Periventricular rather than deep white matter hyperintensities mediate effects of hypertension on cognitive performance in the population-based 1000BRAINS study
Conclusion:
Our results indicate that PVH may predispose to cognitive impairment associated with hypertension, especially in the domains of nonverbal memory and executive function. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
One year of isometric exercise training for blood pressure management in men: a prospective randomized controlled study
Objective:
Isometric exercise training (IET) over 4–12 weeks is an effective antihypertensive intervention. However, blood pressure (BP) reductions are reversible if exercise is not maintained. No work to date has investigated the long-term effects of IET on resting BP.
Methods:
We randomized 24 unmedicated patients with high-normal BP to a 1-year wall squat IET intervention or nonintervention control group. Resting BP and various clinically important haemodynamic variables, including heart rate (HR), stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR) were measured pre and post the...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Contribution of cyclooxygenase-2 overexpression to enhancement in tonically active glutamatergic inputs to the rostral ventrolateral medulla in hypertension
Conclusion:
Our findings suggest that upregulated COX2 expression enhances the tonically active glutamatergic inputs to the RVLM, which is associated with cardiovascular regulation in hypertension. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Skin capillary alterations in patients with acute SarsCoV2 infection
Background:
Acute SarsCov2 infection is associated with endothelial dysfunction and ‘endothelitis’, which might explain systemic microvascular impairment. The presence of endothelial damage may promote vasoconstriction with organ ischemia, inflammation, tissue oedema and a procoagulant state resulting in an increase in the incidence of cardiovascular and cerebrovascular events. Microvascular thrombosis has been demonstrated in postmortem autopsy of COVID-19 patients; however, few data are available about skin capillary alterations in these patients.
Materials and methods:
We evaluated skin microvascular alte...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Sex differences in pressure and flow waveform physiology across the life course
Cardiovascular disease (CVD) has long been deemed a disease of old men. However, in 2019 CVD accounted for 35% of all deaths in women and, therefore, remains the leading cause of death in both men and women. There is increasing evidence to show that risk factors, pathophysiology and health outcomes related to CVD differ in women compared with men, yet CVD in women remains understudied, underdiagnosed and undertreated. Differences exist between the sexes in relation to the structure of the heart and vasculature, which translate into differences in blood pressure and flow waveform physiology. These physiological differences ...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: REVIEWS Source Type: research
The impact of sodium–glucose cotransporter inhibitors on blood pressure: a meta-analysis and metaregression of 111 randomized-controlled trials
Conclusion:
Sodium–glucose cotransporter 2 inhibitors and combined sodium–glucose cotransporter 1/2 inhibitors produced small reductions in BP in patients with diabetes. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: REVIEWS Source Type: research
Hypertension and atrial fibrillation
Hypertension is the most prevalent cardiovascular risk factor underlying atrial fibrillation and is present in up to 40% of patients with atrial fibrillation. Furthermore, attributable risk studies have shown that a history of hypertension contributes to up to 24% of incident atrial fibrillation. New data suggest that even early forms of hypertension (prehypertension and aortic stiffness) are associated with an increased risk of atrial fibrillation development. Hypertension and prehypertension are therefore critical mediators for the development of atrial fibrillation. Mechanisms for the association between hypertension an...
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: REVIEWS Source Type: research
The effects of hypertension on the prognosis of coronavirus disease 2019: a systematic review and meta-analysis on the interactions with age and antihypertensive treatment
Conclusion:
Hypertension is significantly associated with an increased risk of in-hospital mortality and adverse outcomes in COVID-19. The effect of hypertension on in-hospital mortality among consecutive age groups followed a U-shaped curve. ACEI/ARB treatments do not increase in-hospital mortality and other poor outcomes of COVID-19 patients with hypertension. (Source: Journal of Hypertension)
Source: Journal of Hypertension - November 6, 2022 Category: Cardiology Tags: REVIEWS Source Type: research
Renal denervation in the antihypertensive arsenal – knowns and known unknowns: Erratum
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ERRATA Source Type: research
Neuroadrenergic activation in obstructive sleep apnoea syndrome: a new selected meta-analysis – revisited: Erratum
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ERRATA Source Type: research
Impact of time-restricted feeding and circadian rhythm fasting on blood pressure
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: CORRESPONDENCE Source Type: research
Cuffless blood pressure devices: the gap between patient acceptability and need for validation
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: CORRESPONDENCE Source Type: research
Do conclusions drawn from spot urine sodium measurements agree with the conclusions drawn from the 24-h urine measurements?
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: CORRESPONDENCE Source Type: research
Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women
Objectives:
Veterans, especially women, are three times more to experience sexual harassment and assault [military sexual trauma (MST)] than civilians. As trauma is associated with elevated cardiovascular risk, we investigated whether MST independently contributes to risk for incident hypertension and whether the effects are distinct among women.
Methods:
We assessed 788 161 post-9/11 Veterans (Mage = 32.14 years, 13% women) who were free of hypertension at baseline, using nationwide Veterans Health Administration data collected 2001–2017. Time-varying, multivariate Cox proportional hazard models wer...
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
Mechanisms for blood pressure reduction following isometric exercise training: a systematic review and meta-analysis
Objective:
Isometric exercise training (IET) is established as an effective antihypertensive intervention. Despite this, the physiological mechanisms driving blood pressure (BP) reductions following IET are not well understood. Therefore, we aimed to perform the first meta-analysis of the mechanistic changes measured following IET.
Methods:
PubMed, Cochrane library and SPORTDiscus were systematically searched for randomized controlled trials published between January 2000 and December 2021 reporting the effects of IET on resting BP and at least one secondary mechanistic parameter following a short-term intervent...
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research
