The impact of environmental factors on ovarian aging: Is our human reproductive capacity actually diminishing?
Environmental modifications linked to climate change, added to environmental toxins, have an impact on the reproductive health of the population. The endocrine disruptors present in our environment, through different mechanisms, affect the correct hormonal functioning. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Yanina Laura Alicia Az ás Tags: Abstract ID: 171 Source Type: research

Effects of exogenous sex hormone use on sleep and depression: lessons learned from transgender users of gender-affirming hormones
This study examined the effects of sex hormone use (also called gender-affirming hormone therapy, or GAHT) by transgender persons on reported depressive symptoms and sleep quality. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Margot W.L. Morssinkhof, Daan van den Ende, Karin van der Tuuk, Chantal Wiepjes, Baudewijntje Kreukels, Guy T'Sjoen, Odile van den Heuvel, Ysbrand van der Werf, Martin den Heijer, Birit F.P. Broekman Tags: Abstract ID: 177 Source Type: research

Impact of LNG IUS on levels of sex hormone-binding globulin for women with a normal and elevated body mass: 1-year follow-up
Objective: Use of the LNG IUS is associated with weight changes, which are commonly cited by users and doctors as a side effect of the method. It is often the reason to stop using it. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Ineta Vasaraudze, Renars Erts Tags: Abstract ID: 184 Source Type: research

A multidisciplinary approach to the care for women in the menopausal transition: the view of the fertility specialist
Menopause and Fertility (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Basil C. Tarlatzis Tags: Abstract ID: 186 Source Type: research

Evaluation of quality of life in women with premature ovarian insufficiency who are taking hormone replacement therapy
Context: Spontaneous Premature Ovarian Insufficiency (POI) has many long-term adverse effects of estrogen deficiency. Symptoms include infertility, vasomotor and vulvovaginal atrophy symptoms, sexual dysfunction, increased risk of depression and anxiety, and increased rates of age-associated diseases at young age. Physiologic hormone replacement therapy (HRT) is considered standard care for women with POI. The goal of HRT is to reduce the effects of estrogen deficiency and many of mentioned health risks, as well as to improve quality of life (QOL) to the level of healthy women. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Svetlana Yureneva, Victoria Averkova Tags: Abstract ID: 188 Source Type: research

Effects of obesity on menopausal transition
Menopause is a natural phase in woman ’s life. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Anna Kostrzak Tags: Abstract ID: 191 Source Type: research

Consequences of Functional Hypothalamic Amenorrhea (FHA) in youth on menopausal transition in elder women
Functional hypothalamic amenorrhea (FHA) is a chronic endocrine disorder caused by disturbances in pulsatile GnRH secretion, which leads to inhibition of the hypothalamic-pituitary-ovarian axis and the development of secondary amenorrhea. FHA accounts for 25% to 35% of secondary amenorrhea, making it the most common cause of secondary amenorrhea in our population. It is estimated that up to 17 million women in the world may suffer from FHA. Up to 50% of women who regularly practice sports may suffer from menstrual disorders, while 30% of them will present symptoms of secondary amenorrhea. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Anna Szeliga Tags: Abstract ID: 194 Source Type: research

Mind, body, soul: a phase-oriented, holistic approach to menopause in the workplace
The negative impact of menopause on the work-life and career decisions of women has gained importance in recent times. Addressing the specific needs of women in the years before and after menopause is both an issue of gender equality in the workplace, and an imperative in a labor market with a shortage of skilled workers. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Sabine Nitsche, Jennifer Chan de Avila Tags: Abstract ID: 196 Source Type: research

Efficacy of the Very Low-Calorie Ketogenic Diet (VLCKD) in postmenopausal women with obesity: better to be “owls” or “larks”?
Nutritional approaches (NA) are the cornerstone of obesity therapy, but their optimal design for postmenopausal women, a population with a high prevalence of obesity, is debated. In addition, recent studies have reported that chronotype (reflecting an individual's preference for sleep, eating and activity times over a 24h period) plays a role in both the development of metabolic comorbidities and in determining eating habits in obesity. However, little is known whether the chronotype can predict the efficacy of (NA) in postmenopausal women with obesity (PWO). (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Ludovica Verde, Annamaria Docimo, Giovanni Chirico, Nicola Tecce, Annamaria Colao, Luigi Barrea, Giovanna Muscogiuri Tags: Abstract ID: 198 Source Type: research

Invisible women: the absence of adequate menopause education in schools
Context: One third of women in Europe are estimated to be currently peri- or post-menopausal, yet there is an absence of menopause education in school curricula in most countries. Menopause was only added to the Relationship and Sex Education curriculum in England ’s secondary schools in 2020, with just one mention of the menopause in guidance materials. Anecdotally, it is believed the menopause remains a taboo both in schools and in wider society. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Rebecca Lewis, Tiegan Weatherhead, Magnus Harrison, Dan Reisel, Louise Newson Tags: Abstract ID: 200 Source Type: research

Overcoming barriers to health: diet and exercise habits in perimenopausal and menopausal women
Context: Menopause is associated with symptoms that restrict ability to exercise (such as fatigue, low mood and joint pain), and dietary and metabolic changes linked with dysbiosis, gastro-intestinal symptoms and weight gain. This increases risk of chronic diseases such as ischaemic heart disease, dementia and osteoporosis, that are also independently associated with hormone deficiency. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Sarah Glynne, Dan Reisel, Rebecca Lewis, Louise Newson Tags: Abstract ID: 202 Source Type: research

For women established on HRT, how effective is the addition of transdermal testosterone in improving symptoms beyond those related to sexual function?
In this study, we explored the impact on adding transdermal testosterone for women already established on standard HRT on their symptoms beyond sexual function. The study population was composed of women in our clinic who had been prescribed testosterone during the study period from 1 August 2021 – 1 February 2022. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Aini Kamal, Dan Reisel, Magnus Harrison, Louise Newson Tags: Abstract ID: 206 Source Type: research

The last great taboo: menopause discussions in the home and between generations
Context: Menopause was only added to the Relationship and Sex Education curriculum in secondary schools in England in 2020, so most perimenopausal and menopausal women have never received any formal menopause education. Conversations with friends and family may be the only source of information for many. However, taboos around menopause may limit discussion resulting in lack of knowledge about symptoms and management options. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Dan Reisel, Magnus Harrison, Rebecca Lewis, Louise Newson Tags: Abstract ID: 209 Source Type: research

Does one size fit all? The usefulness of menopause education across low and middle income countries
Approximately six million women, globally, will become menopausal annually, with 76% of these living in developing countries. Western studies show that the menopause transition is associated with an increased risk of cardiometabolic disease (CMD), cognitive decline and related risk factors. Longitudinal research found CMD risk factors are increasing, leading to the majority of deaths worldwide, particularly in low- and middle-income countries (LMICs). Data show that CMDs are associated with cognitive decline and subsequent dementia. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Nicole Jaff Tags: Abstract ID: 212 Source Type: research

The relationship between cortisol and sleep architecture in perimenopausal and postmenopausal women
Objectives: Women report worse sleep quality during and after the menopausal transition than in premenopause, but null or minimal alterations in sleep architecture have been found. Concentrations of cortisol seem to increase temporally during perimenopause. However, the associations between cortisol and sleep architecture in women around the menopausal transition have not been examined in detail to date. (Source: Maturitas)
Source: Maturitas - June 8, 2023 Category: Primary Care Authors: Elena Toffol, Nima Sahola, P äivi Polo-Kantola Tags: Abstract ID: 217 Source Type: research