Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto's Thyroiditis
J Immunol Res. 2023 Aug 25;2023:5221658. doi: 10.1155/2023/5221658. eCollection 2023.ABSTRACTT helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto's thyroiditis (HT). Changes in the serum level of autoantibodies to cytokines, which may be able to modulate their availability and actions have been described in several autoimmune disorders. Yet, no data are available on anti-cytokine autoantibodies either during early pregnancy or in patients with HT. The aim of the study was to measure autoantibodies to inflammatory-, Th1- and Th22-cytokines in seru...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Szabina Erd ő-Bonyár Di ána Simon Anna Bajnok Jasper N örenberg T ímea Serény-Litvai Ákos Várnagy K álmán Kovács Eszter Hantosi Emese Mez ősi T ímea Berki Source Type: research
Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NF < em > κ < /em > B Signal in Mice
J Immunol Res. 2023 Aug 24;2023:1116841. doi: 10.1155/2023/1116841. eCollection 2023.ABSTRACTAcetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in severe cases by triggering an inflammatory response and oxidative stress. Sesamin has been reported to possess anti-inflammatory and antioxidant actions in several animal disease models. In the present study, the effects and mechanisms of sesamin on APAP-induced acute liver injury (ALI) were explored. The results showed that pretreatment with sesamin significantly alleviated APAP-induced ALI, as indicated by decreased serum aminotransferase a...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Hui Du Shiwen Tong Ge Kuang Xia Gong Ningman Jiang Xian Yang Hao Liu Nana Li Yao Xie Yang Xiang Jiashi Guo Zhenhan Li Yinglin Yuan Shengwang Wu Jingyuan Wan Source Type: research
Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto's Thyroiditis
J Immunol Res. 2023 Aug 25;2023:5221658. doi: 10.1155/2023/5221658. eCollection 2023.ABSTRACTT helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto's thyroiditis (HT). Changes in the serum level of autoantibodies to cytokines, which may be able to modulate their availability and actions have been described in several autoimmune disorders. Yet, no data are available on anti-cytokine autoantibodies either during early pregnancy or in patients with HT. The aim of the study was to measure autoantibodies to inflammatory-, Th1- and Th22-cytokines in seru...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Szabina Erd ő-Bonyár Di ána Simon Anna Bajnok Jasper N örenberg T ímea Serény-Litvai Ákos Várnagy K álmán Kovács Eszter Hantosi Emese Mez ősi T ímea Berki Source Type: research
Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NF < em > κ < /em > B Signal in Mice
J Immunol Res. 2023 Aug 24;2023:1116841. doi: 10.1155/2023/1116841. eCollection 2023.ABSTRACTAcetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in severe cases by triggering an inflammatory response and oxidative stress. Sesamin has been reported to possess anti-inflammatory and antioxidant actions in several animal disease models. In the present study, the effects and mechanisms of sesamin on APAP-induced acute liver injury (ALI) were explored. The results showed that pretreatment with sesamin significantly alleviated APAP-induced ALI, as indicated by decreased serum aminotransferase a...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Hui Du Shiwen Tong Ge Kuang Xia Gong Ningman Jiang Xian Yang Hao Liu Nana Li Yao Xie Yang Xiang Jiashi Guo Zhenhan Li Yinglin Yuan Shengwang Wu Jingyuan Wan Source Type: research
Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto's Thyroiditis
J Immunol Res. 2023 Aug 25;2023:5221658. doi: 10.1155/2023/5221658. eCollection 2023.ABSTRACTT helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto's thyroiditis (HT). Changes in the serum level of autoantibodies to cytokines, which may be able to modulate their availability and actions have been described in several autoimmune disorders. Yet, no data are available on anti-cytokine autoantibodies either during early pregnancy or in patients with HT. The aim of the study was to measure autoantibodies to inflammatory-, Th1- and Th22-cytokines in seru...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Szabina Erd ő-Bonyár Di ána Simon Anna Bajnok Jasper N örenberg T ímea Serény-Litvai Ákos Várnagy K álmán Kovács Eszter Hantosi Emese Mez ősi T ímea Berki Source Type: research
Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NF < em > κ < /em > B Signal in Mice
