, Sara De Santis, Manuela Mancini, Samantha Bruno, Michele Cavo, Simona Soverini Source Type: research

The prothrombotic state associated with sars-cov-2 infection: pathophysiological aspects
Severe coronavirus disease-2019 (COVID-19) is frequently associated with microvascular thrombosis, especially in the lung, or macrovascular thrombosis, mainly venous thromboembolism, that significantly contribute to the mortality burden of the disease. COVID-19 patients also exhibit distinctive laboratory abnormalities that are compatible with a prothrombotic state. The key event underlying COVID-19-associated thrombotic complications is an excessive host inflammatory response to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection generating multiple inflammatory mediators, mainly cytokines and complemen...
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Nicola Semeraro, Prof. Mario Colucci Source Type: research

Crocin promotes apoptosis in human ebv-transformed b-lymphocyte via intrinsic pathway
Conclusion: The results suggest that crocin may serve as a good alternative/coadjuvant to vincristine in EBV-associated B-cell lymphoproliferative disorders.Keywords: Crocin, CO 88BV59-1 cells, EBV-associated B-cell lymphoproliferative disorders, apoptosis (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Abdolreza Sotoodeh Jahromi, Mohammad Kargar, Farshid Kafilzadeh, Marzieh Jamalidoust, Maliheh Moradzadeh Source Type: research

Hsa-miR-5581-3p and hsa-miR-542-3p target the F8 gene in hemophilia A without F8 mutations
Conclusion:Hsa-miR-5581-3p and hsa-miR-542-3p target the F8 gene and suppress the expression of FVIII protein, which may contribute to the development of HA without F8 mutations. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Feiying Meng Source Type: research

A a retrospective long-term study on age at menarche and menstrual characteristics in 85 young women with transfusion-dependent Β-thalassemia (tdt) born between 1965 and 1995
Conclusion: An early ICT in TDT patientswas associated to a normal " tempo " of pubertal onset and to a higher frequency of subsequent regular menstrual cycles. In TDT patients, who developed SA, a diagnosis of acquired central hypogonadism was made, mainly due to the chronic exposure to iron overload, however other potential causes linked to nutritional status,deficient levels of circulating nutrientsandthe chronic disease itself cannot be excluded.  (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Vincenzo De Sanctis, Salvatore Di Maio Source Type: research

Invasive fungal infection in children with acute leukemia and severe aplastic anemia
Although the outcome of childhood leukemia and severe aplastic anemia (SAA) has improved, infectious complications are still the major concern, particularly invasive fungal infection (IFI), which is one of the most common causes of infectious related death in such patients with prolonged neutropenia.  A retrospective study of IFI in pediatric patients with newly diagnosed and relapsed acute leukemia and SAA in Siriraj Hospital, Mahidol University, Thailand, was conducted.   There were 241 patients (150 patients with ALL, 35 patients with AML, 31 patients with relapsed leukemia and 25 patients with SAA) with ...
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Sutatta Supatharawanich, Nattee Narkbunnam, Nassawee Vathana, Chayamon Takpradit, Kamon Phuakpet, Bunchoo Pongtanakul, Sasima Tongsai, Phakatip Sinlapamongkolkul, Popchai Ngamskulrungroj, Wanatpreeya Phongsamart, Kleebsabai Sanpakit , Jassada Source Type: research

Ibrutinib associated cardiovascular events in a patient wearing an implanted loop recorder
Ibrutinib is a well-tolerated and effective therapy used for the treatment of chronic lymphocytic leukemia (CLL). Its use has been associated with cardiovascular events such as atrial fibrillation (Afib), hypertension, and ventricular arrhythmias. Implanted loop recorders are a useful tool in guiding the management of patients with cardiac arrhythmias. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Daniel Rivera, Koichi Takahashi, Jean-Benard Durand, Alessandra Ferrajoli Source Type: research

Aberrant acquisition of T-cell associated markers in plasma cell neoplasms: An aggressive disease with extramedullary involvement and very short survival
Conclusion:Due to rarity of this aberrant phenotype and scarcity of the published data, the precise causative mechanism and its clinical implications have not yet been elucidated. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Dina Sameh Soliman, Hesham Elsabah, Ibrahim Ganwo, Aliaa Amer, Ruba Y Taha, Lajos Szabados , Mouhammad Sharaf Eldean, Ahmad Al-Sabbagh, Feryal Ibrahim Source Type: research

A rare case of superior ophthalmic vein thrombosis and thrombocytopenia following ChAdOx1 nCoV-19 vaccine against SARS-CoV-2
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Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Irina Panovska-Stavridis Source Type: research

Immune thrombocytopenic purpura cases following COVID-19 vaccination.
Not requested. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 28, 2021 Category: Hematology Authors: Annalisa Condorelli, Uros Markovic, Roberta Sciortino, Mary Ann Di Giorgio, Daniela Nicolosi, Gaetano Giuffrida Source Type: research