Mediterranean Journal of Hematology and Infectious Diseases This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The clinical significance of the spectrum of interactions of the rare ivs-ii-5 g > c (hbb: c.315+5 g > c) variation with other Β-thalassemia mutations in southern china
Conclusion:Compound heterozygotes for IVS-II-5 G>C and other severe β-thalassemia mutations are phenotypically severe enough to necessitate appropriate therapy and counseling. Co-inheritance of this nucleotide substitution with other β-thalassemia mutations may account for a considerable portion of the incidence of undiagnosed patients with TI and TM in Guangxi. T he IVS-II-5 G>C mutation can pose serious difficulties in screening and counseling.Keywords: β-thalassemia; IVS-II-5 G>C; genotype; phenotype (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Yali Zhou, Guiping Liao, Xiaolin Yin, Sheng He, Yi Wu, Jian Xiao, Zhili Geng, Qiuying Huang, Ganghui Luo, Kun Yang Source Type: research

Endothelial biomarkers in patients recovered from covid-19 one year after hospital discharge: a cross-sectional study
Conclusions: SARS-CoV-2 infection may not impose a higher risk of long-term cardiovascular sequelae, even for those recovered from severe illness.KEYWORDS: COVID, ENDOTHELIAL DYSFUNCTION, INFLAMMATORY MARKERS, ADHESION MOLECULES, THROMBOSIS. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Ming Tong, Xiquan Yan, Yu Jiang, Zhaoxia Jin, Shengjiao Zhu, Lianhong Zou, Yanjuan Liu, Qing Zheng, Guoqiang Chen, Ruifeng Gui Gui, Zhilan Zhou, Xiaotong Han, Jiangming He, Siqing Yin, Changchun Ma, Wen Xiao, Yong Zeng, Fang Chen, Yimin Zh Source Type: research

Comparison of empiric antibiotic escalation therapy with vancomycin (van) versus linezolid (lin) in patients with febrile neutropenia
Conclusion:The antibiotic therapy in febrile neutropenia with LIN showed a trend to a better efficacy than therapy with VAN. But because of the small sample size and the retrospective manner VAN may still be considered a reasonable option in neutropenic fever and randomized studies are needed in this field.KEYWORDS: GRAM+ INFECTIONS, VANCOMYCIN, LINEZOLID, DOSE ESCALATION. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Karin Mayer, Nicolaus Hegge, Ernst Molitor, Peter Brossart, Corinna Hahn-Ast Source Type: research

The Mediterranean Journal of Hematology and Infectious Diseases: A New Milestone and a Hope for Researchers in Third World Countries
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Nawfal R Hussein Source Type: research

Post-therapy B regulatory cells might early predict relapse in Hodgkin lymphoma
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Valentina Giudice, Luca Pezzullo, Giuseppe Ciancia, Matteo D ' Addona, Francesca D ' Alto, Marisa Gorrese, Bianca Cuffa, Carmine Selleri Source Type: research

Ixazomib-associated skin exfoliation
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Yali Zhang, Long Zhao, Yuancheng Guo, bei liu Source Type: research

Managment of Relapsed/Refractory ALL With Inotuzumab During COVID-19. A Casr Report
We describe the clinical history of a 40-year-old male with relapsed B-common ALL who developed Sars-CoV2 prior to treatment initiation with inotuzumab. Since the patient was asymptomatic for COVID-19, the first dose of inotuzumab was administered, followed by remdesivir as prophylaxis. However, a worsening in respiratory findings led to a delay in administering the following doses of inotuzumab. Interestingly, even if the patient did not receive the full inotuzumab cycle, he achieved a complete hematologic remission: furthermore, he spontaneously developed anti-sars-COV2 antibodies. COVID-19 treatment also included conval...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Martina Di Palma, Elio Gentilini, Chiara Masucci, Alessandra Micozzi, Ombretta Turriziani, Antonino Mul è, Robin Foà, Maurizio Martelli, Gabriella D ' Ettorre, Saveria Capria, Sabina Chiaretti Source Type: research

TDT Positive High-Grade Lymphoma with Myc, BCL2 And BCL6 Rearrangements: a Review of Diagnosis and Treatment
In the modern era, classification of neoplasms not only depends on immunomorphological features but also on specific disease defining genetic events. Translocations/rearrangements of MYC/8q24 locus in combination with BCL-2 or BCL6 translocations (double/triple hit) are considered hallmarks of high-grade B-cell lymphoma (HGBL), a type of aggressive mature B-cell lymphoma. When cases with immature immunophenotype present with these rearrangements, establishment of diagnosis becomes very difficult. We herein report an unusual case of B-cell lymphoma that presented with immature morphology and immunophenotype with triple hit ...
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Aditi Singh, MD, Ishaq Asghar, MD, Laura Kohler, DO, Hosam Hakim, MD, Daniel Snower, MD, Daniel Lebovic, MD Source Type: research

