Anxiety but not menopausal status influences the risk of long-COVID-19 syndrome in women living in Latin America
The severe acute respiratory syndrome coronavirus two (SARS-CoV-2) infection is associated with multiple symptoms and reactions included in the coronavirus disease-2019 (COVID-19) and long-COVID-19 (post-COVID-19, post-acute-COVID-19, or persistent COVID-19) syndrome [1 –3]. This prolonged syndrome affects 10 % of subjects surviving the acute infection, has a complex pathophysiology, and is more prevalent among females gender and older age [4,5]. The most common complaints are breathlessness, fatigue, and brain fog, although the clinical manifestations, severit y, laboratory findings, and evolution are highly variable ...
Source: Maturitas - November 1, 2023 Category: Primary Care Authors: Faustino R. P érez-López, Juan Enrique Blümel, María Soledad Vallejo, Ignacio Rodríguez, Konstantinos Tserotas, Carlos Salinas, Marcio A. Rodrigues, Claudia Rey, Eliana Ojeda, Mónica Ñañez, Carlos Miranda, Marcela López, Karen Díaz, Maribel Dext Tags: Original article Source Type: research

Nocebo-associated treatment discontinuation with subcutaneous anti-osteoporotic drugs. A systematic review and meta-analysis of placebo-arm dropouts in randomized-controlled trials
The term ‘osteoporosis care gap’ refers to the suboptimal therapeutic approach of individuals at high fracture risk that do not receive treatment either because they elude diagnosis as high-risk patients or because they are skeptical towards medication [1,2]. Several lines of evidence consider skepticism against medication as part of the communication gap between patients and health-providers that fail to address patient concerns, beliefs, preferences, or misconceptions [3–6]. As a result, patients with osteoporosis and high fracture risk that would benefit from anti-osteoporotic medication decid e not to initiate tr...
Source: Maturitas - October 31, 2023 Category: Primary Care Authors: Maria P. Yavropoulou, Maria-Iosifina Kasdagli, Polyzois Makras, Konstantina-Maria Diomatari, Athanasios D. Anastasilakis, Dimos D. Mitsikostas, Eva Kassi, Petros P. Sfikakis, Evrydiki Kravvariti Tags: Review article Source Type: research

Urinary incontinence and life-space activity/mobility additively increase the risk of incident disability among older adults
Disability, commonly defined as limitations in performing tasks needed for independence, such as activities of daily living (ADL), imposes a substantial burden on older adults and the healthcare system. Life expectancy has increased worldwide [1], and consequently, there is a need for integrated care to maintain an aging population with good health, high mental and physical function, well-being, and social engagement and productivity for a longer time. Japan has been the first country in the world to introduce a long-term care insurance system (LTCI) since 2000 [2], and all Japanese people aged 65  years and older are el...
Source: Maturitas - October 30, 2023 Category: Primary Care Authors: Kazuhei Nishimoto, Kota Tsutsumimoto, Takehiko Doi, Satoshi Kurita, Yuto Kiuchi, Hiroyuki Shimada Tags: Original article Source Type: research

High adherence to Western dietary pattern increases breast cancer risk (an EPIC-Spain study)
According to the last global cancer statistics estimates, in 2020 breast cancer (BC) was the most commonly diagnosed and the fifth leading cause of cancer mortality globally [1]. Its development has been associated with family history in first-degree relatives, height, benign breast disease, high mammographic breast density, early menarche (54  years), age at first birth over 30 years, high endogenous estrogen levels, oral contraceptive or postmenopausal hormone use, ionizing radiation exposure, high body mass index (BMI), alcohol intake, low physical activity level and not breastfeeding among other less relevant facto...
Source: Maturitas - October 28, 2023 Category: Primary Care Authors: Adela Castell ó, Miguel Rodríguez-Barranco, Virginia Lope, Marcela Guevara, Sandra Colorado-Yohar, Ane Dorronsoro, José Ramón Quirós, Carlota Castro-Espin, Carmen Sayon-Orea, Carmen Santiuste, Pilar Amiano, Cristina Lasheras, María-José Sanchez, Ma Tags: Original article Source Type: research

