The association of uric acid with mortality modifies at old age: data from the uric acid right for heart health (URRAH) study

Conclusions: These results confirmed the predictive role of SUA for all-cause and CV mortality in older adults, while revealing considerable age-related differences. Mortality risk increased at higher SUA levels in participants aged 65–74, with a prognostic threshold of 4.8 mg/dl. The relationship between SUA and mortality was J-shaped in oldest participants. Large interventional studies are needed to clarify the benefits and possible risks of urate-lowering treatments in older adults.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research