Menopausal symptoms in midlife Singaporean women: Prevalence rates and associated factors from the Integrated Women's Health Programme (IWHP)
By 2025, 1.1 billion of the world's women will be postmenopausal [1]. Studying menopausal symptoms is vital for understanding their impact on relationships, work, and health [2,3]. Menopausal symptom prevalence is well-described in Caucasian populations [4,5]. Although a number of studies on vasomotor symptoms and other aspects of menopausal symptomatology in Asian women have been published [6], few have examined the association between menopausal symptoms and its constituent domains with health outcomes such as disability and muscle function. (Source: Maturitas)
Source: Maturitas - October 6, 2023 Category: Primary Care Authors: Susan Logan, Beverly Wen Xin Wong, Joelle Hwee Inn Tan, Michael S. Kramer, Eu-Leong Yong Tags: Original article Source Type: research

Editorial board
(Source: Maturitas)
Source: Maturitas - September 27, 2023 Category: Primary Care Source Type: research

Genes and environment: An old pair in a new era
According to Darwin, evolution is based on four processes: (i) there is variation in the population; (ii) this variation is heritable; (iii) there is competition between progeny with and without the variant(s); (iv) survival of the species and inheritance of the variation(s) are associated with successful outcome of the competition; these are not random processes [1]. In the Darwinian theory, in other words, the environment plays the role of an influencer, with natural selection being the ultimate shaper of future genetics, as Huxley proposed in his “Modern Evolutionary Synthesis”, but a full understanding of evolution...
Source: Maturitas - September 25, 2023 Category: Primary Care Authors: Constantine A. Stratakis Tags: Opinion paper Source Type: research

Influence of type of household on prognosis at one year in patients ≥65 years attending hospital emergency departments in Spain. The EDEN-6 study
The aging of the population is a worldwide phenomenon. The percentage of the population  ≥ 65 years has increased and will rise in the next few years [1]. In Europe, this population is expected to increase from 90.5 million in 2019 to 129.8 million by 2050 [2]. Elderly patients have a greater number of comorbidities and functional and cognitive limitations. As a result, they are n ot only more likely to become ill but also have atypical complaints and specific syndromes associated with frailty [3]. (Source: Maturitas)
Source: Maturitas - September 21, 2023 Category: Primary Care Authors: Aitor Alqu ézar-Arbé, Gina I. Osorio, Javier Jacob, Eric Jorge García-Lamberechts, Pascual Piñera Salmerón, Pere Llorens, Guillermo Burillo-Putze, Angela Cobos Requena, Adriana Gil, Cesáreo Fernández, Sira Aguiló, Sònia Jiménez, Beatriz Escudero Tags: Original article Source Type: research

Influence of type of household on prognosis at one year in patients ≥65 years attending hospital emergency departments in Spain. The EDEN-6 study
The aging of the population is a worldwide phenomenon. The percentage of the population  ≥ 65 years has increased and will rise in the next few years [1]. In Europe, this population is expected to increase from 90.5 million in 2019 to 129.8 million by 2050 [2]. Elderly patients have a greater number of comorbidities and functional and cognitive limitations. As a result, they ar e not only more likely to become ill but also have atypical complaints and specific syndromes associated with frailty [3]. (Source: Maturitas)
Source: Maturitas - September 21, 2023 Category: Primary Care Authors: Aitor Alqu ézar-Arbé, Gina I. Osorio, Javier Jacob, Eric Jorge García-Lamberechts, Pascual Piñera Salmerón, Pere Llorens, Guillermo Burillo-Putze, Angela Cobos Requena, Adriana Gil, Cesáreo Fernández, Sira Aguiló, Sònia Jiménez, Beatriz Escudero Tags: Original article Source Type: research

Association of circulating vitamin D and omega 3 fatty acid with all-cause mortality in patients with rheumatoid arthritis: A large population-based cohort study
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects around 0.46  % of the global population [1]. It is characterized by painful joint inflammation that can lead to cartilage and bone damage, joint dysfunction, disability, and a reduced quality of life. The etiology of RA remains not fully elucidated but is thought to result from a combination of genetic predis position, environmental factors, and immune dysregulation [2]. Despite recent advances in therapy, a cure for RA remains elusive and more effective treatments continue to be explored [3,4]. (Source: Maturitas)
Source: Maturitas - September 15, 2023 Category: Primary Care Authors: Siyu Chen, Shiqi Chen, Zhijian Zhao, Xueqing Cao, Zhangling Chen, Jun Lin Tags: Original Article Source Type: research

Long-term life satisfaction in ageing women with work disability due to mental and musculoskeletal disorders
The World Health Organization (WHO) has defined heathy ageing as a process of developing and maintaining functional ability, enabling physical, mental and social wellbeing [1]. Thus, there is a need for a realistic and multifaceted view of healthy ageing – covering both its objective and subjective dimensions – to understand and optimize overall health and wellbeing among ageing adults. (Source: Maturitas)
Source: Maturitas - September 15, 2023 Category: Primary Care Authors: J. Heikkinen, R.J. Honkanen, S.E. Quirk, L.J. Williams, H. Koivumaa-Honkanen Tags: Original Article Source Type: research