Exercise counters the negative impact of bed rest on executive functions in middle-aged and older adults: A proof-of-concept randomized controlled trial
Physical inactivity is common among middle-aged and older adults and is a modifiable risk factor for cognitive impairment and dementia [1]. Physical inactivity is defined as any decrease in bodily movement producing decreased energy expenditure [2]. It may occur gradually because of chronic conditions or acutely because of injury, surgery, or hospitalization. In the physical inactivity spectrum [2], complete bed rest represents an extreme level of inactivity. Even a brief period initiates a downward spiral in cognitive function in older adults [3,4]. (Source: Maturitas)
Source: Maturitas - October 17, 2023 Category: Primary Care Authors: Guilherme M. Balbim, Ryan S. Falck, Cindy K. Barha, Daria Tai, John R. Best, Guy Hajj-Boutros, Kenneth Madden, Teresa Liu-Ambrose Tags: Original Article Source Type: research

EMAS position statement: Testosterone replacement therapy in older men
People worldwide are living longer. The population aged over 60  years now surpasses 1 billion and is expected to double by 2050 [1]. Several population-based studies have documented an age-dependent, modest reduction of serum testosterone (T) concentrations in men after the fourth decade, with a decrease of about 1 % per year [2], and the T concentrations of some men will eventually drop below 8 nmol/L (250 ng/dL), the threshold agreed by most scientific societies to correspond to clinically meaningful testosterone deficiency (TD). (Source: Maturitas)
Source: Maturitas - October 14, 2023 Category: Primary Care Authors: George A. Kanakis, Riccardo Pofi, Dimitrios G. Goulis, Andrea M. Isidori, Eleni Armeni, C. Tamer Erel, Ivan Fistoni ć, Timothy Hillard, Angelica-Lindén Hirschberg, Blazej Meczekalski, Nicolás Mendoza, Alfred O. Mueck, Tommaso Simoncini, Petra Stute, Do Tags: Position statement Source Type: research

Corrigendum to "Plasma superoxide dismutase activity in relation to disability in activities of daily living and objective physical functioning among Chinese older adults" [Maturitas, Volume 161, July 2022, Pages 12 –17]
The authors regret that the affiliation for authors Xueqin Li, Xingqi Cao and Zuyun Liu were incorrectly stated in the original publication. The full and correct affiliation is restated herein. (Source: Maturitas)
Source: Maturitas - October 11, 2023 Category: Primary Care Authors: Xueqin Li, Xingqi Cao, Zhimin Ying, Guangtao Yang, Emiel O. Hoogendijk, Zuyun Liu Tags: Corrigendum Source Type: research

Scalable (low-cost) approaches for remote and personalised rehabilitation
As the ageing population increases, the need to overcome the challenges of reduced or poor mobility among older adults is profound. That is because walking is a fundamental activity of daily living (ADL) and is often impeded in older adults due to a myriad of age-related conditions such as stroke, Parkinson's disease (PD), and frailty. Accordingly, those conditions impact the quality of life by causing a high risk of falls and reduced independence. Moreover, psychological health may be compromised which can lead to depression and fear (of falling), creating a snowballing effect for even poorer mobility. (Source: Maturitas)
Source: Maturitas - October 8, 2023 Category: Primary Care Authors: Conor Wall, Alan Godfrey Tags: Editorial Source Type: research

Menopausal symptoms in midlife Singaporean women: Prevalence rates and associated factors from the Integrated Women's Health Programme (IWHP)
By 2025, 1.1 billion of the world's women will be postmenopausal [1]. Studying menopausal symptoms is vital for understanding their impact on relationships, work, and health [2,3]. Menopausal symptom prevalence is well-described in Caucasian populations [4,5]. Although a number of studies on vasomotor symptoms and other aspects of menopausal symptomatology in Asian women have been published [6], few have examined the association between menopausal symptoms and its constituent domains with health outcomes such as disability and muscle function. (Source: Maturitas)
Source: Maturitas - October 6, 2023 Category: Primary Care Authors: Susan Logan, Beverly Wen Xin Wong, Joelle Hwee Inn Tan, Michael S. Kramer, Eu-Leong Yong Tags: Original article Source Type: research

Editorial board
(Source: Maturitas)
Source: Maturitas - September 27, 2023 Category: Primary Care Source Type: research