The treatment of advanced-stage mycosis fungoides and sezary syndrome: a hematologist's point of view.
Cutaneous T-cell lymphomas are a heterogenous group of T-cell neoplasms involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or S ézary Syndrome (SS).Mycosis fungoides (MF) is usually associated with an indolent clinical course and intermittent, stable, or slow progression of the lesions. Extracutaneous involvement (lymph nodes, blood, or less commonly other organs) or large cell transformation (LCT) may be seen in advanced-stage disease. Sezary syndrome (SS) is a rare leukemic subtype of CTCL characterized by significant blood involvement, erythroderma, and often lymphadenopathy.Although ...
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Antonio Giordano, Livio Pagano Source Type: research

Classic kshv/hhv-8-positive primary effusion lymphoma (pel): a systematic review and meta-analysis of case reports
Primary effusion lymphoma (PEL) is a large B-cell lymphoma growing within body-cavities caused by the Kaposi sarcoma-associated herpesvirus (KSHV)/human herpesvirus-8 (KSHV/HHV-8). It is mainly reported in HIV-infected patients. The uncommon occurrence in the elderly supports a form paralleling classic Kaposi sarcoma (KS), i.e. classic PEL, whose characteristics are relatively underexplored. To better understand the diagnostic modalities and clinical-epidemiological features of classic PEL, articles reporting cases of PEL were identified through MEDLINE/EMBASE databases (January 1998-July 2020) and screened according to PR...
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Ilaria Cozzi, Giovanni Rossi, Emma Rullo, Valeria Ascoli Source Type: research

The dark side of the covid-19 treatments on mycobacterium tuberculosis infection
Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) at the end of 2019, a number of medications have been used to treat the infection and the related Coronavirus disease – 19 (COVID-19).Some of the administered drugs were tested or used in practice only on the basis of biological plausibility; a promising strategy was to target the host immune response, with host directed therapies (HDTs), to reduce systemic hyperinflammation and hypercytokinemia responsible for additional tissue damage.We summarize the treatments against SARS-CoV-2 and underline their possible effects onMycobacterium tube...
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Flavio De Maio, Delia Mercedes Bianco, Giovanni Delogu Source Type: research

CAR-T cells microscopic and phenotypic identification in the peripheral blood
CAR-T cells are a new possibility for care poor prognostic conditions. CAR-T cells injection lead to T chimeric cells circulation into the blood. Here is reported the cytomorphologic and immunophenotypic features of CAR-T cells in the peripheral blood. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: LESESVE Source Type: research

A Suspected Case of Cerebral Fat Embolism Triggering a Drug-resistant Status Epilepticus in a HbS/ β⁺-Thalassaemia Patient
Sickle cell disease (SCD) refers to a group of hereditary disorders associated with clinical manifestations of variable severity. C In particular, Fat Embolism Syndrome, a rare and devastating complication of SCD, may preferentially involve non-homozygous patients and patients with mild disease. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Marta Bortolotti, Gianluca Costamagna, Marta Mancarella, Delia Gagliardi, Silvia Lanfranconi, Alessia Marcon, Margherita Migone De Amicis, Nereo Bresolin, Stefania Corti, Giovanna Graziadei Source Type: research

Intracardiac thrombosis in the three-year-old boy with normal left ventricle systolic function in MIS-C associated with COVID-19
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Stasa Krasic, Sasa Popovic, Ruzica Kravljanac, Sergej Prijic, Vladislav Vukomanovic Source Type: research

Challenging management of severe differentiation syndrome in pediatric acute promyelocytic leukemia treated with ATRA/ATO
The ATRA/ATO combination treatment of acute promyelocytic leukemia (APL) represents a paradigm of successful targeted and chemotherapy-free treatment in oncology. This therapeutic strategy is aimed at sparing patients from chemotherapy toxicity, while maintaining an excellent survival with a low risk of relapse. Main induction treatment-related complications are differentiation syndrome (DS) and hyperleukocytosis, which is related to DS and its severity. In the period December 2019 – December 2020, 8 children with newly diagnosed APL underwent induction therapy with ATRA/ATO in our center. In patients with WBC≥10x109/L...
Source: Mediterranean Journal of Hematology and Infectious Diseases - February 27, 2022 Category: Hematology Authors: Alessandro Molinaro, Daniela Zanta, Maria Luisa Moleti, Fiorina Giona, Valentino Conter, Carmelo Rizzari, Andrea Biondi, Anna Maria Testi Source Type: research