Sex-specific associations of brachial–ankle pulse wave velocity with adverse cardiac remodeling and long-term cardiovascular outcome

This study aimed to investigate the sex-specific association of brachial–ankle pulse wave velocity (baPWV) with adverse cardiac remodeling and cardiovascular outcome. Method: We studied 11 767 patients (57.6% men) with cardiovascular risk factors, whose baPWV was measured. The primary endpoint was composite cardiovascular events. Restricted cubic spline (RCS) analyses were performed to delineate the association of baPWV with echocardiography parameters and risks of cardiovascular events. Results: RCS curves showed that structural/functional echocardiography parameters gradually worsened with increasing baPWV more prominently in women than in men. The prevalence of left ventricular hypertrophy and diastolic dysfunction increases with baPWV increase more steeply in women (P-for-interaction by sex
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research