Mediterranean Journal of Hematology and Infectious Diseases This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Assessment of congenital neutropenia in children: common clinical sceneries and clues for management
A disparate group of rare hematological diseases characterized by impaired maturation of neutrophil granulocytes defines congenital neutropenias. Neutropenic patients are prone to recurrent infections beginning in the first months of life. Of interest is “cyclic neutropenia”, an ultra-rare disorder revealed by sinusoidal variations of the neutrophil count and periodically-recurring infections every 21 days. Diagnosis of these disorders is frequently obscured by the multiple causes of recurrent fevers in children. Aim of this overview is to outli ne the physical assessment of children presenting with early-ons...
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Ilaria Lazzareschi, Elena Rossi, Antonietta Curatola, Giovanna Capozio, Luca Benacquista, Ludovica Iezzi, Donato Rigante Source Type: research

VEGF and IL-6 correlation in POEMS: a potential upcoming marker of active disease and early autologous BMT response.
Conclusions:So far, to the best of our knowledge, IL-6 could be considered as a marker of active disease and reliable up to the very first months after BMT, after which its accuracy appears to be lost due to unknown factors, still to be investigated. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Luca Laurenti, Idanna Innocenti, Giulia Benintende, Annamaria Tomasso, Francesco Autore, Alberto Fresa, Florenzia Vuono, Silvia Baroni, Claudia Giannotta, Patrizia Chiusolo, Federica Sor à, Simona Sica Source Type: research

Severe immune thrombocytopenia (ITP) following SARS-CoV-2 mRNA vaccine in a girl on immunosuppressive treatment and in prolonged stable phase of ITP.
Rare cases of immune thrombocytopenia (ITP) occurring after SARS-CoV-2 mRNA vaccines have recently reached public attention. It has been reported in patients with previous ITP or other autoimmune diseases and in individuals with an apparent negative past medical history.  The management and the outcome of these cases are still not well investigated and reported in the medical literature. A 23-year-old female with a past medical history of ITP, in stable complete remission for 3 years and on mycophenolate treatment received SARS-CoV-2 mRNA vaccine. She presented severe ITP recurrence with hemorrhagic symptoms after the...
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: SIMONA BIANCHI, ALESSIA ANGI, MAURO PASSUCCI, GIOVANNA PALUMBO, ERMINIA BALDACCI, ANNA MARIA TESTI Source Type: research

Clinical and Prognostic Features in a Young Adult Patient with de novo Myelodysplastic Syndrome presenting t(11;16) (q23; q24)
This study reinforces the importance of characterizing new chromosomal alterations and their impact on prognosis in MDS. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Viviane Lamim Lovatel, Luize Otero, Ercole Pietro Orlando, Claudia Diniz, Filipe Vicente dos Santos-Bueno, Bruno Almeida Lopes, Elaiza Almeida Ant ônio de Kós, Monica Kopischitz Praxedes Lusis, Eliana Abdelhay, Teresa de Souza Fernandez Source Type: research

Coexistence of T-Large Granular Lymphocyte Leukemia and Peripheral T Cell Lymphoma-NOS with indolent behaviour
We report a case of a 68-year-old man patient who develops two different T-cell neoplasms (Large Granular Lymphocyte Leukemia [LGLL] in 2018 and Peripheral T-cell non-Hodgkin lymphoma  not otherwise specified [PTCL-NOS] in 2019) with a previous diagnosis of B-cell marginal zone lymphoma in 2010, treated with two lines of chemo-immunotherapy. The coexistence of these different T-cell neoplasms is rarely reported in literature and, moreover, is usually described as an LGLL transformation into PTCL-NOS; differently from these examples, herein the simultaneous conditions appear to be driven by different T-cell clones. Fur...
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Luca Guarnera, Valentina Boldrini, Gianmario Pasqualone, Carolina Cimino, Elisa Meddi, Roberta Laureana, Donata Trivigno, Giovanni Del Poeta, Alessandro Mauriello, Lucia Anemona, Massimiliano Postorino, Maria Cantonetti Source Type: research

Mir-140 targets lncrna dnajc3-as1 to suppress cell proliferation in acute myeloid leukemia
Conclusion ：In conclusion, miR-140 may target DNAJC3-AS1 to suppress cell proliferation in AML. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Hong Li, Kehong Bi, Saran Feng, Yan Yan Wang, Chuansheng Zhu Source Type: research