J Immunol Res. 2023 Aug 24;2023:1116841. doi: 10.1155/2023/1116841. eCollection 2023.ABSTRACTAcetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in severe cases by triggering an inflammatory response and oxidative stress. Sesamin has been reported to possess anti-inflammatory and antioxidant actions in several animal disease models. In the present study, the effects and mechanisms of sesamin on APAP-induced acute liver injury (ALI) were explored. The results showed that pretreatment with sesamin significantly alleviated APAP-induced ALI, as indicated by decreased serum aminotransferase a...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Hui Du Shiwen Tong Ge Kuang Xia Gong Ningman Jiang Xian Yang Hao Liu Nana Li Yao Xie Yang Xiang Jiashi Guo Zhenhan Li Yinglin Yuan Shengwang Wu Jingyuan Wan Source Type: research
Physiological Changes in the Levels of Anti-Cytokine Autoantibodies in Early Pregnancy Are Missing in Pregnant Women with Hashimoto's Thyroiditis
J Immunol Res. 2023 Aug 25;2023:5221658. doi: 10.1155/2023/5221658. eCollection 2023.ABSTRACTT helper type 1 (Th1) and inflammatory cytokines play essential roles in early pregnancy and also in the pathogenesis of Hashimoto's thyroiditis (HT). Changes in the serum level of autoantibodies to cytokines, which may be able to modulate their availability and actions have been described in several autoimmune disorders. Yet, no data are available on anti-cytokine autoantibodies either during early pregnancy or in patients with HT. The aim of the study was to measure autoantibodies to inflammatory-, Th1- and Th22-cytokines in seru...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Szabina Erd ő-Bonyár Di ána Simon Anna Bajnok Jasper N örenberg T ímea Serény-Litvai Ákos Várnagy K álmán Kovács Eszter Hantosi Emese Mez ősi T ímea Berki Source Type: research
Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NF < em > κ < /em > B Signal in Mice
J Immunol Res. 2023 Aug 24;2023:1116841. doi: 10.1155/2023/1116841. eCollection 2023.ABSTRACTAcetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in severe cases by triggering an inflammatory response and oxidative stress. Sesamin has been reported to possess anti-inflammatory and antioxidant actions in several animal disease models. In the present study, the effects and mechanisms of sesamin on APAP-induced acute liver injury (ALI) were explored. The results showed that pretreatment with sesamin significantly alleviated APAP-induced ALI, as indicated by decreased serum aminotransferase a...
Source: Journal of Immunology Research - September 4, 2023 Category: Allergy & Immunology Authors: Hui Du Shiwen Tong Ge Kuang Xia Gong Ningman Jiang Xian Yang Hao Liu Nana Li Yao Xie Yang Xiang Jiashi Guo Zhenhan Li Yinglin Yuan Shengwang Wu Jingyuan Wan Source Type: research
The Important Role of Interleukin-2 in COVID-19
J Immunol Res. 2023 Aug 22;2023:7097329. doi: 10.1155/2023/7097329. eCollection 2023.ABSTRACTThere is controversial literature about the effects of the interleukin-2 (IL-2) cytokine family in COVID-19 pathogenesis and immunity. So we aimed to identify the potential in the role of the IL-2 family in COVID-19. A narrative review search was done through online databases, including PubMed, Scopus, and Web of Science. The search deadline was up to December 2022. We applied no time limits for the searching strategy. After retrieving articles from the databases, the authors summarized the data into two data extraction tables. The...
Source: Journal of Immunology Research - August 31, 2023 Category: Allergy & Immunology Authors: Leila Ghanbari Naeini Laleh Abbasi Farzaneh Karimi Pajman Kokabian Fahimeh Abdi Abyaneh Delaram Naderi Source Type: research
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats
In conclusion, microglia are key mediators of the inflammatory response and exhibit continuous phenotypic polarization 7-21 days after HI-induced WMD. This finding can potentially lead to a new treatment regimen targeting the phenotypic polarization of microglia early after HI-induced brain injury.PMID:37636861 | PMC:PMC10460280 | DOI:10.1155/2023/5149306 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - August 28, 2023 Category: Allergy & Immunology Authors: Liu Yang Yajun Zhang Xuefei Yu Danni Li Na Liu Xindong Xue Jianhua Fu Source Type: research
Retracted: Mutational Screening of Skeletal Genes in 14 Chinese Children with Osteogenesis Imperfecta Using Targeted Sequencing
J Immunol Res. 2023 Aug 16;2023:9782082. doi: 10.1155/2023/9782082. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/5068523.].PMID:37621922 | PMC:PMC10447018 | DOI:10.1155/2023/9782082 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - August 25, 2023 Category: Allergy & Immunology Authors: Journal Of Immunology Research Source Type: research
