The effect of genetic variation in estrogen transportation and metabolism on the severity of menopause symptoms: A study from the RIGHT 10K cohort
Hot flashes and night sweats (vasomotor symptoms, VMS) are the most common symptom of the menopause transition, affecting up to three-fourths of women in this phase of life [1]. They are severe in intensity in about one-third of affected women, and can significantly impact mood, sleep, sexual function and quality of life [2 –5]. In addition to these more immediate consequences of VMS, there is increasing recognition that VMS are predictive of disease risk in women, including risk of cardiovascular disease [1,6], low bone density and fractures [7,8], and breast cancer [9]. (Source: Maturitas)
Source: Maturitas - August 16, 2023 Category: Primary Care Authors: Ekta Kapoor, Stephanie S. Faubion, Carol L. Kuhle, Juliana M. Kling, Virginia M. Miller, Shawn Fokken, Kristin C. Mara, Ann M. Moyer Tags: Original article Source Type: research
The invaluable contributions of clinical pharmacy to geriatric medicine
As the field of geriatric medicine continues to evolve, the importance of comprehensive and personalized care for elderly patients becomes increasingly evident. In this context, clinical pharmacy has emerged as a vital component in optimizing medication and improving patient outcomes. We detail here some of the significant contributions of clinical pharmacy to the field of geriatric medicine. (Source: Maturitas)
Source: Maturitas - August 16, 2023 Category: Primary Care Authors: Mathieu Corvaisier, C édric Annweiler Tags: Editorial Source Type: research
Energy drink consumption in nurses: Is high-stress work relevant to the adoption of poor drinking habits?
Recent research has highlighted high consumption of caffeine-rich beverages by healthcare workers. [1,2] This mainly concerns the consumption of energy drinks (EDs) during working hours, especially at night. (Source: Maturitas)
Source: Maturitas - August 16, 2023 Category: Primary Care Authors: Anna Vittoria Mattioli, Francesca Coppi, Alberto Farinetti Tags: Letter to the editor Source Type: research
Associations between low sex hormone concentrations and depression in older women: An observational study
Depression is the most common mental illness world-wide, and has been reported as more prevalent in women than in men [1]. It has been suggested that relative sex hormone insufficiency, notably lower testosterone concentrations in postmenopausal women compared with men [2], may contribute to a greater likelihood of depression. A systematic review of depression in the elderly indicated the point prevalence of depression to be between 4.0 % and 10.3 % for women over 75 years [3]. Women of this age are approximately 50 % more likely to be affected than men [3]. (Source: Maturitas)
Source: Maturitas - August 3, 2023 Category: Primary Care Authors: Rakibul M. Islam, Robin J. Bell, Michael Berk, David J. Handelsman, John J. McNeil, Rory Wolfe, Robyn L. Woods, Susan R. Davis Tags: Original article Source Type: research
Intrinsic capacity and risk of death: Focus on the impact of using different diagnostic criteria for the nutritional domain
Intrinsic capacity (IC) is a multidimensional construct, defined as “the composite of all the physical and mental capacities of an individual”, launched by the World Health Organization (WHO) in the World Report on Ageing and Health in 2016 [1,2]. An unsatisfactory IC is associated to adverse health outcomes and higher mortality-risk [3–5] and has been propose d as outcome indicator of healthy ageing and Public Health actions by the WHO Integrated Care for Older People (ICOPE) Guidelines [6,7]. Joining forces with the United Nations, the WHO has proclaimed the Decade of Healthy Ageing 2021–2030. (Source: Maturitas)
Source: Maturitas - August 3, 2023 Category: Primary Care Authors: D. Sanchez-Rodriguez, C. Demonceau, O. Bruy ère, E. Cavalier, J.-Y. Reginster, C. Beaudart Tags: Original article Source Type: research
Editorial board
(Source: Maturitas)
Source: Maturitas - August 2, 2023 Category: Primary Care Source Type: research
#Menopause: Examining the frequency of communications about menopause on twitter between 2014 and 2022
Recent attention has turned to social media and the menopause. For example, a study of posts on the social media platform Instagram [1] found images, video and/or text about menopause that included advertisements (48 %), advice on self-care (47 %), and physical health (44 %). Twitter is a popular social media platform, with an estimated 556 million active users [2]; it provides a microblogging and social network service where users can communicate via “tweet” messages with a 280-character limit. (Source: Maturitas)
Source: Maturitas - July 28, 2023 Category: Primary Care Authors: Myra S. Hunter, Mahmoud El-Haj, Eleanor Thorne, Amanda Griffiths, Claire Hardy Tags: Short communication Source Type: research
The sensitivity and specificity of the WHO's ICOPE screening tool, and the prevalence of loss of intrinsic capacity in older adults: A scoping review
The World Health Organization (WHO) published, in 2017, the Integrated Care for Older People (ICOPE) Guidelines, aiming at the reduction of care dependency through the promotion of healthy aging and the maintenance of older people's functional status [1]. The ICOPE approach proposes a multi-step pathway, starting with the screening of older adults for capacity impairments (Step 1), followed by an in-depth assessment of positive-screened individuals (Step 2), implementation of person-centered interventions to promote, rehabilitate and maintain functional ability (Step 3), and a long-term care follow-up framework (Step 4). (Source: Maturitas)
Source: Maturitas - July 28, 2023 Category: Primary Care Authors: Vitor Pelegrim de Oliveira, Eduardo Ferriolli, Roberto Alves Louren ço, Emmanuel González-Bautista, Philipe de Souto Barreto, Renato Gorga Bandeira de Mello Tags: Review article Source Type: research