Typical and atypical presentation of covid-19 infection in children in the top of pandemic in minia governorate (two center experience)
Conclusion: COVID-19 has many clinical  classic presentation in children  however  other non-typical presentation like hematological. CNS and renal presentation has been reported.   (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Gehan Lotfy Abdel Hakeem Source Type: research

Transfusion practice, post-transfusion complications and risk factors in sickle cell disease in senegal, west africa.
Conclusion: Despite advances in blood safety, BT therapy is still a risk for SCD polytransfused patients. Although infectious transmission has rare, the risk of alloimmunization and iron overload is high in these patients. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Moussa Seck, Alioune Badara Senghor, Mossane Loum, Sokhna Aissatou Tour é, Blaise Félix Faye, Alioune Badara Diallo, Mohamed Keita, Elimane Seydi Bousso, Sérigne Mourtalla Guèye, Macoura Gadji, Abibatou Sall, Awa Oumar Touré, Saliou Diop Source Type: research

Nurses ’ physical and psychological symptoms during the first covid-19 lockdown in italy
Conclusions: different COVID-19 incidence among territories did not influenced nurses ’ burden of symptoms in HSCT setting. However, burnout and insomnia levels should be considered by health care facilities in order to improve preventive strategies. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Stefano Botti, Chiara Cannici, Sarah Liptrott, Valentina De Cecco, Elena Rostagno, Gianpaolo Gargiulo, Laura Orlando , Caime Alessandro, Emanuela Samarani, Letizia Galgano, Marco Cioce, Nicola Mordini, Nadia Mandelli, Lucia Tombari, Sara Errichiello, Nic Source Type: research

A THE EFFECT OF ALPHA THALASSEMIA, HBF and HBC ON HAEMATOLOGICAL PARAMETERS OF SICKLE CELL DISEASE PATIENTS IN IBADAN, NIGERIA.
Conclusions:Hematological parameters varied with hemoglobin genotype. The C hemoglobin and homozygous alpha thalassemia deletion had better ameliorating effect on SCD hematological parameters than the F hemoglobin in this population.  (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: FASOLA ATINUKE Source Type: research

Obituary of Prof. Eligio Pizzigallo
Obituary fo Prof. Eligio Pizzigallo (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Giuseppe Leone Source Type: research

Obituary of Prof. Michele Baccarani
Obituary of Prof. Baccarany (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Elisabetta Abruzzese Source Type: research

The impact of the SARS-CoV-2 pandemic on healthcare provision in Italy to non-COVID patients: a systematic review
ConclusionsOur work highlights the changes taking place in the Italian public healthcare system to tackle the developing health crisis due to the COVID-19 pandemic. The findings of our review may be useful to analyze future directions for the healthcare system in the case of new pandemic scenarios.  (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Annarita Botta, Gianmarco Lugli, Matteo Maria Ottaviani, Guido Ascione, Alessandro Bruschi, Federico Cagnazzo, Lorenzo Zammarchi, Paola Romagnani, tommaso portaluri Source Type: research

Congenital neutropenia in children: common clinical sceneries and clues for management
A disparate group of rare hematological diseases characterized by impaired maturation of neutrophil granulocytes defines congenital neutropenias. Neutropenic patients are prone to recurrent infections beginning in the first months of life. Of interest is “cyclic neutropenia”, an ultra-rare disorder revealed by sinusoidal variations of the neutrophil count and periodically-recurring infections every 21 days. Diagnosis of these disorders is frequently obscured by the multiple causes of recurrent fevers in children. Aim of this overview is to outli ne the physical assessment of children presenting with early-ons...
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: Donato Rigante Source Type: research

Mechanism of sars-cov-2 invasion into the liver and hepatic injury in patients with covid-19
A large number of studies have shown that patients with Coronavirus disease 2019 (COVID-19) have different degrees of liver injury. However, the mechanisms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invasion into the liver are still not fully understood. This review mainly summarizes the recently published works on the abnormal liver biochemical indicators and the mechanism of viral invasion with liver injury in COVID-19 patients. Generally, SARS-CoV-2 infection of the liver was caused by blood circulation or retrograde infection of digestive tract, which led to the liver injury through direct cyt...
Source: Mediterranean Journal of Hematology and Infectious Diseases - January 1, 2022 Category: Hematology Authors: XiaoTian Zhang, Yanhui Yu, Chao Zhang, Lijuan Zhao, Hongrui Wang, Guoqing Wang, Ming Yang Source Type: research