Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys ( < em > Saimiri sciureus < /em > )
J Immunol Res. 2024 Mar 25;2024:8215195. doi: 10.1155/2024/8215195. eCollection 2024.ABSTRACTNonhuman primates are an important experimental model for the development of targeted biological therapeutics because of their immunological closeness to humans. However, there are very few antibody reagents relevant for delineating the different immune cell subsets based on nonhuman primate antigens directly or with cross-reactivity to those in humans. Here, we report specific expression of HLA-DR, PD-1, and CD123 on different circulating immune cell subsets in the peripheral blood that included T cells (CD3+), T cells subsets (CD...
Source: Journal of Immunology Research - April 3, 2024 Category: Allergy & Immunology Authors: Bharti P Nehete Ashley DeLise Pramod N Nehete Source Type: research
SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - March 29, 2024 Category: Allergy & Immunology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research
An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence
J Immunol Res. 2024 Mar 14;2024:9307906. doi: 10.1155/2024/9307906. eCollection 2024.ABSTRACTA decline in immune response, exhibited in the form of immunosenescence and inflammaging, is an age-associated disturbance of the immune system known to predispose the elderly to a greater susceptibility to infection and poor vaccine response. Polysaccharides and polyphenols from botanicals are known for their immune modulation effects. Here we evaluated a standardized mushroom-based composition, UP360, from Aloe barbadensis, Poria cocos, and Rosmarinus officinalis, as a natural nutritional supplement for a balanced immune response...
Source: Journal of Immunology Research - March 22, 2024 Category: Allergy & Immunology Authors: Mesfin Yimam Teresa Horm Alexandria O'Neal Ping Jiao Mei Hong Qi Jia Source Type: research
