LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice
ConclusionsLAT1 affects intestinal tumor development in a cell-extrinsic manner through reduced Wnt3 expression in Paneth cells. Our findings may partly explain how nutrient availability can affect the risk of tumor development in the intestines. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 5, 2023 Category: Gastroenterology Source Type: research

Short-term hepatocyte function and portal hypertension outcomes of sofosbuvir/velpatasvir for decompensated hepatitis C-related cirrhosis
ConclusionAchieving SVR24 with SOF/VEL treatment in patients with decompensated hepatitis C-related cirrhosis can be expected to improve hepatocyte function and portal hypertension on short-term follow-up. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 2, 2023 Category: Gastroenterology Source Type: research

Factors for the recurrence of hepatocellular carcinoma after hepatic resection
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 1, 2023 Category: Gastroenterology Source Type: research