Menopausal hormone therapy: A review of metabolic and thermogenic effects
Around 85 % of women experience menopausal symptoms, and menopausal hormone therapy (MHT) is recognised as the most effective treatment, achieving reductions of over 75 % in the frequency and severity of these symptoms. Despite this, women are reluctant to start or continue MHT, often because of concerns about an increased risk of breast cancer and a belief that it can lead to weight gain. (Source: Maturitas)
Source: Maturitas - March 11, 2024 Category: Primary Care Authors: Susanna Weidlinger, Petra Stute Tags: Editorial Source Type: research
Potentially modifiable risk factors for dementia in six low-income and middle-income countries: A multinational, population-based survey
Dementia is a global public health emergency [1]. Worldwide, in 2019, there were 55 million living with dementia, with the number projected to triple by 2050 [2]. The economic cost of dementia is also expected to increase from US$ 4.7 trillion in 2019 to US$ 16.7 trillion in 2050 [3]. However, there is a geographic disparity in the burden of dementia. By 2050, two-thirds of the people living with dementia will be housed in low and middle-income countries (LMICs), reflecting a vertiginous increase in the economic burden in these regions. (Source: Maturitas)
Source: Maturitas - March 9, 2024 Category: Primary Care Authors: Natan Feter, Jayne S. Feter, Wyllians V. Borelli, Airton J. Rombaldi, Raphael M. Castilhos Tags: Original article Source Type: research
Sleep duration in midlife and old age and risk of mortality over a 48-year follow-up: The Helsinki businessmen study (HBS) cohort
Sleep has become an increasingly popular topic of discussion, particularly in relation to the impact of modern, fast-paced lifestyles on sleep disorders and the common use of sleep medications. Poor sleep naturally affects daytime performance, and both insufficient sleep and excessive sleep have been associated with various diseases and health conditions in observational studies [1 –14]. As a result, sleep is included also in the American Heart Association's Life's Essential 8 (LE8) metrics [15]. (Source: Maturitas)
Source: Maturitas - March 7, 2024 Category: Primary Care Authors: Timo E. Strandberg, Kaisu H. Pitk älä, Mika Kivimäki Tags: Original article Source Type: research
Levels of frailty and frailty progression in older urban- and regional-living First Nations Australians
First Nations Australians account for 3.8 % of the Australian population [1]. First Nations Peoples and cultures are diverse, and comprise many nations [2]. First Nations Australians experience well-known health inequity and socioeconomic disadvantages; the legacy of colonisation, discrimination and structural racism still contributes to these inequalities [3]. While there have been increasing gains in some areas, this population still have worse health than their non-Indigenous counterparts, lower life expectancies and disproportionately higher levels of chronic disease [4]. (Source: Maturitas)
Source: Maturitas - March 5, 2024 Category: Primary Care Authors: Ebony T. Lewis, Kaarin J. Anstey, Kylie Radford, Nicole Mealing, Magnolia Cardona, Adrienne Withall, Kenneth Rockwood, Ruth Peters Tags: Original article Source Type: research
Public expenditure on health care and the incidence of non-communicable diseases (NCDs) in China from 2008 to 2018
Non-communicable diseases (NCDs) are the leading cause of morbidity and mortality globally. WHO estimates state that approximately 41 million people die from NCDs each year, and NCDs account for 74 % of the global deaths [1]. Previously often assumed to be diseases mainly associated with wealthier countries, NCDs are in reality a very important and growing challenge in many low and middle-income countries (LMICs) [2]. The poor, vulnerable and those from socially disadvantaged groups are ofte n most likely to be affected by NCDs. (Source: Maturitas)
Source: Maturitas - March 4, 2024 Category: Primary Care Authors: Zhixin Feng, Xiaoting Liu, Wei Yang, David R. Phillips Tags: Original article Source Type: research
Vulvovaginal atrophy in women with and without a history of breast cancer: Baseline data from the PatiEnt satisfactiON studY (PEONY) in Italy
Both hormonal deprivation and senescence contribute to significant changes in the functional anatomy of urogenital tissues giving origin to signs and symptoms of vulvovaginal atrophy (VVA) [1]. Main symptoms of VVA (vaginal dryness, irritation, itching, and dyspareunia) were included into the new definition of genitourinary syndrome of menopause [2] and ranged from 13 % to 87 % according to different study samples [3]. For instance, in a cohort of women with a history of breast cancer (BC), vaginal dryness was present in 61.5 % of postmenopausal women [4]. (Source: Maturitas)
Source: Maturitas - March 4, 2024 Category: Primary Care Authors: Maria Cristina Meriggiola, Paola Villa, Silvia Maffei, Angelamaria Becorpi, Tiziana Di Paolantonio, Antonio Nicolucci, Stefano Salvatore, Rossella E. Nappi, PEONY Study Group Tags: Original article Source Type: research
Public expenditure on health care and the incidence of non-communicable diseases (NDCs) in China from 2008 to 2018
Non-communicable diseases (NCDs) are the leading cause of morbidity and mortality globally. WHO estimates state that approximately 41 million people die from NCDs each year, and NCDs account for 74 % of the global deaths [1]. Previously often assumed to be diseases mainly associated with wealthier countries, NCDs are in reality a very important and growing challenge in many low and middle-income countries (LMICs) [2]. The poor, vulnerable and those from socially disadvantaged groups are oft en most likely to be affected by NCDs. (Source: Maturitas)
Source: Maturitas - March 4, 2024 Category: Primary Care Authors: Zhixin Feng, Xiaoting Liu, Wei Yang, David R. Phillips Tags: Original article Source Type: research
