The association between phosphate level at admission and early mortality in acute pancreatitis
ConclusionHyperphosphatemia at admission was independently associated with increased 30-day mortality in patients with acute pancreatitis. Hypophosphatemia at admission was not significantly associated with 30-day mortality. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 18, 2023 Category: Gastroenterology Source Type: research
Medium-chain and long-chain fatty acids are associated with diarrheal predominant irritable bowel syndrome revealed by DESI-MSI
ConclusionsMedium-chain and long-chain fatty acids localized in the colonic mucosa are likely to be potential indicators for the differentiation of IBS-D from healthy subjects which may have implications in the mechanisms and possible preventive measures against IBS.Clinical trial registry registration numberChiCTR2200060224. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 14, 2023 Category: Gastroenterology Source Type: research
Brain activity in response to food images in patients with irritable bowel syndrome and functional dyspepsia
ConclusionsPatients with DGBI, particularly those with FD, disliked fatty foods. The brain activity in patients with DGBI differed from that in healthy controls. Increased activity in the PFC of patients with FD was confirmed. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 12, 2023 Category: Gastroenterology Source Type: research
Trajectory analyses to identify persistently low responders to COVID-19 vaccination in patients with inflammatory bowel disease: a prospective multicentre controlled study, J-COMBAT
ConclusionsMost IBD patients showed a sufficient immune response to COVID-19 vaccination regardless of clinical factors. Assessment of changes over time is essential to optimize COVID-19 vaccination, especially in persistently low responders.Graphical abstract (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 10, 2023 Category: Gastroenterology Source Type: research
Comparison of a novel mini-oral sulfate tablet and the conventional oral sulfate tablet in bowel preparation for colonoscopy: a prospective, randomized, investigator-blinded, multicenter, non-inferior, phase 3 trial
ConclusionsCompared with conventional OST, the novel mini-OST preparation showed similar efficacy, tolerability, and safety, including mild eight solicited AEs and moderate-to-severe AEs.Clinical trial registration NCT05670470. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 5, 2023 Category: Gastroenterology Source Type: research
Efficacy and safety of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma patients with esophageal –gastric varices
ConclusionsAtez/Bev might be an effective therapeutic option in patients with EGV, when appropriate endoscopic treatment for EGV is performed. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - August 1, 2023 Category: Gastroenterology Source Type: research
The impact of the COVID-19 pandemic on the diagnosis, stage, and treatment of esophagogastric cancer
ConclusionsCompared to previous years, the number of esophagogastric cancer diagnoses decreased in the first 2 months of the COVID-19 pandemic, while an increased percentage of patients was diagnosed with incurable disease. Both in the curative and palliative setting, patients were less likely to be treated with a surgical resection. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - July 31, 2023 Category: Gastroenterology Source Type: research
Exploring the challenge of early gastric cancer diagnostic AI system face in multiple centers and its potential solutions
ConclusionsGreat increase of false positives is a prominent challenge for applying EGC diagnostic AI in multiple centers due to high heterogeneity of negative cases. Optimizing AI by adding samples and using novel algorithms is promising to overcome this challenge. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - July 29, 2023 Category: Gastroenterology Source Type: research
