Comparative analysis of clinical and laboratory data in children with multisystem inflammatory syndrome associated with sars-cov-2 in the republic of kazakhstan
Conclusions: MIS-C is a severe, life-threatening systemic disease characterized by multiple organ damage and important inflammatory changes in laboratory parameters. A more aggressive clinical course of MIS-C in 2021 may be associated with the emergence of new SARS-CoV-2 strains.Keywords: children, MIS-C, variants of SARS-CoV-2 (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Indira Jaxybayeva, Riza Boranbayeva, Sagira Abdrakhmanova, Raikhan Maitbassova, Pakhitkanym Ishuova, Dinagul Bayesheva, Nurila Maltabarova, Adyl Katarbayev, Kumisgul Umesheva, Tatyana Marshalkina, Lyazat Manzhuova, Gulnara Abdilova1, Gulshat A Source Type: research

Clinical manifestations, imaging features, and treatment follow-up of 29 cases with hepatic tuberculosis
To understand the clinical and imaging manifestations and the treatment and follow-up of hepatic tuberculosis (HTB), we retrospectively analyzed the clinical and imaging data of 29 patients with HTB who had been diagnosed clinically or by biopsy, and the clinical and imaging data had been summarised. Patient characteristics were followed up after anti-TB drug treatment. The median age of the 29 patients with HTB was 37 years, and most were male (58.6%). The patient ' s symptoms included fever (48.2%), respiratory symptoms (27.5%), abdominal pain (24.1%), and abdominal distension (10.3%). Elevated erythrocyte sedimentation ...
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Saiduo; Wei, Jichan, Xinchun, Hongye, Ning, Xiangao Jiang Source Type: research

Circrna circehbp1 regulates the maturation of mir-129 to increase the chemoresistance of cancer cells to adriamycin in acute myeloid leukaemia
Conclusion:Therefore, circEHBP1 may suppress the maturation of miR-129 to increase the chemoresistance of cancer cells to ADR in AML.Keywords:acute myeloid leukaemia, circEHBP1, miR-129, adriamycin (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Hong Li, Kehong Bi, Saran Feng, Yan Wang, Chuansheng Zhu Source Type: research

Acquired Sideroblastic Anemia: An exploratory Comparative Statistical Analysis Between Clonal and Non-clonal cases
Sideroblastic anemia (SA) is a rare heterogenous group of inherited and acquired bone marrow disorders. We retrospectively studied the clinicopathologic characteristics, cytogenetic findings, and disease outcome of patients with acquired sideroblastic anemia (ASA) and performed a comparative analysis between clonal and non-clonal cases. 15 patients of ASA were detected: clonal SA (10 cases, 66.7%) including MDS, MDS/MPN, AML and t-MNs with ring sideroblasts) and SA secondary to non-clonal causes (5 cases; 33.3%), including copper deficiency (2 sideroblastic anemia, copper deficiency, non-clonal sideroblastic anemia cases),...
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Dina Sameh Soliman, Samah Kohla, Shehab Fareed, Susanna Akiki , Aliaa Amer, Ibrahim Ganwo, Prem Chandra, Halima El-Omri, Feryal Ibrahim Source Type: research

Molecular characteristics of hepatitis B virus in children of Huzhou area, China
Conclusion: The predominant genotype and serotype were B and adw among children in Huzhou. Genotype B, MHR mutations, and low anti-HBs levels might be related to immunization failure, although the large-scare vaccination program remarkably decreased the infection of HBV in children, strengthen immunization is recommend in children with low level anti-HBs. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Fang Jin, Fuchu Qian, Dongli Li, Chenxin Yan, Weihua Zou Source Type: research

Clonal hematopoiesis: role in hematologic non-hematologic
Hematopoietic stem cells (HSCs) ensure the coordinated and balanced production of all hematopoietic cell types throughout life. Aging is associated with a gradual decline of the self-renewal and regenerative potential of HSCs and with the development of clonal hematopoiesis. Clonal hematopoiesis of indeterminate potential (CHIP) is a term defining the clonal expansion of genetically variant hematopoietic cells bearing one or more gene mutations and/or structural variants (such as copy number alterations). CHIP increases exponentially with age and is associated with cancers, including hematologic neoplasia, cardiovascu...
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Ugo Testa, Dr. Germana Castelli, Dr. Elvira Pelosi Source Type: research