Correlates of sexual and reproductive health service utilization among older adults in China: Findings from the sexual well-being (SWELL) study
The aging population is increasing globally. In 2021, 260 million people were older than 60 years old in China [1]. By 2050, China's older adults are expected to account for one-quarter of the total population [1]. Previous studies have shown that sexual health is an integral part of overall health in older age and older adults remain sexually active in later life [2]. The World Health Organization (WHO) reports that sexual activity can be enjoyable and fulfilling for older adults, but at the same time, they have greater co-morbidities and disabilities that may impact their sex life [3]. (Source: Maturitas)
Source: Maturitas - March 4, 2024 Category: Primary Care Authors: Xin Peng, Bingyi Wang, Xinyi Li, Yuwei Li, Yong Lu, Jiewei Liu, Lin Ouyang, Guohui Wu, Yong Cai, Maohe Yu, Joseph D. Tucker, Weiming Tang, Dan Wu, Xiaojun Meng, Huachun Zou Tags: Original article Source Type: research
Of a “certain age” – Menopause in Native American women: A cultural perspective
Clinicians dedicated to providing care for patients from diverse cultural backgrounds strive to ensure they give those patients comprehensive support. The cultural perspectives of these patients may significantly influence their openness to discussions regarding menopausal symptoms and potential management strategies. (Source: Maturitas)
Source: Maturitas - March 3, 2024 Category: Primary Care Authors: Denise Schweda, Jesse Bracamonte Tags: Editorial Source Type: research
Racial disparities in breast cancer risk factors and risk management
Breast cancer (BC) accounts for 31 % of all cancers in women in the United States (US), and rates are increasing by 0.5 % per year (possibly due to obesity and delayed childbearing) [1]. While mortality overall has decreased due to widespread screening and improved treatments, not all women have benefitted equally [1]. BC outcom e disparities between Black and White women, from diagnosis to treatment and survivorship, are significant and continue to widen. Although overall, Black women have a slightly lower overall BC incidence than White women [1], the incidence is actually higher among Black women until the age of 6...
Source: Maturitas - February 28, 2024 Category: Primary Care Authors: Holly J. Pederson, Zahraa Al-Hilli, Allison W. Kurian Tags: Review article Source Type: research
Two cosmoses, one universe: a narrative review exploring the gut microbiome's role in the effect of urban risk factors on vascular ageing
augmentation index (Source: Maturitas)
Source: Maturitas - February 27, 2024 Category: Primary Care Authors: Lara Anne Bridge, Juliana Alexandra Hern ández Vargas, Silvia Juliana Trujillo-Cáceres, Sara Beigrezaei, Angeline Chatelan, Amin Salehi-Abargouei, Taulant Muka, Julieth Pilar Uriza-Pinzón, Hamidreza Raeisi-Dehkordi, Oscar H. Franco, Gianfranco Grompone Tags: Review article Source Type: research
The impact of sustainable diets οn cognitive function in an ageing society: A mini-review
A significant increase in the population of older adults has been recorded during the recent decades and it is estimated that by 2050, the number of adults exceeding 60 years of age will have doubled [1]. On one hand, increased longevity is highly beneficial as life span lengthens, while on the other, longevity is not usually accompanied by a healthy status and a good quality of life. Even though, older adults are living longer, they are often at risk for chroni c diseases, cognitive and functional impairment, and disability [2]. (Source: Maturitas)
Source: Maturitas - February 27, 2024 Category: Primary Care Authors: Mary Gouela, Tonia Vassilakou, Anna Chaida, Anagnostis Argiriou Tags: Review article Source Type: research
Editorial Board
(Source: Maturitas)
Source: Maturitas - February 26, 2024 Category: Primary Care Source Type: research
Weight loss induced by a hypocaloric diet with or without fish oil supplementation re-established iron and omega-3 fatty acid homeostasis in middle-aged women with obesity: A post-hoc analysis of a randomized controlled trial
Obesity and iron-deficiency (ID) anemia (IDA) remain major global health concerns. The pathophysiology of obesity-related functional ID has linked adiposity-mediated inflammation to dysregulated iron metabolism [1]. Hepcidin-ferroportin interaction regulates iron homeostasis [2]. However, inflammation triggers an elevation in hepcidin levels, which results in a reduction of bioavailable iron, thereby impacting the support of erythropoiesis [3,4]. Consequently, patients with obesity and chronic disease may develop IDA and tissue iron overload [5]. (Source: Maturitas)
Source: Maturitas - February 24, 2024 Category: Primary Care Authors: Shih-Yi Huang, Noor Rohmah Mayasari, Te-Hsuan Tung, Wen-Ling Lin, Sung-Hui Tseng, Chun-Chao Chang, Hui-Yu Huang, Jung-Su Chang Tags: Original article Source Type: research
Exploring interconnections: A comprehensive multi-country analysis of climate change, energy demand, long-term care, and health of older adults
The intertwined challenges of climate change and energy insecurity have the potential to rollback improvements in older people's health and care. In 1950, approximately 128.2 million people were aged 65 and older, just 5.1 % of the world's population. Today, the world has 807.8 million older people, a six-fold increase accounting for 10 % of the global population. By 2050, there will be 1.6 billion persons aged 65 and older [1]. The health care challenges and diversity of long-term care needs among aging populati ons are often overlooked in global actions around climate change and energy demand. (Source: Maturitas)
Source: Maturitas - February 22, 2024 Category: Primary Care Authors: Keriin Katsaros, Clemens Marggraf, Kristie L. Ebi, Kareem Buyana, Masahiro Hashizume, Shih-Chun Candice Lung, Virginia Murray, Sokhna Thiam, Jo-Ting Huang-Lachmann Tags: Original article Source Type: research
