Editorial Board
(Source: Maturitas)
Source: Maturitas - January 10, 2024 Category: Primary Care Source Type: research
Age at first birth is associated with the likelihood of frailty in middle-aged and older women: A population-based analysis from NHANES 1999 –2018
Frailty is a common geriatric syndrome characterized by a progressive age-related decline in physiological systems and functional reserves that can lead to a high risk of adverse health outcomes, including falls, fractures, disability, hospitalization, cognitive impairment, and mortality [1,2]. With the rapid growth of aging populations worldwide, frailty is becoming a major public health concern. Pooled estimates of frailty prevalence measured in regard to physical phenotype (PP) and frailty index (FI) were 12 % and 24 %, respectively, in 62 countries across the world [3]. (Source: Maturitas)
Source: Maturitas - December 25, 2023 Category: Primary Care Authors: Hui-Jie Guo, Yi-Lu Ye, Yun-Fei Gao, Zhi-Hua Liu Tags: Original article Source Type: research
Could psychobiotics and fermented foods improve mood in middle-aged and older women?
Menopause, an inevitable stage in a female's reproductive life, is marked by declining estrogen levels, often leading to physiological and psychological changes [1]. This transformation, typically occurring between the ages of 45 and 55, is influenced by various factors, including genetics, lifestyle, and environmental elements [2]. Among menopausal changes, mood swings, anxiety, and depression emerge as the most frequently reported mood disorders [3]. These emotional changes can be attributed to the intricate interplay between hormones and neurotransmitters, as the body recalibrates to function without the same hormonal b...
Source: Maturitas - December 20, 2023 Category: Primary Care Authors: Souzan Zidan, Serene Hilary, Ayesha Al-Dhaheri, Leila Cheikh Ismail, Habiba I. Ali, Vasso Apostolopoulos, Lily Stojanovska Tags: Review article Source Type: research
Is weight loss a therapeutic tool in the management of male infertility?
Couple infertility, defined as the inability to conceive after at least one year of unprotected sexual intercourse, affects approximately 15 –20 % of couples of reproductive age. This condition is a clear example of gender disparity, since the female partner is largely evaluated and treated, while the male is generally reduced to a simple ‘sperm provider’. However, male factors are detectable in about half of cases, justifying a detailed diagnostic work-up aimed at identifying specific causes and potential therapeutic approaches [1]. (Source: Maturitas)
Source: Maturitas - December 19, 2023 Category: Primary Care Authors: Daniele Santi, Giovanni Corona Tags: Editorial Source Type: research
Quality of life in sarcopenia measured with the SarQoL questionnaire: A meta-analysis of individual patient data
Sarcopenia, consequential from the involuntary loss of muscle mass and function [1], is now recognized as a disease entity and figures in The International Statistical Classification of Diseases and Related Health Problems - Clinical Modification Code (ICD-10-CM, code M62.84) [2]. This multifactorial disease is associated with increased morbidity, mortality, falls, and physical disability and is currently suggested to impact health-related quality of life (HRQoL) [3 –7]. (Source: Maturitas)
Source: Maturitas - December 15, 2023 Category: Primary Care Authors: Charlotte Beaudart, No émie Tilquin, Pawel Abramowicz, Fátima Baptista, Dao Juan Peng, Fabiana de Souza Orlandi, Michael Drey, Marta Dzhus, Raquel Fábrega-Cuadros, Julio Fernandez-Garrido, Lucas Fornari Laurindo, Andrea-Ildiko Gasparik, Anton Geerinck, Tags: Review article Source Type: research
Editorial Board
(Source: Maturitas)
Source: Maturitas - December 6, 2023 Category: Primary Care Source Type: research
Menopause and accelerated aortic stiffness
Cardiovascular disease (CVD) is a leading cause of mortality and morbidity in women over the age of 50 years in most Western societies [1]. Although the risk of CVD increases with age in both sexes, the risk accelerates more sharply in postmenopausal women than in men [2,3]. This has led to the hypothesis that the menopausal transition may itself accelerate vascular aging, most notably through an increase in aortic stiffness [4]. An increase in aortic stiffness elevates left ventricular afterload, impedes normal coronary perfusion, and is an independent predictor of CVD morbidity and mortality [5–7]. (Source: Maturitas)
Source: Maturitas - December 4, 2023 Category: Primary Care Authors: Sheila M. O'Neill, Catherine M. Travers, Petr Otahal, Soo-Keat Khoo, James E. Sharman Tags: Original article Source Type: research
Body composition analysis: A snapshot across the perimenopause
Perimenopause starts from the first clinical, biological, and endocrine features of the approaching menopause, including vasomotor symptoms and menstrual irregularity, ending 12 months after the last menstrual period. It is experienced only with spontaneous (natural), as opposed to induced menopause [1]. This transition state is characterized by gradual loss of oocytes, altered responsiveness to gonadal steroid feedback and hormonal fluctuations with a gradual decline in serum estrogen concentrations [2]. (Source: Maturitas)
Source: Maturitas - November 30, 2023 Category: Primary Care Authors: Maria Karaflou, Dimitrios G. Goulis Tags: Review article Source Type: research
Impact of violence against women on quality of life and menopause-related disorders