Association between endometriosis and risk of type 2 diabetes: Results from the prospective E3N cohort
Endometriosis is defined by the presence of endometrial-like tissue outside the uterus. It is a chronic, inflammatory, and estrogen-dependent disorder affecting 10 % of fertile age women [1,2]. The disease is associated with signs and symptoms such as chronic pelvic pain and infertility [3]. Despite its high incidence and heavy burden on women's quality of life [4], the etiology of endometriosis is unknown. The early age at menarche, short menstrual cycle l ength, and lean body size [2] are the most consistently reported risk markers. (Source: Maturitas)
Source: Maturitas - July 27, 2023 Category: Primary Care Authors: Patricia Vaduva, Nasser Laouali, Guy Fagherazzi, Amandine Gelot, Fabrice Bonnet, Marina Kvaskoff Tags: Original article Source Type: research
Publisher ’s note
Within the publishing industry, article numbering has emerged as an easy and efficient way to cite journal articles. Article numbering has already been successfully rolled out to more than 1600 Elsevier journals, and has been well received by the academic community. Based on that positive feedback, we are now pleased to introduce article numbering to Maturitas from issue 175. (Source: Maturitas)
Source: Maturitas - July 26, 2023 Category: Primary Care Source Type: research
Barriers to and facilitators of a healthy lifestyle for patients with gynecological cancer: a systematic review of qualitative and quantitative research with healthcare providers and patients
Gynecological malignancies account for 15 % of all cancers in women, which translates to nearly 1.4 million women being diagnosed annually worldwide [1]. The development of gynecological malignancies can be partly attributed to lifestyle factors such as obesity, smoking, physical inactivity [2] and an unhealthy diet [3,4]. Obesity is a k ey issue and associated with increased risk of gynecological malignancies and present in 45–70 % of endometrial, and 30 % of ovarian cancer patients [1,5–8]. (Source: Maturitas)
Source: Maturitas - July 21, 2023 Category: Primary Care Authors: Bo Brummel, Cindy van Heumen, Anke Smits, Manon van den Berg, Nicole P.M. Ezendam, Johanna M.A. Pijnenborg, Marian A.E. de van der Schueren, Shelley A. Wilkinson, Barbara S. van der Meij Tags: Review article Source Type: research
Within-person changes in reproductive hormones and cognition in the menopause transition
Approximately two-thirds of women experience cognitive deficits such as forgetfulness, fuzzy thinking, poor working memory, and poor concentration during the menopause transition [1,2]. Hormonal changes, namely increased fluctuations in the reproductive hormone 17- β estradiol, may contribute to these deficits [3]. Estradiol receptors populate the human brain, including areas that are critical for language, attention, and executive function [4]; exogenous estradiol also has beneficial effects on working memory, executive function, language, and attention [5,6 ]. (Source: Maturitas)
Source: Maturitas - July 21, 2023 Category: Primary Care Authors: Julia A. Grummisch, Laurie Sykes Tottenham, Jennifer L. Gordon Tags: Original article Source Type: research
Environment and menopause: The best time for action is now
The function of the hypothalamus-pituitary-gonadal (HPG) axis is based on the pulsatile secretion of the hypothalamic gonadotrophin regulating hormone, which controls the secretion of pituitary gonadotrophins; the latter interact with ovarian receptors to regulate sex hormone production. On the other hand, estrogenic receptors in the hypothalamic nucleus regulate the HPG axis [1,2]. Exogenous or endocrine-disrupting chemicals (EDCs) can unintentionally disrupt this intricate communication system, leading to adverse health effects. (Source: Maturitas)
Source: Maturitas - July 20, 2023 Category: Primary Care Authors: Eleni Armeni Tags: Editorial Source Type: research
An evaluation of demographic characteristics and workplace experiences of UK employees using an employer-provided menopause app
Workplace participation among women has increased steeply in the last decades. In the UK, the Office for National Statistics report that the percentage of women in employment has risen from 52.7 % in 1971 to 71.9 % in 2021 [1]. Among those aged between 50 and 65, 19.6 % more women are in paid employment in November 2022 than in March 1992. Together with an aging population and a higher retirement age, more women than ever will be undergoing the menopausal transition while in work. Th e menopause, marked by the cessation of menstruation usually occurs between the age of 45 and 55, and is often accompanied by a range ...
Source: Maturitas - July 20, 2023 Category: Primary Care Authors: Thea S. Schei, Kathy Abernethy Tags: Original article Source Type: research
New perspectives on frailty in light of the Global Leadership Initiative on Malnutrition, the Global Leadership Initiative on Sarcopenia, and the WHO's concept of intrinsic capacity: A narrative review
The World Health Organization (WHO) defines frailty as an increased vulnerability to health problems, compromising the ability of older individuals to cope with daily or acute stressors [1]. Frailty is strongly linked to chronological age, chronic diseases, and negative outcomes [2], and it significantly predicts all-cause mortality in community-dwelling adults. (Source: Maturitas)
Source: Maturitas - July 19, 2023 Category: Primary Care Authors: Elena Mu ñoz-Redondo, Andrea Morgado-Pérez, María José Pérez-Sáez, Julio Pascual, Marta Tejero-Sánchez, Yulibeth G. Curbelo, Marc Terradellas-Fernández, Delky Meza-Valderrama, Olga Vázquez-Ibar, Cédric Annweiler, Dolores Sánchez-Rodríguez, Est Tags: Review article Source Type: research
