Smoking history and severe atrophic gastritis assessed by pepsinogen are risk factors for the prevalence of synchronous gastric cancers in patients with gastric endoscopic submucosal dissection: a multicenter prospective cohort study
ConclusionSmoking history was a risk factor for the prevalence of SGCs in patients with ESD for EGCs, and severe atrophic gastritis assessed by pepsinogen was also a risk factor whenH. pylori was not eradicated. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 14, 2023 Category: Gastroenterology Source Type: research

Treatment with vonoprazan for 3  weeks is not inferior to 8 weeks for the management of gastric ESD: a multicenter noninferiority randomized study
ConclusionThis multicenter randomized study demonstrated that 3  weeks of treatment with VPZ is sufficient for ulcer healing.Trial registry number. UMIN000031564. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 13, 2023 Category: Gastroenterology Source Type: research

Treatment escalation and de-escalation decisions in Crohn ’s disease: Delphi consensus recommendations from Japan, 2021
ConclusionsThese statements provide guidance on how and when to intensify or de-intensify treatment for a broad spectrum of patients with CD. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 11, 2023 Category: Gastroenterology Source Type: research

Correction to: Expert consensus on vaccination in patients with inflammatory bowel disease in Japan
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 10, 2023 Category: Gastroenterology Source Type: research

Correction: Impact of eradication of hepatitis C virus on liver-related and -unrelated diseases: morbidity and mortality of chronic hepatitis C after SVR
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 9, 2023 Category: Gastroenterology Source Type: research

Further notice of omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 7, 2023 Category: Gastroenterology Source Type: research

Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment
ConclusionThis study illustrated the deliverability of sulfomucin in the disease-relevant grafting model to design sulfomucin-producing epithelial units in severely injured distal colon. The current study is the basis for the better promotion of organoids transplantation therapy for refractory UC. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 6, 2023 Category: Gastroenterology Source Type: research