Violence against women (VAW) is a pressing global issue that poses a number of significant health risks. Although we currently lack precise data on the number of women who have been victims of VAW, it is a pervasive social problem, with at least one in four women reaching menopause estimated to have experienced VAW [1]. (Source: Maturitas)
Source: Maturitas - November 29, 2023 Category: Primary Care Authors: Loreto Mendoza-Huertas, Nicol ás Mendoza, Débora Godoy-Izquierdo Tags: Original Article Source Type: research
Dispensing of antineoplastic medications and their impact on the dispensing of anti-dementia drugs for adults aged ≥60 years: A cohort study
Dementia is a leading cause of disability and death. There is currently no cure for dementia, so identifying and managing modifiable risk factors is essential. A systematic review of 36 longitudinal studies found that the risk of dementia was 11 % lower among cancer survivors compared with non-cancer adults [1], and a recent longitudinal study of 31,080 older men reported that the diagnosis of dementia was 15 % less frequent among those who had survived cancer for at least two years [2]. Moreover, the diagnosis of cancer has been assoc iated with lower burden of Alzheimer's disease (AD) neuropathology [3]. (Source: Maturitas)
Source: Maturitas - November 22, 2023 Category: Primary Care Authors: Osvaldo P. Almeida, Christopher Etherton-Beer, Frank Sanfilippo, David B. Preen, Amy Page Tags: Short Communication Source Type: research
“I can't be dealing with this brain fog”: A workplace focus group study investigating factors underpinning the menopausal experience for NHS staff
Lack of support for individuals undergoing menopause has been identified as a major issue for employers [1]. Menopause represents a significant time of change in a woman's life. While the average age of menopause transition in the UK is 51 [2], symptoms can stretch up to a decade either side [3], resulting in women potentially spending a substantial proportion of their careers experiencing menopausal symptoms. Surveys suggest that nearly two thirds of women working while experiencing symptoms of the menopause are negatively affected at work [4], with symptoms including vasomotor symptoms [5], reduced concentration [6] and ...
Source: Maturitas - November 22, 2023 Category: Primary Care Authors: Gemma Hobson, Nicola Dennis Tags: Original article Source Type: research
Ten-year incidence, predictors and impact of dizziness and vertigo in community-dwelling adults
Dizziness is a general term for a sense of disorientation. Vertigo is a subtype of dizziness, which is classified as an illusion of movement, usually a sense of rotation [1,2]. Dizziness (including vertigo) affects about 15 % to over 20 % of adults yearly in large population-based studies [2]. Research into risk factors for dizziness/vertigo is only in its infancy, but so far a consistent association of vertigo and migraine has been reported, which has advanced the recognition of vestibular migraine as a distinct vestibular syndrome [2]. (Source: Maturitas)
Source: Maturitas - November 22, 2023 Category: Primary Care Authors: Bamini Gopinath, Diana Tang, George Burlutsky, Paul Mitchell Tags: Original Article Source Type: research
Association between normal-weight obesity and bone mineral density in older Korean adults: A population-based cross-sectional study
Low bone mass and microarchitectural deterioration of bone tissue are the hallmarks of osteoporosis, a medical condition that results in brittle bone and elevates fracture risk. Osteoporotic fractures are a major health burden on the elderly population and the healthcare system, and this is especially true in South Korea [1,2], where the elderly population is growing at the fastest rate in the world [3]. (Source: Maturitas)
Source: Maturitas - November 20, 2023 Category: Primary Care Authors: Jeonghyeon Kim, Seamon Kang, Hyunsik Kang Tags: Original article Source Type: research
Effect of dietary diversity on incident of disability in community-dwelling older adults with sarcopenia: A 40-month follow-up longitudinal study
Population aging is a critical issue worldwide [1]. The Japanese have entered the era of super-aging and advanced health transition, which is increasingly putting pressure on the sustainability of its health system [2]. In 2012, the cost of Japan's long-term care insurance (LTCI) system, which is the cost of supporting persons with disabilities, was approximately US$880 billion and is expected to double by 2025 [3]. Therefore, prevention of functional disability is an important issue for public health in Japan and other counties. (Source: Maturitas)
Source: Maturitas - November 14, 2023 Category: Primary Care Authors: Yuto Kiuchi, Kota Tsutsumimoto, Takehiko Doi, Satoshi Kurita, Kazuhei Nishimoto, Hyuma Makizako, Hiroyuki Shimada Tags: Original Article Source Type: research
Telomerase activity and telomere length in women with breast cancer or without malignancy: A systematic review and meta-analysis
All eukaryotic cells have a series of repeated sequences of nucleotides (telomeres) at the end of chromosomes that protect from their degradation, chromosomal fusion, and irregular recombination. The molecular TTAGGG sequence of telomeres is a common feature of eukaryotes [1]. In humans, telomeres progressively shorten due to the incomplete replication of linear DNA to reach either cell senescence or apoptosis [1 –3]. Telomere length is influenced by diet, lifestyle, reproductive, age, and health factors [4–7]. (Source: Maturitas)
Source: Maturitas - November 12, 2023 Category: Primary Care Authors: Vicente A. Benites-Zapata, Juan R. Ulloque-Badaracco, Esteban A. Alarc ón-Braga, Ana M. Fernández-Alonso, María T. López-Baena, Faustino R. Pérez-López Tags: New investigator award Source Type: research
