Imaging and molecular features of adenomyosis after menopause

Adenomyosis is a benign gynecological disorder, characterized by the presence of endometrial epithelium (stroma and glands) within the myometrium, surrounded by smooth muscle hyperplasia [1]. The impaired expression of genes related to epithelial-mesenchymal transition, inflammation and fibrosis has been shown in adenomyotic lesions [2 –4]. The clinical presentation may include heavy menstrual bleeding (HMB), pelvic pain, dysmenorrhea, infertility and recurrent pregnancy loss [5,6].

Source: Maturitas - April 11, 2024 Category: Primary Care Authors: Silvia Vannuccini, Silvia Gabbrielli, Francesca Castiglione, Eleonora Nardi, Margherita Rossi, Gretha Orlandi, Elisa Wu, Francesca Bertoli, Vittorio Miele, Chiara Donati, Felice Petraglia Tags: Original article Source Type: research