Attitudes and practice patterns of Finnish obstetrician-gynecologists regarding patients' sexual problems
Sexuality is an important aspect of quality of life [1,2]. However, sexual problems are common, with the prevalence of female sexual dysfunction (FSD) ranging from 40  % to 50 %, irrespective of age [3]. Many different health care professionals—for instance, certified nurses, sexuality educators, sexuality counselors, and sexuality therapists, as well as physicians in various fields—take part in the management of sexual problems. Obstetrician-gynecologist s (OB/GYNs) are some of the key health care professionals who diagnose and treat female sexual problems, but previous studies have reported that OB/GYNs underesti...
Source: Maturitas - April 12, 2024 Category: Primary Care Authors: Anna Aromaa, P äivi Polo-Kantola, Sanna-Mari Manninen, Jarna Grönlund, Markus Riskumäki, Tero Vahlberg, Katja Kero Tags: Original article Source Type: research

Imaging and molecular features of adenomyosis after menopause
Adenomyosis is a benign gynecological disorder, characterized by the presence of endometrial epithelium (stroma and glands) within the myometrium, surrounded by smooth muscle hyperplasia [1]. The impaired expression of genes related to epithelial-mesenchymal transition, inflammation and fibrosis has been shown in adenomyotic lesions [2 –4]. The clinical presentation may include heavy menstrual bleeding (HMB), pelvic pain, dysmenorrhea, infertility and recurrent pregnancy loss [5,6]. (Source: Maturitas)
Source: Maturitas - April 11, 2024 Category: Primary Care Authors: Silvia Vannuccini, Silvia Gabbrielli, Francesca Castiglione, Eleonora Nardi, Margherita Rossi, Gretha Orlandi, Elisa Wu, Francesca Bertoli, Vittorio Miele, Chiara Donati, Felice Petraglia Tags: Original article Source Type: research

Editorial Board
(Source: Maturitas)
Source: Maturitas - April 5, 2024 Category: Primary Care Source Type: research

Hormone therapy in women with benign breast disease – What little is known and suggestions for clinical implementation
Benign breast disease encompasses a spectrum of non-malignant conditions within the breast, characterized by variations in both histological features and clinical manifestations. These conditions can be categorized into non-proliferative lesions, proliferative lesions without atypia, and proliferative lesions with atypia, each of which carries differing degrees of risk for future breast cancer development. The increased utilization of screening mammography has notably contributed to the rising detection of these lesions over the years [1]. (Source: Maturitas)
Source: Maturitas - April 5, 2024 Category: Primary Care Authors: Sabrina K. Sahni, Jessica L. Fraker, Lauren F. Cornell, Christine L. Klassen Tags: Review article Source Type: research

Menopause in the workplace: Challenges, impact, and next steps
Work Ability Index (Source: Maturitas)
Source: Maturitas - April 2, 2024 Category: Primary Care Authors: Nancy Safwan, Mariam Saadedine, Chrisandra L. Shufelt, Ekta Kapoor, Juliana M. Kling, Rajeev Chaudhry, Stephanie S. Faubion Tags: Review article Source Type: research

Evaluation of muscle and bone composition and function in aging women with polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a complex hormonal and metabolic disorder affecting up to 20  % of women in reproductive years [1]. The syndrome is associated with several comorbidities, including type 2 diabetes mellitus, hepatosteatosis, dyslipidemia, hypertension, endometrial cancer, sleep disorders, depression, and anxiety [2,3]. (Source: Maturitas)
Source: Maturitas - March 31, 2024 Category: Primary Care Authors: Burcu Çelik Eroğlu, Levend Karaçoban, Ilkay S. Idılman, Feza Korkusuz, Bulent Okan Yıldız Tags: Original article Source Type: research

The effects of lifestyle and behavioural interventions on cancer recurrence, overall survival and quality of life in breast cancer survivors: A systematic review and network meta-analysis
Breast cancer is the most prevalent malignancy and the leading cause of death from cancer among women, comprising 24.2  % of new cancer cases and 15 % of cancer deaths globally [1]. Advances in early diagnosis and treatment contribute to a 90 % 5-year relative survival rate, underscoring the importance of tailored survivorship care for women with breast cancer [2]. (Source: Maturitas)
Source: Maturitas - March 29, 2024 Category: Primary Care Authors: Ladan Yeganeh, Suzanne Willey, Ching Shan Wan, Mahnaz Bahri Khomami, Mohammad Chehrazi, Olivia Cook, Kate Webber Tags: Review article Source Type: research

An effective non-hormonal option with high tolerability for mild to moderate symptoms of vaginal dryness associated with menopause
Vaginal dryness is a typical and bothersome atrophic symptom of women with genitourinary syndrome of menopause (GSM). This chronic-progressive condition becomes clinically apparent some years after the onset of menopause [1]. As the average age of natural menopause ranges from 51 to 52  years in Germany and other industrialized countries, women over 50 years of age are most at risk of being affected by GSM [2]. Even though vaginal dryness can occur at any age, it specifically concerns women in the postmenopausal phase with a prevalence rate of>50  % [1,3,4]. (Source: Maturitas)
Source: Maturitas - March 28, 2024 Category: Primary Care Authors: Susann Eichler, Mareike Panz, Anastasia Harder, Clarissa Masur, Manuel H äuser, Erik Schulze zur Wiesche Tags: Original article Source Type: research

