Prevalence and renal prognosis of left ventricular diastolic dysfunction in non-dialysis chronic kidney disease patients with preserved systolic function
Conclusion:
In ND-CKD population, LV diastolic dysfunction is less frequent than previously described and acts as independent predictor of CKD progression. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Consequences of hyperandrogenemia during pregnancy in female offspring: attenuated response to angiotensin II
Conclusion:
Taken together, these data suggest that female HAF offspring are protected from developing hypertension, but may be at risk for renal injury with aging. Future studies are necessary to determine whether adult and postmenopausal offspring of PCOS women are at increased risk for cardiovascular dysfunction.
Graphical abstract:http://links.lww.com/HJH/B820 (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
The association of uric acid with mortality modifies at old age: data from the uric acid right for heart health (URRAH) study
Conclusions:
These results confirmed the predictive role of SUA for all-cause and CV mortality in older adults, while revealing considerable age-related differences. Mortality risk increased at higher SUA levels in participants aged 65–74, with a prognostic threshold of 4.8 mg/dl. The relationship between SUA and mortality was J-shaped in oldest participants. Large interventional studies are needed to clarify the benefits and possible risks of urate-lowering treatments in older adults. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Comparison of the mean of the first two blood pressure readings with the overall mean of three readings on a single occasion
Objective:
Guidelines differed on the required number of blood pressure (BP) readings for accurate BP assessment. We, therefore, compared the mean of the first two BP readings with the overall mean of three readings in the diagnosis of hypertension.
Methods:
BP was measured three times consecutively with a 1 min interval using a validated automated electronic BP monitor in volunteers aged at least 18 years. The mean of the first and second BP readings was compared with the mean of the three blood pressure readings for the diagnostic accuracy of hypertension.
Results:
Of the 77 520 study participants...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Association between DBP and major adverse cardiovascular events in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
Background:
In patients with stable coronary artery disease, low DBP is associated with an increased risk of myocardial infarction and cardiovascular death, but its association with clinical outcomes in patients with acute myocardial infarction undergoing percutaneous coronary intervention (PCI) is unknown.
Methods:
Consecutive patients with ST-segment elevation myocardial infarction (STEMI) undergoing PCI from January 2010 to June 2016 were enrolled. The patients were divided into five groups according to the quintiles of DBP at admission. The primary outcome was in-hospital major adverse cardiovascular events ...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Association between post-traumatic stress disorder and hypertension in Congolese exposed to violence: a case–control study
Background:
Numerous risk factors have been involved in the pathogenesis of hypertension. The contribution of psychological factors, including post-traumatic stress disorder, remains largely underexplored, despite their potential role in hypertension.
Objectives:
We compared the prevalence of trauma, post-traumatic stress and other psychological disorders between hypertensive and normotensive patients from Bukavu (Democratic Republic of Congo), a 25-year war-exposed city.
Methods and measures:
In this case–control study, we assessed past traumatic events with the Stressful-Events-Scale, post-traumatic s...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Rho kinase inhibition ameliorates vascular remodeling and blood pressure elevations in a rat model of apatinib-induced hypertension
Conclusion:
These findings suggest that activation of the RhoA/ROCK signaling pathway could be the underlying mechanism of apatinib-induced hypertension, while ROCK inhibitor have potential therapeutic value. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Antecedent use of renin-angiotensin system inhibitors is associated with reduced mortality in elderly hypertensive Covid-19 patients
Conclusion:
In the population of over-68 hypertensive Covid-19 patients, antecedent use of ACEIs or ARBs was associated with a lower all-cause mortality, whether in-hospital or shortly after discharge, compared with no-antecedent-use of RASIs. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Carotid–femoral pulse wave velocity acquisition methods and their associations with cardiovascular risk factors and subclinical biomarkers of vascular health
Background:
Different methods to measure carotid–femoral pulse wave velocity (CFPWV) may affect the measurements obtained and influence the association between CFPWV, cardiovascular risk factors and biomarkers of subclinical vascular health. The estimation of distance between the carotid and femoral artery measurement sites (the arterial path length) is particularly problematic.
Method:
We determined if CFPWV and equation-based estimates of CFPWV were influenced by arterial path length and if this affected the association of CFPWV with cardiovascular risk factors and subclinical vascular biomarkers. The CFPWV ...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Association of urinary angiotensinogen with renal arteriolar remodeling in chronic kidney disease
Conclusion:
In patients with CKD, renal RAS might be associated with renal arteriolar remodeling and future decline in eGFR, independent of potential risk factors. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
The counter-regulatory arm of the renin-angiotensin system and COVID-19: insights from Gitelman's and Bartter's syndromes
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: EDITORIAL Source Type: research
Effect of long-term antihypertensive therapy on myocardial strain: a meta-analysis
Aim:
Evidence on the impact of blood pressure (BP)-lowering drugs on left ventricular (LV) mechanics in hypertension is still limited. We performed a meta-analysis of speckle-tracking echocardiographic studies in order to provide a new piece of information on this topic.
Methods:
The PubMed, OVID-MEDLINE, and Cochrane library databases were analysed to search for articles published from the inception up to 31 October 2021. Studies were identified by using MeSH terms and crossing the following search items: ‘myocardial strain’, ‘left ventricular mechanics’, ‘speckle tracking echocardiography’, ‘syst...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: REVIEW Source Type: research
Initial combination therapy for hypertension in patients of African ancestry: a systematic review and meta-analysis
We systematically reviewed randomized controlled trials (RCTs) that consider the effect of initial dual antihypertensive combination treatment on blood pressure (BP), morbidity, or mortality in hypertensive African ancestry adults, using the methodology of the Cochrane Collaboration. Main outcomes were difference in means (continuous data) and risk ratio (dichotomous data).
We retrieved 1728 reports yielding 13 RCTs of 4 weeks to 3 years duration (median 8 weeks) in 3843 patients. Systolic BP was significantly higher on β-adrenergic blocker vs. other combinations, 3.80 [0.82;6.78] mmHg, but comparable for other c...
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: REVIEW Source Type: research
Basal septal hypertrophy: extremely sensitive region to variety of stress stimuli and stressed heart morphology
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 2, 2022 Category: Cardiology Tags: CORRESPONDENCE Source Type: research
Reply
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 2, 2022 Category: Cardiology Tags: CORRESPONDENCE Source Type: research