Genes and environment: An old pair in a new era
According to Darwin, evolution is based on four processes: (i) there is variation in the population; (ii) this variation is heritable; (iii) there is competition between progeny with and without the variant(s); (iv) survival of the species and inheritance of the variation(s) are associated with successful outcome of the competition; these are not random processes [1]. In the Darwinian theory, in other words, the environment plays the role of an influencer, with natural selection being the ultimate shaper of future genetics, as Huxley proposed in his “Modern Evolutionary Synthesis”, but a full understanding of evolution...
Source: Maturitas - September 25, 2023 Category: Primary Care Authors: Constantine A. Stratakis Tags: Opinion paper Source Type: research

Influence of type of household on prognosis at one year in patients ≥65 years attending hospital emergency departments in Spain. The EDEN-6 study
The aging of the population is a worldwide phenomenon. The percentage of the population  ≥ 65 years has increased and will rise in the next few years [1]. In Europe, this population is expected to increase from 90.5 million in 2019 to 129.8 million by 2050 [2]. Elderly patients have a greater number of comorbidities and functional and cognitive limitations. As a result, they are n ot only more likely to become ill but also have atypical complaints and specific syndromes associated with frailty [3]. (Source: Maturitas)
Source: Maturitas - September 21, 2023 Category: Primary Care Authors: Aitor Alqu ézar-Arbé, Gina I. Osorio, Javier Jacob, Eric Jorge García-Lamberechts, Pascual Piñera Salmerón, Pere Llorens, Guillermo Burillo-Putze, Angela Cobos Requena, Adriana Gil, Cesáreo Fernández, Sira Aguiló, Sònia Jiménez, Beatriz Escudero Tags: Original article Source Type: research

Influence of type of household on prognosis at one year in patients ≥65 years attending hospital emergency departments in Spain. The EDEN-6 study
The aging of the population is a worldwide phenomenon. The percentage of the population  ≥ 65 years has increased and will rise in the next few years [1]. In Europe, this population is expected to increase from 90.5 million in 2019 to 129.8 million by 2050 [2]. Elderly patients have a greater number of comorbidities and functional and cognitive limitations. As a result, they ar e not only more likely to become ill but also have atypical complaints and specific syndromes associated with frailty [3]. (Source: Maturitas)
Source: Maturitas - September 21, 2023 Category: Primary Care Authors: Aitor Alqu ézar-Arbé, Gina I. Osorio, Javier Jacob, Eric Jorge García-Lamberechts, Pascual Piñera Salmerón, Pere Llorens, Guillermo Burillo-Putze, Angela Cobos Requena, Adriana Gil, Cesáreo Fernández, Sira Aguiló, Sònia Jiménez, Beatriz Escudero Tags: Original article Source Type: research

Association of circulating vitamin D and omega 3 fatty acid with all-cause mortality in patients with rheumatoid arthritis: A large population-based cohort study
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects around 0.46  % of the global population [1]. It is characterized by painful joint inflammation that can lead to cartilage and bone damage, joint dysfunction, disability, and a reduced quality of life. The etiology of RA remains not fully elucidated but is thought to result from a combination of genetic predis position, environmental factors, and immune dysregulation [2]. Despite recent advances in therapy, a cure for RA remains elusive and more effective treatments continue to be explored [3,4]. (Source: Maturitas)
Source: Maturitas - September 15, 2023 Category: Primary Care Authors: Siyu Chen, Shiqi Chen, Zhijian Zhao, Xueqing Cao, Zhangling Chen, Jun Lin Tags: Original Article Source Type: research

Long-term life satisfaction in ageing women with work disability due to mental and musculoskeletal disorders
The World Health Organization (WHO) has defined heathy ageing as a process of developing and maintaining functional ability, enabling physical, mental and social wellbeing [1]. Thus, there is a need for a realistic and multifaceted view of healthy ageing – covering both its objective and subjective dimensions – to understand and optimize overall health and wellbeing among ageing adults. (Source: Maturitas)
Source: Maturitas - September 15, 2023 Category: Primary Care Authors: J. Heikkinen, R.J. Honkanen, S.E. Quirk, L.J. Williams, H. Koivumaa-Honkanen Tags: Original Article Source Type: research