Comparison of the clinical and laboratory features of covid and influenza in children
Conclusions. There are no symptoms characteristic of a single infectious agent, with flu-like disorders being the most common. In addition, laboratory tests do not help in the differential diagnosis but show a limited inflammatory response in COVID-19. This could explain the fewer complications compared to adulthood, with a less severe clinical course.Keywords: COVID-19; Influenza; children (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Davide Pata, Danilo Buonsenso, Piero Valentini Source Type: research

Bacillus cereus in the neutropenic patient: case report in a patient with myelodysplastic syndrome and review of the literature
Bacillus cereus is aGram-positive rod that can cause foodintoxication, localized infection, orbacteremia with potential organ involvement (e.g.,meningitis, cerebral and liver abscesses, pneumonia, etc.). Patients with neutropenia and/or hematological diseases are at greater risk for invasiveB. cereus infections. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Mariam Markouli, Sevastianos Chatzidavid, Dimitra Vlachopoulou, Nefeli Giannakopoulou, Amalia Anastasopoulou, Nora-Athina Viniou, Panagiotis Diamantopoulos Source Type: research

Congenital Atypical Microcytic Anemia Accompanied by Iron Deficiency and Accumulation
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: mustafa özay, zafer bıçakçı Source Type: research

Utility of flow cytometry ascitic fluid analysis for rapid diagnosis of B-cell peritoneal lymphomatosis
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - August 27, 2022 Category: Hematology Authors: Maria Laura Bisegna, Niccol ò Noccioli, Irene Della Starza, Alice Di Rocco, Nadia Peragine, Maria Stefania De Propris Source Type: research

The correlation between ineffective erythropoiesis biomarkers and development of extramedullary hematopoiesis in patients with thalassemia
Conclusions:Advanced age and high PS-exposed RBC levels are associated with EMH in thalassemia. PS-exposed RBCs showed a modest correlation with EMH and may be used to predict the development of EMH in thalassemia. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Siriyakorn Chansai, Supawadee Yamsri, Supan Fucharoen, Goonnapa Fucharoen, Nattiya Teawtrakul Source Type: research

Pre and post-monoclonal infusion neutralizing activity in a subgroup of patients treated in the presence of two sars-cov-2 dominant variant of concern (vocs) and an ongoing vaccination. overall clinical efficacy of two monoclonal antibodies association in umbria
Conclusions:Alpha infections occurred prevalently in unvaccinated patients or after 5-6 months, while delta infections prevailed in vaccinated ones. A poor neutralizing activity in most of these patients was seen. A higherNAbT after infusion ofcasirivimab/imdevimab was observed. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Elisabetta Schiaroli, Giuseppe Vittorio De Socio, Anna Gidari, Lisa Malincarne, Sara Benedetti , Alessandra Lanzi, Sabrina Bastianelli, Sara Pierucci, Chiara busti, Daniela Francisci Source Type: research

Sinopharm Vaccine, SARS-CoV-2 breakthrough infections and Hemoglobinopathies
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: rujittika mungmunpuntipantip, viroj wiwanitkit Source Type: research

Nodular lymphocyte-predominant Hodgkin lymphoma in a patient with Familial Mediterranean Fever
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Marina Belia, Asimina Papanikolaou, Panagiotis Skendros, Theodoros Vassilakopoulos Source Type: research

Prospective, case-control study of serological response after two doses of BNT162b2 anti-SARS-CoV-2 mRNA vaccine in transfusion-dependent thalassemic patients
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: NICOLA SGHERZA, Stefania Zucano, Angelantonio Vitucci, Antonio Palma, Francesco Tarantini, Daniela Campanale, Luigi Vimercati, Angela Maria Vittoria Larocca, Domenico Visceglie, Amalia Acquafredda, Angelo Ostuni, Daniela Di Gennaro, Carmen Vitucci, Silvi Source Type: research