Secular trends in blood pressure trajectories in Chinese children and adolescents: the impact of changing physical growth
Background:
Globally, 80% of cardiovascular disease (CVD) occur in low-income /middle-income countries. High blood pressure (BP), a major risk factor for CVD, has its origins in early-life. We investigated how age trajectories of BP (childhood to late-adolescence) have changed recently in China and the mediating roles of physical growth.
Methods:
Using the longitudinal data on 3785 children from the China Health and Nutrition Survey 1991–2015, we estimated mean BP trajectories (7–18 years) for cohorts born in 1981–1985, 1986–1990, 1991–1995 and 1996–2000 using random effect models. Models were adjust...
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Influencing factors of supernormal vascular aging in Chinese population
Conclusion:
This study investigated the characteristics of the population with SUPERNOVA and the factors influencing it, which provided a basis for different populations to take preventive measures to slow down the process of vascular aging. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Association between oral health and cardiovascular outcomes in patients with hypertension: a nationwide cohort study
Conclusion:
Our study demonstrated that multiple dental caries were related to the risk of cardiovascular diseases in hypertensive patients. Better oral hygiene may attenuate the risk of cardiovascular events in hypertensive patients. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Sex-specific associations of brachial–ankle pulse wave velocity with adverse cardiac remodeling and long-term cardiovascular outcome
This study aimed to investigate the sex-specific association of brachial–ankle pulse wave velocity (baPWV) with adverse cardiac remodeling and cardiovascular outcome.
Method:
We studied 11 767 patients (57.6% men) with cardiovascular risk factors, whose baPWV was measured. The primary endpoint was composite cardiovascular events. Restricted cubic spline (RCS) analyses were performed to delineate the association of baPWV with echocardiography parameters and risks of cardiovascular events.
Results:
RCS curves showed that structural/functional echocardiography parameters gradually worsened with increasing ba...
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Sex differences in ambulatory blood pressure levels, control, and phenotypes of hypertension in kidney transplant recipients
Conclusion:
BP levels, hypertension prevalence and control are similar by office criteria but significantly different by ABPM criteria between male and female KTRs. Worse ambulatory BP control in male compared with female KTRs may interfere with renal and cardiovascular outcomes. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Urine N-acetyl-Ser-Asp-Lys-Pro measurement as a versatile biomarker to assess adherence to angiotensin-converting enzyme inhibitors
Conclusion:
Overall, spot urine AcSDKP measurement by LC-MS/MS is a reliable marker of the intake of ACEI treatment and could substitute ACEI metabolites detection. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Central-to-peripheral stiffness gradients determine diastolic pressure and flow fluctuation waveforms: time domain analysis of femoral artery pulse
Objective:
Blood pressure fluctuates during diastole to create a dicrotic wave but the mechanistic origin remains poorly understood. We sought to investigate the characteristics and determinants of diastolic pressure and flow fluctuations with a focus on stiffness gradients between the central aorta and peripheral arteries.
Methods:
Using applanation tonometry and duplex ultrasound, pulse waveforms were recorded on the femoral artery in 592 patients (age: 55 ± 14 years) to estimate the diastolic pressure fluctuation as a residual wave against the mono-exponential decay and the diastolic flow fluctuation a...
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Febuxostat ameliorates high salt intake-induced hypertension and renal damage in Dahl salt-sensitive rats
Conclusion:
Febuxostat ameliorates high salt diet-induced hypertension and renal damage with a reduction of renal oxidative stress in Dahl salt-sensitive rats. The antihypertensive effect of febuxostat may be mediated in part by diuretic and natriuretic action. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Moderate to severe obstructive sleep apnea is independently associated with inter-arm systolic blood pressure difference: Tokyo Sleep Heart Study
Objective:
Obstructive sleep apnea (OSA) is recognized as an independent risk factor for cardiovascular disease. On the other hand, inter-arm systolic blood pressure difference (IAD), inter-ankle systolic blood pressure difference (IAND), and ankle-brachial index (ABI) are all known predictors of cardiovascular events. The aim of the present study was to investigate the association between OSA and four-limb blood pressure differences.
Methods:
We conducted this cross-sectional study in a large sleep cohort from Tokyo Sleep Heart Study. In 2643 consecutive patients who visited our sleep clinic for polysomnography...
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Circulating miR-3656 induces human umbilical vein endothelial cell injury by targeting eNOS and ADAMTS13: a novel biomarker for hypertension
Conclusion:
MiR-3656 is a potential biomarker for hypertension. MiR-3656 is involved in endothelial cellular injury implicated in hypertension by targeting eNOS and ADAMTS13. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Peak exercise SBP and future risk of cardiovascular disease and mortality
Conclusion:
Low, but not high, PeakSBP was associated with an increased risk of mortality and future cardiovascular disease. Using reference standards for PeakSBP could facilitate clinical risk stratification across patients of varying sex, age and exercise capacity. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Dietary sodium intake and sodium load is associated with arterial stiffness in children and young adults
Objective:
The aim of this study was to examine the association of sodium intake (g/day) and sodium load (Na-L; mg/kcal/day) on arterial stiffness in youth.
Methods:
A cross-sectional analysis of 723 youth enrolled in a study evaluating the cardiovascular effects of obesity and type 2 diabetes mellitus (T2DM). Three measures of arterial stiffness were evaluated: brachial distensibility (BrachD), carotid-femoral pulse wave velocity (PWVcf) and augmentation index (AIx). Three-day diet histories yielded mean daily sodium and calorie intake. Youth were divided into Na-L tertiles: Low (≤1.67 mg/kcal per day); Med...
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
C-reactive protein and hypertension among Ghanaian migrants and their homeland counterparts: the Research on Obesity and Diabetes among African Migrants study
Conclusion:
Our findings show an association between CRP and HTN among Ghanaian migrants and urban-Ghanaian women, however, this was largely explained by conventional risk factors. Thus, prevention of conventional risk factors, in particular obesity, may help to reduce the potentially low-grade inflammatory mechanism underlying HTN. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Incidence and correlates of high blood pressure from childhood to adulthood: the Birth to Twenty study
Conclusion:
Maternal parity and relative weight gain were determinants for incident high blood pressure in urban black South African children and adolescents. To reduce the high incidence and the disease burden of high BP, national programs should focus on promoting healthy lifestyle in early stages of life to prevent rapid weight gain and later cardiovascular disease risk. Further research is required to investigate whether incident high BP in childhood predict clinical outcomes in adulthood. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
A nomogram integrating non-ECG factors with ECG to screen left ventricular hypertrophy among hypertensive patients from northern China
Conclusion:
The integrated nomogram is a convenient and reliable tool that enables early identification of hypertensive patients at high odds of LVH and can assist clinicians in their decision-making. (Source: Journal of Hypertension)
Source: Journal of Hypertension - January 16, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