Sequential management of postmenopausal health and osteoporosis: An update
Increased life expectancy implies that women remain in a hypoestrogenic state for approximately one-third of their lives. The overall health status and specifically bone health during this period evolves in accordance with aging and successive exposure to various risk factors. (Source: Maturitas)
Source: Maturitas - September 12, 2023 Category: Primary Care Authors: Joaquin Calaf-Alsina, Antonio Cano, N úria Guañabens, Santiago Palacios, M. Jesús Cancelo, Camil Castelo-Branco, Ricardo Larrainzar-Garijo, José Luis Neyro, Xavier Nogues, Adolfo Diez-Perez Tags: Review article Source Type: research

Risk of endometrial polyp and surgical intervention in postmenopausal women with proliferative endometrium
Endometrial biopsy (EMB) is commonly performed in postmenopausal women to exclude endometrial cancer or hyperplasia (ECH) [1]. Most EMB results are benign; while the majority will have atrophic endometrium (AE), about 15  % are found to have proliferative endometrium (PE) [2–7]. The long-term clinical significance of the various benign endometrial histologies is poorly understood. PE histology includes formation of tubular glands, tall pseudostratified columnar cells and mitotic figures and has been associated w ith obesity. (Source: Maturitas)
Source: Maturitas - September 9, 2023 Category: Primary Care Authors: Ohad Rotenberg, Georgios Doulaveris, Dmitry Fridman, Malte Renz, Julie Kaplan, Xianhong Xie, Gary L. Goldberg, Pe'er Dar Tags: Original article Source Type: research

The role of estrogen in female skeletal muscle aging: A systematic review
Aging is associated with progressive loss of skeletal muscle mass concomitant to a reduction in muscle strength [1]. Independent of disease, muscle mass and strength decline by approximately 8  % and 15 % per decade from the fourth decade of life, with a rapid acceleration after 70 years [2]. This reduction in skeletal muscle health directly contributes to impaired physical function, impacting the independence and quality of life of older adults [3]. Older individuals demonstrate ce llular impairments that reduce muscle mass and function compared to young individuals, including blunted anabolic responses to exercise ...
Source: Maturitas - September 6, 2023 Category: Primary Care Authors: Annabel J. Critchlow, Danielle Hiam, Ross Williams, David Scott, S éverine Lamon Tags: Review article Source Type: research

Association of change in fat and lean mass with incident cardiovascular events for women in midlife and beyond: A prospective study using dual-energy x-ray absorptiometry (DXA)
There is association between adiposity and cardiovascular risk factors and incident events. To date, studies on the impact of longitudinal changes in adiposity on incident cardiovascular events have used anthropometric methods such as weight, BMI and waist circumference as surrogate measures of body fat [1 –4]. Imaging techniques including dual energy x-ray absorptiometry (DXA), CT and MRI have furthered our understanding of dysmetabolic states. Patients with metabolic abnormalities are characterized by increased visceral adipose tissue, whereas patients with a normal metabolic risk profile have low levels of visceral ad...
Source: Maturitas - September 1, 2023 Category: Primary Care Authors: Joseph C.H. Wong, Sheila O'Neill, Belinda R. Beck, Mark R. Forwood, Soo Keat Khoo Tags: Original article Source Type: research

Managing eating problems after cancer
In recent decades, advances in early cancer detection and treatment have led to improved survival [1], and combined with ageing and growing populations, this results in a steady increase in the number of cancer survivors in many countries [2,3]. Despite the advances in treatment strategies, an otherwise successful curative cancer treatment may pose other challenges. Cancer treatment can cause food-limiting eating problems and nutrition impact symptoms that may persist or present months or years after treatment completion [4,5]. (Source: Maturitas)
Source: Maturitas - August 27, 2023 Category: Primary Care Authors: Marianne Boll Kristensen Tags: Review article Source Type: research

Editors, publication ethics and maintaining the integrity of the scientific record
To maintain the integrity of the scientific record, journal editors aim to publish honest and reproducible papers free from data fabrication, falsification, duplication, salami slicing or plagiarism. Studies need to comply with international ethical guidelines and reporting standards. Publication of flawed research can be due to honest error or deliberate misconduct [1 –5]. In either case misinformation can affect others. Research funding can be wasted should others try to replicate the erroneous findings or use them as the basis of their own studies. (Source: Maturitas)
Source: Maturitas - August 24, 2023 Category: Primary Care Authors: Margaret Rees Tags: Editorial Source Type: research

Mediterranean diet for cancer prevention and survivorship
Cancer is one of the main non-communicable diseases (NCD) and is the second leading cause of death on a global level [1,2]. The International Agency for Research on Cancer estimates that 19.3 million new cases were diagnosed in 2020, with mortality at around 10 million [3] . Moreover, greater life expectancy worldwide is a major contributor, since aging is a high-risk factor. Cancer treatment and early detection are improving dramatically, resulting in an already large and growing population of survivors. (Source: Maturitas)
Source: Maturitas - August 23, 2023 Category: Primary Care Authors: Aitana Monllor-Tormos, Alicia Garc ía-Vigara, Orly Morgan, Miguel-Ángel García-Pérez, Nicolás Mendoza, Juan J. Tarín, Antonio Cano Tags: Review article Source Type: research

Editorial board
(Source: Maturitas)
Source: Maturitas - August 22, 2023 Category: Primary Care Source Type: research