Mediterranean Journal of Hematology and Infectious Diseases This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The correlation of ineffective erythropoiesis biomarkers and development of extramedullary hematopoiesis in patients with thalassemia
Conclusions:Advanced age and high PS-exposed RBC levels are associated with EMH in thalassemia. PS-exposed RBCs showed a modest correlation with EMH and may be used to predict the development of EMH in thalassemia. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Siriyakorn Chansai, Supawadee Yamsri, Supan Fucharoen, Goonnapa Fucharoen, Nattiya Teawtrakul Source Type: research

Identification of Alpha Thalassemia, RNF 213 p.R4810K and PROC p.R189W among Children with Moyamoya Disease/Syndrome
(Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Lunliya Thampratankul, Yusuke Okuno, Patcharee Komvilaisak, Duangrurdee Wattanasirichaigoon, Nongnuch Sirachainan Source Type: research

Can Polycythemia Vera evolve from Acute Myeloid Leukemia? A Case Report Showing a Simultaneous Minor JAK2 V617F Mutated Clone,
Evolution of myeloproliferative neoplasms (MPN) to acute myeloid leukemia (AML) occurs in 2-10% of patients, whereas the reverse path from AML to MPN has been rarely reported.We herein present a 75-year-old woman with AML, in whom aJAK2-V617F positive polycythemia vera (PV) emerged during follow-up, 19 months from end of consolidation treatment.JAK2-V617F mutation screening retrospectively performed by Next Generation Sequencing (NGS) andJAK2 MutaScreen was negative on the bone marrow sample collected at AML diagnosis. However, using droplet digital PCR (ddPCR), we detected a minorJAK2-V617F mutated clone present at AML on...
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Beatrice Borsellino, Arianna Savi, Maria Rosaria Pascale, Elisa Meddi, Antonio Cristiano, TIZIANA OTTONE, Maria Cristina Rapanotti, Mariadomenica Divona, SERENA TRAVAGLINI, Enrico Attardi, Elisa Buzzatti, Francesco Buccisano, Maria Teresa Voso Source Type: research

Circctnna1 is upregulated in mantle cell lymphoma and predicts poor survival by sponging mir-34a to increase cell proliferation.
Conclusion:Upregulation of circCTNNA1 in MCL predicts poor survival of patients and it may sponge miR-34a to promote cancer cell proliferation. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Xuebing Jing, Cong Lu, Chao Song, Qingkun Han Source Type: research

Ident İfİcatİon of leİshmanİa tropİca from pedİatrİc vİsceral leİshmanİasİs İn southern mediterranean region of turkey.
Conclusions: The presence ofL. tropica in VL patients, despite the absence of cutaneous findings in any of the cases, shows that this strain can cause VL, contrary to conventional knowledge. In the Adana province, where this study was carried out,L. infantum from CL cases in previous studies should be taken into account and visceral spread in CL cases and accompanying cutaneous lesions in VL cases should be investigated in detail.Key Words;Visceral leishmaniasis, DNA Sequencing,Leishmania infantum, Leishmania donovani, Leishmania tropica (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Derya Alabaz, Fadime Ero ğlu, Hüseyin Elçi, Ümmühan Çay Source Type: research

Efficacy of monoclonal antibodies association in presence of two sars-cov-2 dominant variant of concern. comparative study versus monotherapy against a single variant: a real experience in umbria, italy.
ConclusionsOur data are in line with other experiences drawn from real life but show a higher hospitalization risk than that observed in the randomized trials which were performed before the spread of VOCs (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Elisabetta Schiaroli, Giuseppe Vittorio De Socio, Anna Gidari, Lisa Malincarne, Sara Benedetti , Alessandra Lanzi, Sabrina Bastianelli, Sara Pierucci, Chiara busti, Daniela Francisci Source Type: research

Usp9x increased tumor angiogenesis in mantle cell lymphoma by upregulation of ccnd1- mediated sox11
In conclusion, these results revealed that USP9X promoted tumor angiogenesis in MCL via increasing CCND1- mediated SOX11. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Gang Huang, Jianjun Liao, Mingli Wang, Yali Huang, Mingjie Tang, Yanyan Hao Source Type: research

The role of serial radiographs to diagnose diabetic foot bone infection.
Conclusion: Progressive bony changes detected by serial radiographs are a useful tool to diagnose diabetic foot osteomyelitis. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: ANTONIO LEONE, Nicola Carlo BIANCO, Giulia D ' AMBRA, Salvatore LUCCHESI, Elisa LA ROSA, Amato INFANTE, Daniele PERLA, Consolato GULLI ' Source Type: research