Moderate-intensity continuous training and high-intensity interval training modulate the composition of the oral microbiota of elderly adults: Randomized controlled trial
Joshua Lederberg, a geneticist and Nobel prize laureate in 1958, first coined the term microbiome as a community of commensal, symbiotic, and pathogenic micro-organisms [1]. The microbial colonization of the human body starts before birth, with a primary fetal colonization [2], then, the diversity, stability, and complexity evolves influenced by age, sex, development of the immune system and environmental factors for three years. Afterwards, the microbial colony remains stable in healthy adults and becomes unstable again when elderly. (Source: Maturitas)
Source: Maturitas - March 24, 2024 Category: Primary Care Authors: Mar ía Leyre Lavilla-Lerma, Agustín Aibar-Almazán, Antonio Martínez-Amat, José Daniel Jiménez-García, Fidel Hita-Contreras Tags: Original article Source Type: research

Association of age at menarche, reproductive lifespan and age at menopause with the risk of atrial fibrillation: The HUNT study
Age at menarche, reproductive lifespan, and age at menopause are associated with several cardiovascular diseases, but their relationship with atrial fibrillation (AF) is uncertain. (Source: Maturitas)
Source: Maturitas - March 24, 2024 Category: Primary Care Authors: Hikaru Morooka, Eirin B. Haug, Vegard Malmo, Jan P ål Loennechen, Kenneth Mukamal, Janet Rich-Edwards, Abhijit Sen, Imre Janszky, Julie Horn Tags: Original article Source Type: research

Menopause transition and cardiovascular disease risk
Cardiovascular disease (CVD) remains the leading cause of mortality in women, where one woman dies every eighty seconds from heart disease, exceeding mortality from all cancers combined [1]. The risk of CVD significantly increases in the fifth decade of a woman's life, occurring a decade later than the similar age-related increase in men [1]. This coincides with the onset of menopause which typically manifests at a mean age of 52  years [2]. While traditional CVD risk factors such as hypertension, hyperlipidemia, diabetes, smoking, and family history of premature CVD are valuable for assessing overall CVD risk in both me...
Source: Maturitas - March 22, 2024 Category: Primary Care Authors: Erin Uddenberg, Nancy Safwan, Mariam Saadedine, Maria D. Hurtado, Stephanie S. Faubion, Chrisandra L. Shufelt Tags: Review article Source Type: research

Female-specific risk variables: From innocent bystanders to key players in cardiovascular risk prediction
acute coronary syndrome (Source: Maturitas)
Source: Maturitas - March 21, 2024 Category: Primary Care Authors: Angela H.E.M. Maas Tags: Opinion paper Source Type: research

Nutrition of aging people with diabetes mellitus: Focus on sarcopenia
Medical advancement has led to a remarkable rise in life expectancy. However, with increasing age, metabolic and musculoskeletal diseases often accumulate. Notably, Type 2 diabetes mellitus (T2DM) and sarcopenia are conditions that disproportionally affect the elderly; in a US study, 28  % of the population aged over 50 who had the former also had the latter [1]. In 2021, the global population with diabetes was estimated at 537 million people, constituting 10.5 % of the world's population, while the prevalence surges to 24.0 % among adults aged 75–79 [2]. (Source: Maturitas)
Source: Maturitas - March 21, 2024 Category: Primary Care Authors: Almog Shalit, Eleni Gerontiti, Georgios Boutzios, Eleni Korakianiti, Fotini Kanouta, Vasiliki Vasileiou, Theodora Psaltopoulou, Stavroula A. Paschou Tags: Review article Source Type: research

Development and validation of an intrinsic capacity score in the UK Biobank study
In 2015, the General Assembly of the United Nations adopted the 2030 Agenda for Sustainable Development. Of the 17 sustainable development goals, the first was to ensure that all human beings are able to fulfill their potential. In the same year, the World Health Organization (WHO) introduced the concept of intrinsic capacity (IC) to guide our understanding of the realization of that potential [1]. The conceptual roots of IC can be traced to the writings of the philosopher Martha Nussbaum [2] who defined health and wellbeing in terms of people's capacities, i.e. (Source: Maturitas)
Source: Maturitas - March 16, 2024 Category: Primary Care Authors: Melkamu Bedimo Beyene, Renuka Visvanathan, Muktar Ahmed, Beben Benyamin, John R. Beard, Azmeraw T. Amare Tags: Original article Source Type: research

Laparoscopically confirmed endometriosis and anti-M üllerian hormone levels: Findings from the Nurses' Health Study II
Anti-m üllerian hormone (AMH) is secreted by granulosa cells in the ovaries in proportion to the number of developing follicles [1]. As a woman ages, her AMH steadily declines which mirrors the decline in the number of available oocytes for ovulation [2]. While AMH does not predict pregnancy success in wo men trying to conceive, it is associated with oocyte yield, infertility diagnoses, and time to menopause. AMH has become a commonly used proxy for clinically monitoring declines in ovarian function [2,3]. (Source: Maturitas)
Source: Maturitas - March 14, 2024 Category: Primary Care Authors: Leslie V. Farland, Michelle Valenti, William J. Degnan, Elizabeth R. Bertone-Johnson, Holly R. Harris, Amy D. DiVasta, Kathryn M. Rexrode, A. Heather Eliassen, Stacey A. Missmer Tags: Original article Source Type: research