Back to the “gold standard”: how precise is hematocrit detection today?
Conclusions: This study introduces " micro-HCT " assessment technique using the image-analysis module of " ImageJ " software. This procedure allows overcoming most of the data errors associated with the standard " micro-HCT " evaluation and can replace the use of complicated and expensive automated equipment. The presented results may be also used to develop new standards for calculations of hematocrit and associated parameters for routine clinical practice. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Dr. Leonid Livshits, Ms. Tal Bilu, Ms. Sari Peretz, Prof. Anna Bogdanova, Prof. Max Gassmann, Dr. Harel Eitam, Prof. Ariel Koren, Prof. Carina Levin Source Type: research

The role of white blood cell count in perianal pathologies: a retrospective analysis of hematologic malignancies
Conclusions: In conclusion, this article has shown that white blood cell count at the time of hospitalization in patients with hematological malignancy, can affect the operation status of patients due to anal pathologies that may occur in the neutropenic period. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Bedrettin Orhan, Fahir Özkalemkaş, Vildan Özkocaman, Büşra Gürbüz, Tuba Ersal, İbrahim Ethem Pınar, Cumali Yalçın, Ömer Candar, Sinem Çubukçu, Tuba Güllü Koca, Rıdvan Ali Source Type: research

Renal abnormalities among sickle cell disease patients in a poor management setting: a survey in the democratic republic of the congo
Conclusions: This study highlighted that albuminuria and chronic kidney disease are common in SCD patients in Kisangani. More studies are needed to document these complications further.Keywords: Sickle cell disease, prevalence, sickle cell nephropathy, renal abnormalities, Democratic Republic of the Congo, sub-Saharan Africa. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 29, 2022 Category: Hematology Authors: Paul Kambale-Kombi, Roland Marini Djang ’eing’a, Jean-Pierre Alworong’a Opara, Jean-Paulin Mbo Mukonkole, Vincent Bours, Dieu-Merci Mbumba Lupaka, Serge Tonen-Wolyec, Lucien Bolukaoto Bome, Charles Kayembe Tshilumba, Salomon Batina-Agasa Source Type: research

Has hematopoietic stem cell transplantation a role in the treatment of children and adolescents with acute promyelocytic leukemia?
The past three decades have brought major therapeutic advances in the treatment of acute promyelocytic leukemia (APL) both in adults and children. The current state-of-the-art treatment with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) in combination or not with chemotherapy results in long-lasting remission and cure in more than 90% of newly diagnosed patients. These treatments have made relapse a rare event. The detection of PML-RARA transcript by polymerase chain reaction (PCR) during treatment and follow-up can predict a hematological relapse. All studies have suggested a survival benefit in patients with ...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Anna Maria Testi Source Type: research

De novo and therapy-related myelodysplastic syndromes: analogies and differences
The aim of our review has been to give an appropriate idea of analogies and differences between primitive MDS (p-MDS) and t-MDS throughout an accurate reviewing of English peer-reviewed literature focusing on clinical, cytogenetic, epigenetic, and somatic mutation features of these two groups of diseases.Therapy-related MDS (t-MDS) are classified by WHO together with therapy-related acute myeloid leukemia (t-AML) in the same group, named therapy-related myeloid neoplasm.However, in clinical practice, the diagnosis of t-MDS is made with the same criteria as for primitive MDS (p-MDS), and the only difference is a previous no...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Prof. Giuseppe Leone, Dr. Emiliano Fabiani, Prof. Maria Teresa Voso Source Type: research

Treatment of indolent and advanced systemic mastocytosis
Management of Indolent and Smoldering SM is focused on preventing anaphylactic reactions, identifying and avoiding symptom triggers. Skin and gastrointestinal symptoms are managed with H1- and H2-antihistamines. When skin symptoms are not adequately controlled, leukotriene antagonists and oral psoralen combined with ultraviolet therapy may be added. Proton pump inhibitors, sodium cromolyn and oral corticosteroids may be added for gastrointestinal symptoms. Patients should be prescribed with self-injectable epinephrine and trained to treat recurrent cardiovascular symptoms or anaphylaxis. Depression and cognitive impairment...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Dr. Alessandro Buonomo, Dr. Eleonora Nucera, Dr. Marianna Criscuolo Source Type: research

Epidemiological and clinical characteristics of pediatric covid-19 in the tertiary care system in thailand: comparative delta and pre-delta era
Conclusion: Pediatric COVID-19 during Delta era appeared generally more transmissible but benign. One-fifth of cases had pneumonia, but few cases needed respiratory support. Prevention remains important for disease control.Keywords: Pediatric, COVID-19, SARS-CoV-2, Delta, Epidemiology  (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 28, 2022 Category: Hematology Authors: Araya Satdhabudha, Chanapai Chaiyakulsil, Paskorn Sritipsukho, Phakatip Sinlapamongkolkul, Utairat Chaumrattanakul, Auchara Tangsathapornpong, Pornumpa Bunjoungmanee, Patcharapa Thaweekula, Amolchaya Kwankuac, Onsuthi Pharadornuwata, Tananya Source Type: research